Abun ciki zai iya haifar da cutar Alzheimer

Rashin ciki a cikin daddare kuma zauna a cikin rana kamar yadda a cikin jirgin ruwa ... Mutane da yawa suna fuskantar irin wannan rashin barci. Bisa ga wani sabon binciken, rashin lafiyar rashin barci da kwanciyar hankali na rana zai iya ƙara haɗari ga cutar Alzheimer.

Binciken sha'awa

A wannan binciken, an kira mutane 101. Babu wani daga cikin wadannan mutane da ke da rashin fahimta. Yawan shekarun su ne shekaru 63.

Bayan masu halartar gwaji sun cika tambayoyin da tambayoyi game da ingancin barci, kowanne daga cikinsu ya gabatar don gwajin su. Manufar bincike shine gano ainihin alamun alamar alama, waxanda suke da alamun yanayin cutar Alzheimer. Masana kimiyya sun tabbatar da cewa rashin barci da barci da rana suna haɗuwa da karuwa a cikin cutar.

Hanyoyin beta-amyloids a kan abin da ke faruwa a kwakwalwa

Duk da yake dangantakar dake tsakanin rashin barci da dementia ba wai 100% ba ne, yawancin nazarin dabba sun gano cewa yayin barci, ikon da kwakwalwa ke ware toxins kamar amyloids na beta (sunadarai masu guba). Su ne wadanda suke haifar da bayyanar alamun kwakwalwa a cikin kwakwalwa a marasa lafiya da cutar Alzheimer, kuma yana yiwuwa daidai wannan tsari ya faru a cikin mutane. Gabatar da amyloid a cikin kwakwalwar nama shine farko da aka sani na cutar Alzheimer kuma yana faruwa a gabanin alamomin lalata.

Duk masu halartar binciken sunyi hadari ga cutar Alzheimer. Abubuwan da ake bukata da kwayoyin halitta, tarihin iyali da kuma bayanai game da kwayoyin APOE da suke hade da yiwuwar ƙaddamar da ayyukan tunanin mutum sun kasance cikin la'akari. Kowane mutum ya ba da kimanin yawan lokutan barci, ingancin barci, kuma ya lura da barcin rana.

"Masu halartar wannan binciken sun kasance suna shirye su shawo kan ƙuƙwalwar lumbar don ci gaba da binciken kan matsalolin Alzheimer," in ji babban marubucin Barbara Bendlin na Cibiyar Nazarin Ciwon Bincike a Wisconsin. "Yin nazarin wannan ruwa ya ba mu damar duba irin wadannan alamun da ke hade da cutar Alzheimer a matsayin alamu, da alamun kumburi da lalacewar kwayoyin jijiya."

Rashin barci ba ya jawo cutar a duk lokuta

Ya kamata a lura cewa ba duk wanda ke fama da matsalar barci yana tasowa cutar Alzheimer ba. Barbara Bendlin, wanda shi ne mataimakin furofesoshi na likita a Makarantar Medicine a Jami'ar Wisconsin, ya shaida wa New York Times: "Muna kallon kungiyoyin jama'a kuma muna lura da dangantakar mafarki marar kyau tare da alamomi na neurodegeneration. Amma idan ka dubi mutane, ba dukkanin alama ne saboda rashin barci. "

Gwaje-gwajen akan ƙuda

Wannan binciken na karshe shi ne ci gaba da binciken kimiyya na baya wanda ya nuna cewa barcin damuwa zai iya zama dalilin lalata. Sauran binciken sun bayyana hanyar haɗi tsakanin rashin barci na yau da kullum da kuma ci gaban amyloid plaques. Binciken da aka yi a cikin mice ya nuna cewa a cikin dabbobin da suka barci, an rage adadin beta-amyloid. Cikakken cikakken yakamata ya kwantar da kwakwalwar ƙuda daga abubuwa masu guba.

Bendlin da abokan aikinta suna kallon mutanen da ke cikin haɗarin Alzheimer. Abubuwan da za a bincika a cikin ɗakin barci, inda za a gudanar da gwaje-gwajen gwagwarmaya.

Shin ci gaban cutar zai inganta yanayin barci?

"Idan ya bayyana cewa saitawa da ke kawar da irin wannan yanayin yanayin rashin barci zai haifar da rashin amyloid a cikin kwakwalwa, to, zai bada goyon baya mai karfi don maganin warkewa kafin mutane su fara nuna rashin lafiya da ya shafi cutar Alzheimer "- in ji Bendlin.

Bendlin kuma ya furta cewa kafin a tambayi wani likitan ne ya rubuta maka kwayar barci, kana bukatar ka san ko magani yana rinjayar amyloid don barci. Mataki na gaba zai zama karin bayani game da magunguna daidai da wannan alamar.