Antibodies zuwa thyroid peroxidase

Thyroid peroxidase enzyme ne glycoprotein yanayi. Wannan microsomal antigen ne mafi muhimmanci a cikin kira na thyroid ji ba gani.

A autoimmune aiwatar shafe autoantibodies da kyallen takarda kafa da thyroid gland shine yake. Cuta na thyroid aiki ne sau da yawa hade da shi. Na bayar da muhimmanci a cikin wannan yanayin ne antibodies da thyroid peroxidase.

Cincirindo gano a Hashimoto ta thyroiditis. A karshe matakai na atrophic matakai a cikin thyroid su matakin aka saukar a wasu lokuta zuwa undetectable matakan.

Antibodies zuwa thyroid peroxidase sukan gano tare da kaburbura 'cuta. A lokacin da suka ganewa na cuta alaka hadarin dalilai ga m samuwar hypothyroidism.

Lokacin da laulayi tireoditu Hashimoto mata da antibodies zuwa tireperoksidaze za a iya gano a lokacin daukar ciki. Tare da su ya karu maida hankali a cikin ta farko trimester a can ne alama bunkasa cutar bayan haihuwa.

Antibodies zuwa thyroid peroxidase kuma iya nuna gaban sauran thyroid pathologies. Wadannan sun hada da, musamman, ya kamata sun hada adenoma, goiter, thyroid ciwon daji. Bugu da ƙari kuma, antibodies ne detectable a lafiya mutane (kamar 10% na mata da kuma 5% maza).

Laboratory da bincike kan su ganewa kamata a da za'ayi la'akari da siffar da autoimmune tsari. Shi ne ba togiya da ciwon sukari (insulin-dogara), pernicious anemia, adrenal insufficiency (autoimmune), na tsari lupus erythematosus.

Aikace-aikace na mutum kwayoyi iya tsokana ci gaban hypothyroidism, wanda ake dangantawa da bayyanar autoantibodies. Wadannan sun hada da, musamman, lithium kwayoyi, "Amiodarone". Irin wannan sakamako ne halayyar immunostimulatory far (misali, interferon).

Tabbatar da dalilin da antibodies ne isasshe m gwajin for ganewa na autoimmune halakar da thyroid gland shine yake. Kamar wancan ne mafi bincike darajar ya daidai score.

Ka lura da cewa tsayar da wanzuwar wani autoimmune cuta daga cikin thyroid gland shine yake kawai a kan tushen da gano high index antibodies ba zai yiwu ba.

Cikakkar alamomi ga binciken ne kaburbura 'cuta, hadarin da hasashen da na hypothyroidism a kan ruwan dare bango na kara maida hankali thyroid-haramta motsa hormone. Bugu da kari, da bukatar bincike na faruwa a autoimmune thyroiditis a primary hypothyroidism, kazalika da hasashen da na ci gaban zubar thyroiditis a marasa lafiya a hadarin.

Domin zumunta alamomi sun hada da

- bambanci ganewar asali subacute da autoimmune (lymphocytic) thyroiditis a kan bango na transistor thyrotoxicosis,

- ganewar asali autoimmune siffofin a kan bango na euthyroid yaxuwa ko nodular goiter,

- tsinkaya hypothyroidism a marasa lafiya a hadarin, farkon daukar ciki.

A lura da gano cututtuka bi-up nazari ne da bai dace ba. Wannan shi ne saboda cewa ta matakin yana da wani prognostic darajar a lokacin da suka kamu da cutar.

A gaban da alama na autoimmune thyroid cuta shawarar retested a farko da na biyu a shekara ta kallo a cikin harka a primary nazari, babu antibodies zuwa thyroid peroxidase. A kullum ga m mutum ne har zuwa 35 iu / ml.

A yau babu tabbatar ta hanyar kimiya da kuma sauti hanyoyin kwantar da hankali a AIT (autoimmune thyroiditis). Tare da wannan, a kan bango na kafa hypothyroidism, thyroid peroxidase antibodies lokacin da tashe, da lura da cuta ne ba matsala ga likitoci. Nada ta hormone maye far miyagun ƙwayoyi "Levothyroxine."