Da miyagun ƙwayoyi "Mikosist": reviews, analogues, farashin. Drug "Mikosist": umarnin don amfani da

Drug "Mikosist" umurci manual ma'anar matsayin antifungal wakili. The aiki sashi daga cikin miyagun ƙwayoyi fluconazole ayyukan - a zabe mai hanawa na sterol kira a cikin fungal Kwayoyin. Yana cike da mutum cytochrome tsarin P450 ba nuna Androgenic aiki, shi ne tasiri game da pathogens na mycosis.

Pharmacokinetics

Bayan baka ko igiyar jini medicament "Mikosist" (mai amfani da ya nuna wannan) da cikin jiki ruwaye da kyallen takarda. A sputum, peritoneal ruwa da kuma articular, yau, nono madara miyagun ƙwayoyi taro kama da cewa cimma a cikin jini jini. Da abun ciki na fluconazole a cikin cerebrospinal ruwa a marasa lafiya tare da fungal meningitis ne tamanin cikin dari na taro a jini wanda, bi da bi, shi ne kai tsaye na gwargwado ga kashi. Lokacin da zarar-kullum aikace-aikace na huɗu-biyar ranar 90 cikin dari da aka samu ma'auni taro. Idan rana ta farko dauki kashi fiye da kima daga cikin saba biyu sau, za ka iya samun rana ta biyu don isa 90 bisa dari na ma'auni jari. Goma sha zuwa goma sha biyu bisa dari na fluconazole daura to jini sunadaran. A gefe jini metabolites ba gano. Pharmacokinetics dogara da gaske a kan kodan, saboda miyagun ƙwayoyi ne excreted yafi nuna su, da kuma game da tamanin cikin dari - canzawa. A cikin sa'o'i uku na dialysis da taro na aiki abu a cikin jini an rage da rabi.

alamomi ga

An shawarar yin amfani da miyagun ƙwayoyi "Mikosist" thrush, ciki har da kowa yana da, watsa, al'aura, a lokacin da sauran siffofin masu cin zali Candida kamuwa da cuta, candidemia, da kuma a gaban dalilai da suka dace da fitowan da thrush. Har ila yau nuna shi ne yin amfani da miyagun ƙwayoyi domin mutane da mucosal candidiasis: pharynx. baka candidiasis ciki har da atrophic, tasowa daga sanye hakoran roba. esophagus. Medicine "Mikosist" umurci manual ya bayar da shawarar gudanar da su marasa lafiya fama da cryptococcal meningitis, ko sepsis, cryptococcosis, cryptococcal kamuwa da cuta daga cikin fata, ko huhu. Ya kuma amfani ga rigakafin komawa da wadannan munanan a marasa lafiya tare da AIDS da kuma a wasu lokuta na immunodeficiency. Magani amfani da su hana fungal cututtuka a mutane da m marurai, mai saukin kamuwa a sakamakon radiation ko jiyyar cutar sankara kayar data. Har ila yau, da miyagun ƙwayoyi "Mikosist" da aka yi amfani da magani na fungal cututtuka makwancin gwaiwa da kuma jiki, zurfin endemic mycoses, ciki har da paracoccidioidomycosis, coccidioidomycosis, histoplasmosis a marasa lafiya tare da al'ada rigakafi da tsarin.

A sashi form, marufi, abun da ke ciki

Biyu sashi siffofin na medicament yana da "Mikosist": capsules da kuma bayani ga jiko. Capsules an sanya dauke da 50, 100 da kuma 150 milligrams na fluconazole. Dukansu suna da wuya gelatin, tare da wani opaque fari jiki, da kuma bambanta kawai a launi lids: y capsules dauke da 50 milligrams na aiki sashi, haske blue hula 100 milligrams - turkos, 150 milligrams - blue. Content ne a powdered m taro ko fari (kusan farin) foda. M sinadaran aiki magnesium stearate, lactose anhydrous, colloidal silicon dioxide, talc, titanium dioxide, masara sitaci, gelatin, Indigo Carmine. Capsules dauke da 50 da kuma 100 MG na fluconazole, da aka ke ~ a kunshe-kunshe da daya, biyu, hudu blisters, bakwai guda kowane. Kuma wadanda ke dauke da 150 milligrams na aiki sashi - a daya ko biyu guda.

Jiko bayani yana da nau'i na m, colorless ko ɗauka da sauƙi a canza launin ruwa. Daya dauke biyu milligrams da milliliter na aiki abu. A sakandare aka gyara su ne ruwa ga allura da kuma sodium chloride. Wadãtu bayani a gilashin vials da ɗari milliliters sanya shi a cikin kwali kwalaye. Daya fakitin ƙunshi daya vial.

Yadda za a yi "Mikosist"? sashi

A saba kashi na fluconazole a cryptococcal kamuwa da cuta shi ne rana ta farko da magani, 400 MG, a cikin wadannan kwanaki - 200-400 milligrams. A tsawon lokaci da far dogara a kan tabbatar mycological nazarin da na asibiti inganci, shi ne sau da yawa ba fiye da shida - makonni takwas. A cryptococcal meningitis amfani da wani magani "Mikosist" umarnin don amfani da shawarar da goma - goma sha biyu makonni bayan sakamakon da aka korau nazari samfurori da cerebrospinal ruwa. Fama da cutar kanjamau bayan kammala na farko da magani aka nuna don rigakafin komawa da cryptococcal meningitis na dogon lokaci na liyafar nufin "Mikosist" a wani kashi na ba kasa da ɗari biyu milligrams kowace rana.

A marasa lafiya da watsa candidiasis, candidemia da sauran masu cin zali Candida cututtuka, yawanci a rana ta farko na shan hudu milligrams na miyagun ƙwayoyi, da kuma a cikin 'yan kwanaki - ɗari biyu milligrams kullum. A hali mai tsanani na tsari yisti kashi iya karu zuwa ɗari takwas milligrams kowace rana. Magani ya kamata a ci gaba ga akalla makonni biyu bayan da kawar da cututtuka da kuma samun wani mummunan jini al'ada. Idan oropharyngeal candidiasis, ciki har da a marasa lafiya tare da mai illa rigakafi, miyagun ƙwayoyi sashi da rana ne da hamsin - ɗari da milligrams, shan shi ya zama wani lokaci na bakwai - kwana goma sha huɗu. A atrophic candidosis sakamakon saka hakoran roba yawanci wajabta kullum ci hamsin milligrams da miyagun ƙwayoyi a hade tare da antiseptic. Jiyya ci gaba da makonni biyu. Ga wasu Candida cututtuka (candiduria, esophagitis, fata da kuma mucosal candidiasis) kullum kashi na magani ne da hamsin - ɗari da milligrams, far ne goma sha huɗu - har kwana talatin.

Domin kawar da bakin farji candidiasis medicament "Mikosist" umurci manual nuni dauko singly a wani adadin na 150 milligrams. Yana iya zama na hudu - watanni goma sha biyu da zarar wata daya zuwa sha daya kwantena (150 MG) don rage mita na dakwai, komowan cutar. Sau da yawa wajabta candidiasis a Bugu da kari ga miyagun ƙwayoyi "Mikosist" kyandirori, misali, "Terzhinan", "Clione-D", "Ginezol". Dangane da mataki na hadarin fungal kamuwa da cuta, don rigakafin candidiasis da kullum shawarar kashi na miyagun ƙwayoyi iya bambanta daga hamsin zuwa ɗari huɗu da milligrams.

A cikin hali na zurfin endemic mycoses iya bukatar dauki da miyagun ƙwayoyi a sashi na biyu da ɗari - ɗari huɗu da milligrams da rana na tsawon shekaru biyu. A tsawon lokaci da magani dogara a kan mutum da kuma na asibiti hoto: tare da coccidioidomycosis, shi zai iya Range daga goma sha zuwa ashirin da hudu watanni, paracoccidioidomycosis - daga biyu zuwa goma sha bakwai watanni, histoplasmosis - daga uku zuwa goma sha bakwai watanni.

aikace-aikace dokoki

Igiyar jini drip shiri ya kamata a gudanar a wata kudi na ba fiye da ashirin milliliters da minti. Babu bukatar canza kullum kashi a lokacin da canja wurin marasa lafiya daga igiyar jini to baka magani. A bayani ga jiko da jituwa tare da dvadtsatiprotsentnym glucose bayani. mafita Hartman da Ringer. bayani na sodium hydrogen carbonate, potassium chloride , a wani glucose, sodium chloride (0.9%). Jiko iya za'ayi amfani talakawa fluconazole kaya for transfussion, ta amfani da daya daga cikin wadannan mafita.

illa

Mafi yawa daga cikin marasa lafiya da suke dauki da miyagun ƙwayoyi "Mikosist 'reviews game da shi ya bar mai kyau. Drug zahiri yadda ya kamata gusar fungal cututtuka amma zai iya sa illa effects. Saboda haka, daga narkewa kamar tsarin ne da hadarin tashin zuciya, flatulence, mahaukaci hanta aiki, da matsaloli tare da ji na iyawa, zawo. Har ila yau, wasu mutane koma zuwa abin da ya faru na ciwon kai, seizures, juwa. Suka ce cewa irin wannan mamaki sun taso jim kadan bayan shan miyagun ƙwayoyi, "Mikosist". Sharhi kan sauran marasa lafiya dauke da bayani game da ci gaban da far miyagun ƙwayoyi alerji a cikin nau'i na erythema, rash, angioedema, urticaria. Daga cikin sauran yiwu illa kamata a lura da alopecia, na ramin zuciya fibrillation, illa koda aiki, hypertriglyceridemia, hypercholesterolemia, kuma hypokalemia.

contraindications

A cikin irin capsules kamata ba za a wajabta magani don yara a karkashin watanni shida na shekaru (ga jarirai a yarda a yi amfani da miyagun ƙwayoyi a cikin nau'i na bayani ga jiko). Kada ka yi amfani da wannan magani "Mikosist" lactating mata (mata masu ciki da bukatar sanya shi tare da kula), kazalika da mutane tare da high ji na ƙwarai to sinadaran kunshe a cikin abun da ke ciki. Tare da karuwar bukatar amfani da hankali ga marasa lafiya da na koda / hanta insufficiency, rashin ha} uri na acetylsalicylic acid.

yawan abin sama

"Mikosist" rubuce lokuta na miyagun ƙwayoyi yawan abin sama. Reviews mutanen da suka dauki da miyagun ƙwayoyi a wuce kima allurai, nuna ci gaban da zawo, tashin zuciya da amai. A tsanani lokuta, akwai bayyanar seizures, paranoid hali, hallucinations. A mutum tare da bayyanar cututtuka na yawan abin sama da ya kamata a dauka zuwa asibiti, inda ciki lavage za a yi masa, dialysis, tilasta diuresis, symptomatic far.

"Mikosist" ko "Fluconazole": wanda shi ne mafi alhẽri?

To, tambayar akai-akai tambaye ta marasa lafiya. A gaskiya, duka biyu kwayoyi ne guda, zamu iya cewa su ne m. Iyakar abin da bambanci shi ne cewa da miyagun ƙwayoyi "Mikosist" da ke sa da Hungarian Pharmaceutical kamfanin "Gedeon Richter", yayin da "Fluconazole" - da shiri na cikin gida samar. Hakika, wannan yana da tasiri kai tsaye a kan kudin da magunguna. Zabar abin saya - "Mikosist" ko "Fluconazole" - da yawa fi son zuwa da miyagun ƙwayoyi, wanda shi ne mai rahusa. Lalle ne, wani gagarumin bambanci a price. Saboda haka, don marufi da "Mikosista" (daya kwantena dauke da 150 milligrams na fluconazole) dole ka biya wani talakawan na 295 rubles, yayin da guda kunshin "Fluconazole" kudin kawai 8-20 rubles. A talakawan farashin mai 100 ml kwalban bayani ga jiko "Mikosist" ne 311 rubles.

Game da pharmacological Properties na biyu da kwayoyi, su ne kusan m, bambanci za a iya gani sai dai cewa kudi na sha: kamar yadda samuwa data, matsakaicin maida hankali a cikin jiki "Fluconazole" da aka kai bayan 1-2 hours bayan aikace-aikace, da kuma "Mikosista" - 0.5 -1.5 hours. Duk da haka, ba dukan marasa lafiya da amsa zuwa ga biyu magunguna daidai. Wasu ba su ga wani bambanci tsakanin su, yayin da karshen yi imani da cewa ingancin dogara a kan farashin, wanda ke nufin cewa wani magani ne mafi tsada, da mafi alheri. Za ka iya sau da yawa sami reviews a wadda mata suna da'awar cewa bayan shan "Fluconazole" thrush zo da baya, amma "Mikosist" yarda ka rabu da shi har abada. A cikin wani hali, da zabi ne naki.

analogs

Bugu da kari to "Fluconazole", akwai wasu magunguna da za su iya maye gurbin da miyagun ƙwayoyi "Mikosist". Analogs medicament da ciwon kamar yadda aiki sashi guda abu, suna da kyau wakilci. A cikin irin capsules domin lura da yisti da sauran fungal cututtuka, za ka iya amfani da "Diflucan" kwayoyi "Flucostat", "mikomaks" da sauransu. An tasiri wajen ne "Mikoflyukan" (Allunan). "Mikosist" daga duk wadannan daban-daban analogs da Manuniya kamar bioavailability, rabin-rai, da kudi na sha.

miyagun ƙwayoyi interactions

Wajibi ne a hankali saka idanu da prothrombin lokaci a marasa lafiya samun fluconazole tare da kai tsaye ba anticoagulants coumarin kungiyar, saboda akwai wani hadarin kara VWP. Lokacin da concomitantly da sulfonylureas miyagun ƙwayoyi "Mikosist" iya tsawanta da rabin-rai daga gare su, saboda haka kana bukatar la'akari da yiwuwar qarancin ruwa. A cikin hali na fluconazole da phenytoin sharing yiwu asibiti gagarumin mataki na karuwa daga karshe taro, sabili da haka, idan ya cancanta a hade samun da kashi ya kamata a rage. Tare da m nufin "Mikosist" da kuma rifampicin za a alama karu a maida hankali fluconazole haka kashi "Mikosista" da ake bukata domin kara. A hada da yin amfani da wani azole wanda aka samu da wani medicament a hade tare da terenadinom contraindicated, kamar yadda zai iya ci gaba mai tsanani, rai-barazanar arrhythmia. Idan ka dauki magani "Mikosist" tare da cisapride, za a iya bayyana a ke so halayen a kan wani ɓangare na zuciya, ciki har da na ramin zuciya tachycardia. Tare da na lokaci daya amfani da fluconazole da theophylline rage talakawan yarda kudi daga jini na karshe jini, sabili da haka qara da alama na cin gaban ta mai guba illa da kuma yawan abin sama.

tsõratar

Ya kamata ci gaba da lura da "Mikosist" har da na asibiti da kuma hematological gafarta musu. Sakacin an daina far ne fraught tare da komowan cutar. Kamar yadda aka ambata a riga, marasa lafiya da na koda insufficiency kamata amfani da miyagun ƙwayoyi da matsakaicin taka tsantsan, saboda shi ne excreted yafi da koda. Sashi a lokacin dogon lokacin da magani ya kamata a yi, shan la'akari da CC. Lokaci-lokaci fluconazole shafi mai guba effects a kan hanta, don haka wajibi ne a saka idanu aiki na wannan jikin. Bayan ganewa na raunuka bayyanar cututtuka ya kamata a daina shan magani.

Marasa lafiya a kan bango na "Mikosist" yana nufin kasance rare sightings exfoliative cutaneous halayen, kamar mai guba epidermal necrolysis da Stevens-Johnson ciwo. Marasa lafiya da m neoplasms da kuma AIDS ne mafi yiwuwa zuwa fitowan da m fata halayen lokacin da yin amfani da shirye-shirye dauke da fluconazole. Idan a lokacin da magani daga waje fungal kamuwa da cuta da rash bayyana, da miyagun ƙwayoyi kana so ka soke. Idan ka fuskanci rash in mutane tare da cin zali ko tsari fungal kamuwa da cuta likita kamata karfafa kulawa da kuma warware da miyagun ƙwayoyi, a cikin taron da cewa za su ci gaba erythema multiforme, ko bullous raunuka. A lokacin jiyya, magani "Mikosist" (reviews tabbatar da shi) na iya haifar da dizziness, don haka marasa lafiya bukatar ya zama musamman hankali lokacin da yin aiki tare da dabara da kuma gudanar da motocin.