Prothrombin index, kudi da kuma darajar

Prothrombin index, da kudi na wanda yake daidai da 95-105%, - shi ne daya daga cikin Manuniya characterizing jini clotting. Jini clotting - wani hadadden tsari wanda ake da za'ayi tare da sa hannu na wani cascade na musamman sunadarai kira coagulation dalilai. A kunnawa da wannan tsari ne yiwu a hanyoyi biyu - na ciki da kuma na waje.

Yana prothrombin index characterizes kunnawa da coagulation via da extrinsic hanya. Shi ne kamar haka: a take hakkin da mutunci kyallen takarda (rauni) da aka kasaftawa ake kira nama thromboplastin, musamman gina jiki samu a duk jikin kyallen takarda. Yana triggers wani cascade dauki wanda shigar da sauran clotting dalilai (V, VII, kuma X, II, I), jẽre kunna juna. Daga qarshe, mai jini gudan jini aka kafa da kuma zub da jini tsaya a nan ba.

Menene prothrombin index

Clotting dalilai an kafa a hanta. Daga cikin wadannan, II, V, X ne bitamin K-dogara. Tare da rashin bitamin su kira zai lalace. Haka kuma, akwai keta hemostasis. Sanin prothrombin index, wanda aka sani da kudi, your likita yiwu:

1. Aiki Rate yiwu II, V, VII kuma X ma clotting dalilai
2. The girma na wannan nuna alama ya yi hukunci da aiki na hanta
3. A jikewa na bitamin K
4. A janar jihar na jini coagulation tsarin
5. A cewar wannan nuna alama, za ka iya saka idanu da tasiri na anticoagulant far.

Kamar yadda ƙaddara da prothrombin index

Prothrombin index aka ƙaddara a capillary ko venous jini. A karo na biyu idan azumi jini da aka dauka a cikin wani gwajin bututu da wani anticoagulant a cikin wani rabo na 9: 1. Kamar yadda amfani anticoagulant sodium citrate. A cikin dakin gwaje-gwaje, da jini ne centrifuged. A sakamakon jini da ake amfani da tabbatar da dalilin da prothrombin lokaci (PT). Kullum MF ne a cikin kewayon daga 12 zuwa 20 seconds, dangane da ayyukan da thromboplastin amfani a cikin shakka daga cikin dauki a cikin dakin gwaje-gwaje.

Sanin haƙuri ta PT, za ka iya lissafta da PI, watau, prothrombin index, wanda shi ne na kullum a daban-daban dakunan gwaje-gwaje kuma iya zama a bit daban-daban. Shi ne daidai da rabo px lafiya da mutum zuwa wani PV haƙuri, ta tara da 100:

PI = PV lafiya. / SA rashin lafiya. X 100 (al'ada 95-105%)

The asibiti muhimmancin PI

A mafi girma PT coagulation ko prothrombin wanda kullum na 12 zuwa 20 seconds ne taqaitaccen, kuma PI ƙaruwa. Wannan na iya zama a lokacin daukar ciki, tare da m rauni a lokacin da jini ya zo a da yawa daga nama thromboplastin.

Conversely, MF ƙaruwa da kuma rage-rage tare da rage a PI clotting, kamar a cikin hali na nakasar rashi na clotting dalilai, tare da tsananin cutar hanta, da wani rashi na bitamin K (wanda na iya faruwa a cholestasis, dysbacteriosis, disrupting Gut aiki). PI rage-rage tare da low fibrinogen ko wani aikin tawaya, tare da ciwo DIC, a gaban abubuwa da hana clotting.

Mene ne INR

Jiyya na kai tsaye ba anticoagulants halitta rage prothrombin index. Its kullum iya zama da kansa a cikin kowane dakin gwaje-gwaje. Saboda haka, domin a iya kwatanta gwajin sakamakon samu a dakunan gwaje-gwaje daban-daban, da aka gabatar a daidaita gwajin kamar INR. Wannan lissafi index. Aka ƙaddara dangane da rabo daga cikin prothrombin lokaci na haƙuri, al'ada darajar MF da kuma digiri thromboplastin ƙwarai fihirisar (ISI).

INR = (PT b th / MF rate) a cikin mataki na ISI

A wani m mutum da INR a cikin kewayon 0, 8-1,2.

Wannan nuna alama da ake amfani a sa idanu da tasiri na anticoagulants mataki. A lura da anticoagulant lokacin coagulation an rage (misali bayan tiyata a zuciyarsa) INR ya kamata a karu zuwa 2-3. Tare da kara INR clotting an rage. A rabo tsakanin PI da INR ne irin wannan cewa, a karu a PI index ya karu INR.