Tubulointerstitial nephritis, m kuma na kullum siffofin: Bayyanar cututtuka, Sanadin kuma Jiyya

Tubulointerstitial nephritis ciki na kowa koda cuta da kuma raunuka tashoshi manyan zuwa tabarbarewar sashin jiki aiki. A cutar halin m canje-canje a cikin tsarin interstitial koda nama. Akwai biyu iri da cutar - m kuma na kullum. A wa'azi na da yawa magunguna zuwa cikin jikin mutum, shi an ambaci cewa kwayoyi shafe via kodan. Kuma tunani uncontrolled liyafar magunguna ba Yunƙurin zuwa cuta saboda wani alerji zuwa wasu magunguna ko na ganye far. The rashin lafiya kuma ya auku a matsayin sakamako koma kamuwa da cuta.

Don gane tubulointerstitial nephritis, da yin amfani da zamani da bincike dabaru na jiki, wato, duban dan tayi, fitsari da kuma jini gwaje-gwaje, likita tarihi data tarin, da koda biopsy. Kammalawa game da reversibility da cutar dogara ne a kan mai tsanani daga cikin rauni da kuma lokaci na neman taimakon likita.

A Sanadin cutar

Wani lokacin liyafar na maganin rigakafi ko wasu anti-kumburi kwayoyi aka mĩƙe na dogon lokaci. Kuma koda lalacewa auku bayan karfi da sinadaran guba, nauyi karafa. Musamman yankunan da suke ethanol tururi. Tubulointerstitial nephritis iya faruwa saboda dalilai da yawa:

• bayan jurewa da wani kwayar cutar - a 46% na lokuta.
• mai guba bayyananen tsokane rashin lafiyan cuta a cikin 28,3%.
• rayuwa cuta a cikin jikin inganta faru na da cuta a cikin 13,9%.
• cuta na Sistem ayyuka ureters - 8.8%.
• kwayoyin haddasawa da kuma rigakafi - 0.9% da cutar.
• dalilai da dama a lokaci daya lura a 2.5% na lokuta.

Kullum siffofin da cutar suna lalacewa tsanani take hakki na kirki cytomembranes, koda dysplasia nama rayuwa canje-canje, nakasar anomalies kuma samu ureters.

ganewar asali

Yana gudanar da wani yawan karatu na jiki da kuma dakin gwaje-gwaje hali. Kuma kawai sai da ganewar asali ne m. Tubulointerstitial nephritis ana sa ran a cikin wani haƙuri tare da fitowan na ma'ana bayyanar cututtuka suna kamu raba bayyananen nunawa.

da kullum yanayi da cutar ne sakamakon infiltration da atrophy na tashoshi a cikin jikin mutum na dogon lokaci. Gabar aiki ne hana hankali - shekara da shekaru. A haƙuri ke zuwa wani likita idan akwai m cututtuka, kamar ciwo a cikin kodan, fata rashes, da sauransu. Su tsĩrar da shi da gagarumin rashin jin daɗi. Cuta rinjayar kawai biyu ko koda lalacewa kadai.

A wani dakin gwaje-gwaje binciken, fitsari uric fili bayyane precipitate da wani babban abun ciki na erythrocytes da leukocytes. A lokaci guda akwai cikakken babu erythrocytes dismorfnogo irin kuma kawai karamin bayyanuwar hematuria. A gaban eosinophils a cikin fitsari ba a halin da gaban da cuta, tun kawai 50% na lokuta su ne sakamakon cutar. Idan ba su zama a duk, to, wannan ya nuna cewa cutar ne mãsu fakowa ba. Proteinuria gano m yi, amma idan jikin ya riga ya ɓullo da glomerular Pathology sa da yin amfani da maganin rigakafi, alhãli kuwa wannan adadi ya kai nephrotic matakin.

A cikin bincike na jini m tubulointerstitial nephritis bayyana kanta hypercalcemia. Take hakkin tashar aiki kai ga rayuwa acidosis. Lokacin duban dan tayi ne da yawa ƙãra kudi echogenicity saboda jiki busa da infiltration tsari. Amurka ya nuna karuwa a koda size karuwa index rediyoaktif gallium da leukocytes rajista a lokacin radionuclides. A tabbatacce scan sakamakon nuna tubulointerstitial nephritis. Ganowa, saukar da wani mummunan sakamako, wasu hanyoyin dole a bayar.

symptomatology da cutar

A farkon matakai na cutar da wani bayyanar cututtuka. Wasu marasa lafiya da ba su sani na tasowa Pathology. A baya, saukarwa da cutar hanya da wani sakamako ma'ana fasali:

• rashes bayyana partially ko a kan dukan surface na jiki qazanta da harafin itching.
• Kananan ƙaruwa a zazzabi range, mai tsanani lokuta suna alama da zazzabi.
• koda zafi da aka ji kullum ko m wucewa kai hare-hare.
• ƙara gajiya, da mãsu haƙuri ji barci Rolls.
• matsa lamba surges faruwa wani kwakkwaran dalili ba.
• akwai polyuria.

Mutane da yawa bambancin bayyananen alama tubulointerstitial nephritis. Alamun lura a cikin nau'i na zazzabi da kurji, amma wasu daga cikin wadannan canje-canje a cikin jiki ne bai isa ba, ga ganewar asali. A rash auku wata guda bayan da mataki na toxin ko for 3-6 kwanaki. Wannan ya dogara da jihar da kwayoyin da kuma ta mayar da martani ga allergen. Alama nauyi asara, zafi a ciki da kuma a cikin mayar da sama da gindi.

A cuta, haƙĩƙa, sun shige a cikin kullum mataki, daban-daban a tsawon m bayyanar cututtuka, Qarfafa tare da lokaci. Wasu mutane ci gaba polyuria da nocturia. Hawan jini da kuma kumburi daga cikin wata gabar jiki ne kiyaye matsayin dogon har shi ne na koda gazawar. A bayyanar cututtuka bayyana a cikin jerin, ne halayyar da m mataki na cutar.

brightism

Cutar zama na kullum bayan da m hanya. Amma irin wannan hali ne rare. Mafi sau da yawa, na kullum nephritis ci gaba bayan jurewa kamuwa da cuta, m rayuwa cuta a cikin jiki, na yau da kullum magani maye. Tubuloinsterstitsialnye kullum nephritis a kan duban dan tayi ya nuna glomeruli a al'ada yanayin ko hallaka. Tubules yi ba ya nan gaba ɗaya ko maras kyau. Bayanan kula da daban-daban gibba tashoshin - daga quntata wa wani m kama membranes.

Koda nama ne mai saukin kamuwa zuwa fibrosis da kumburi. Idan yawa fibrosis ne ba ya nan, da parenchyma dubi kusan lafiya. Atrophied koda da kananan size da ãyõyin jeri na bangaren. Alamun na kullum nephritis ne kamar irin waɗanda samuwa a cikin m mataki, amma da kasa m bayyana. Leukocytosis kuma Ya ƙãra erythrocytes ne rare. Kullum hanya da cuta ne mai hadarin gaske, saboda haka kana bukatar a hankali sauraron bayyanar cututtuka a farkon matakai da cutar. Jinkiri a magani kai ga koda gazawar, wanda shi ne fraught tare da wata matsala.

A m Hakika na cutar

Sau da yawa da shi ya auku saboda rashin iya kai-magani ba tare da tuntubar likita. A rashin iyawa da kodan zuwa aiki, bayyanar m kumburi tafiyar matakai bayyana bayan wani dogon lokaci amfani da magani daga beta-laktamidnyh maganin rigakafi.

M nephropathy ne halin gaban gefe edema da kuma kumburi infiltration. Sun mika ga koda nama. wani lokacin yana daukan 'yan makonni kafin bayyanar kwatsam bayyanar cututtuka. Sa'an nan ci gaba m na koda gazawar, wanda aka jawo da untimely qaddamarwa na lura da gudana daukan hotuna zuwa wani irritant.

yara jades

A ikon kauce wa ci gaban da cuta a cikin shimfiɗar jariri, da zama wani dace ziyara a wani likita a hali na wani ailments, jere daga colds. Don kai-ba zai yiwu ba, kawai aikatawa pediatrician zai zabi magunguna da cewa ba ya cutar da yaro ba kafa na rigakafi da tsarin.

Tubulointerstitial nephritis a yara bi da a karkashin kulawa da wani gwani. Bi-biye sanya warkewa rage cin abinci, ba tare da wanda tabbatacce sakamakon da aka samu mafi wuya. A cikin hali na gudãna nephritis koda kamuwa da cuta magani ba zai yiwu, to koma ga sashin jiki dasawa. Ga yara halayyar undulating hanya da cutar tare da wani dogon rashin laka lokaci.

hangen nesa

Lokacin koda aiki ne sosai saboda da amfani da kwayoyi, tubulointerstitial nephritis faruwa. Jiyya a m lokuta da ake bukata. Tsaya shan magani, da kuma buds fara al'ada aiki a 2-2.5 watanni. Wani lokaci saura sabon abu ne a gaban scarring. Lokacin da cuta daga wani etiology kawar da dalili, amma da cutar ne reversible. A tsanani lokuta ne koda gazawar da kuma fibrosis.

Hasashen na kullum siffofin nephritis dogara a kan gudun ganewa da kuma rage Pathology kafin za su samar komowar fibrosis. Idan ba za ka iya gyara kwayoyin, mai guba da kuma na rayuwa canje-canje, cuta ke shiga thermal na koda gazawar.

cuta magani

Lokacin da na farko bayyanar cututtuka da cutar bukatar ganin likita. Kawai ya zai karba daidai da m magani. Far ga kowane haƙuri shi ne wani mutum. Amma, misali, a gaggauta maida daga cikin m lokaci na rashin lafiya, da kuma wani lokacin na kullum glucocorticoid amfani. Yanayin aiki aiwatar damuarn angiotensin hanawa.

A koda biopsy

A hanya da dangantaka da bincike shisshigi a gano koda cuta. Shi ne da kau da nama yanka domin microscopic jarrabawa. Ta hanyar wani bakin ciki sirinji allura faruwa kananan adadin koda abu. Wannan binciken taimaka yadda ya kamata sanin sinadaran abun da ke ciki na nama da kuma zabi na jiyyar.

Alamomi ga biopsy hanya

A binciken da biopsy Hanyar da ake sa a cikin wadannan lokuta:

• Har zuwa karshen kasa gano dalilin kullum ko m cututtuka.
• Shin da ake zargi nephritis.
• Hanzari m na koda gazawar.
• Akwai wani hadadden dauke da kwayar cutar aetiology.
• A dakin gwaje-gwaje karatu na fitsari gano wani admixture na jini da kuma gina jiki.
• Jini gwajin ya nuna babban adadin uric acid, creatinine, urea.
• Mayakan Oncology.
• Transplanted koda aiki matsaloli.
• Akwai bukatar sanin ko har na lalacewa.
• Don saka idanu da ci gaba da magani.

iri biopsy

A hanya ne yake aikata ta hanyar fata. An za'ayi da allura da kodan da aka sarrafawa da wani X-ray ko duban dan tayi. Don sauƙaƙe wuri na jiki da aka saka a cikin jijiya daga wani bambanci a launi tsaka tsaki abu. Open biopsy hanya ne halin da shinge na karamin adadin nama kai tsaye a lokacin tiyata. Alal misali, a lokacin da cire kafa Cancer neoplasms. Ya nuna yadda waɗanda suka yi zub da jini, ko akwai daya kawai koda tana aiki. Wannan ne yake aikata to rage hadarin daukan hotuna da shi.

Hadin gwiwa cystoscopy da biopsy ne da za'ayi a cikin hali na gaban duwatsu a cikin ureter ko na koda kafafuwa. An yi a cikin aiki dakin da kuma samar da wani gabatarwar da wani m tube ga ciki dubawa na ureter. Transjugular view biopsy gabatarwa ne na catheter cikin zaba koda jannayẽnsa. Ana amfani da marasa lafiya da kiba, na kullum numfashi insufficiency da matalauta jini clotting a lokacin da babu wani daga cikin sama da hanyoyin da aka ba da za'ayi saboda barazana ga rayuwa da kuma ba ya gane tubulointerstitial nephritis.

A ƙarshe, dole ne a ce, cewa cutar alama asymptomatic, ba damun haƙuri a zahiri yana bukatar lokaci don gane. Da kuma rikitarwa da untreated nephritis rage koda aiki da kuma haifar da komowar sakamakon.