Ƙari alama CA 19-9. Analysis na CA 19-9: kullum da kuma sa'ad da ya tashe

Ƙari alama CA 19-9 ne mai high kwayoyin nauyi glycoprotein. An samar da Kwayoyin a cikin epithelium na narkewa kamar tsarin. Kamar yadda wani bincike Hanyar amfani immunohemilyuminestsentny analysis. CA 19-9 ake dangantawa da cancerous pathologies.

janar bayanai

Don karatu da nazarin halittu abu kamar yadda aka yi amfani da venous jini. CA 19-9 - wani tasiri ƙari alama. Its definition da ake amfani a cikin ganewar asali, sa idanu da kuma farkon ganewa na metastasis a ciki, pancreas, hanta, hanjinsu (ciwon da kuma dubura). CA 19-9 matakan ƙara a kusan dukkan marasa lafiya da gastrointestinal marurai, musamman na pancreas. Samar da Kwayoyin a marurai, glycoprotein shiga cikin tsari dabam dabam. Kiyaye da kuma kimantawa da abun ciki, da masana su sami zarafin su bi hanya na cutar. Analysis na CA19-9, da kudi na wanda a da lafiya mutum ba fiye da 10 U / ml ba a yi amfani da farko ganewar asali.

Mene ne pancreatic ciwon daji? summary

Wannan oncological cutar zuwa ranar da aka kunshe a cikin jerin mafi hatsari pathologies. Game da 90% da marasa lafiya mutu a cikin shekarar farko ta cutar. A lokacin da lifiya a 80% da marasa lafiya samu da m ko yanki metastases. Masana sun sanyã wannan yafi tare da boye kan Pathology. Haka kuma cutar sau da yawa ya ɓadda a matsayin na kullum kumburi tafiyar matakai a kwarara zone hepatopancreatoduodenal gabobin (cholelithiasis, cholecystitis, na kullum pancreatitis). A dangane da wannan bukatar da wuri-wuri don gudanar da wani bambanci ganewar asali, ban da gaban malignancy. Wannan, bi da bi, za ta zaɓa mafi inganci warkewa dabarun daga wadannan kullum yanayi.

Antigen CA 19-9. maida hankali

A ciwon daji na pancreas akwai wani babban matakin glycoprotein. Analysis na CA19-9, wanda yana dauke da sama mulki, na bukatar da ganewa na sankara, kimantawa yiwuwar resection. A wani taro na fiye da 1000 U / ml neoplasm zaton operable kawai 5% da marasa lafiya. Idan abun ciki shi ne kasa da nuna Figures, da ƙari yawanci za a iya cire shi ba. Duk da haka, bayan da baki na tsawon daya zuwa watanni bakwai, akwai hadarin na komawa. Ƙari alama CA 19-9 ne na biyu a muhimmanci bayan da alama CEA ga ganowa malignancy a ciki. Bugu da kari, nazarin kara high kwayoyin nauyi glycoprotein sanya alpha-fetoprotein a cikin bincike da kuma saka idanu na lura da hanta ciwon daji, biliary fili da kuma mafitsara.

karuwa da

Dagagge matakan da glycoprotein za a iya lura a kan wani bango na daban-daban kumburi da kirki pathologies a cikin hanta da kuma narkewa kamar tsarin (har zuwa 500, amma yawanci zuwa 100 U / ml), da kuma cystic fibrosis. A cikin farko idan maida hankali ne ta ƙara a 12% da marasa lafiya. A kalla matakin a wannan - ba fiye da 45 U / ml. Glycoprotein excreted a cikin bile. A wannan batun, wani cholestasis iya a tare da wani karuwa a da abun ciki. A irin haka ne wajibi ne a gudanar da bincike a lokaci guda GGT (gamma-glutamattransferazy) da kuma alkaline phosphatase. Karuwan taro kuma za a iya lura a wani bango na sauran localizing marurai (a colorectal ciwon daji, ovarian ciwon daji), hanta da cutar (cirrhosis, hepatitis).

Rashi ko rage matakin

Masana sun lura cewa, al'ada maida hankali ba ya ware gaban ciwon daji a cikin pancreas. A wannan yanayin, shi za a iya bincikar lafiya farkon mataki cuta a lokacin da matakin ya ba tukuna ya lokaci da tashi. A binciken a marasa lafiya karbar magani, ragewan da abun ciki na glycoprotein iya nuna inganci na warkewa shisshigi.

Wanne bukatar bincike

A gwajin for ƙari alama CA 19-9 ake bukata wajen saka idanu da tasiri na warkewa shisshigi ga pancreatic ciwon daji, kazalika da farkon ganewa na cuta komawa. A binciken da damar da bambanci ganewar asali malignancy tare da wasu cututtuka (msl, pancreatitis). Nuna alama CA 19-9 nuna Yaduwar m tsari, gaban ciwon daji a bango na m metastases da cutar.

A wasu lokuta, da sanya nazari

A gwajin for ƙari alama CA 19-9 bada shawarar ga bayyanuwar bayyanar cututtuka da ciwon daji na pancreas: tashin zuciya, zafi a ciki, jaundice, nauyi asara. Lokaci da Lokaci sanya nazari marasa lafiya da wani da farko babban taro na glycoprotein da karbar magani. Analysis shawarar mutanen da ake zargin ciwon daji a cikin gall mafitsara ko biliary fili, hanta, ciki ko ciwon. Research haka gudanar a hade tare da sauran gwaje-gwaje.

kwafi

A reference darajar zangon wadda dole ne matakin na antigen - 0-35 U / ml. Kamar yadda riga aka ambata a sama, da babban taro na glycoprotein nuna gaban malignancy a cikin pancreas. A mafi girma da abun ciki, da karin ci-gaba mataki cuta. Wuce kima matakan nuna ƙari metastasis.

muhimmanci bayanai

Test abun ciki dauke glycoprotein ne da muhimmanci musamman a farkon ganewa na metastatic yaduwar ciwon daji a cikin pancreas. Game 7-10% na mutanen da ba su da gene cewa encodes babban kwayoyin nauyi glycoprotein. Haka kuma, a cikin jiki akwai wata kwayoyin damar haduwa da antigen CA 19-9. Saboda haka, ko da a cikin ganewar asali malignancy matakin na glycoprotein ba a gano a cikin magani.

Don ƙarin bayani,

Kafin ka bada gudumawar jini, masana bayar da shawarar ba hayaki for rabin awa. A bincike da darajar da gwajin ƙaruwa, yayin da nazari a kan CEA. Bugu da kari zuwa saitin da mafi m ganewar asali da kuma dace saduwa dole magani shawarar gwaje-gwaje domin CA 72-4, total bilirubin, CA 242. Laboratory nazarin sanya wannan masana kamar hepatologist, internist, likita ko oncologist.

ƙarshe

Masana sun lura cewa a yau ciwon daji a cikin pancreas ne ƙara na kowa a cikin marasa lafiya bayan shekaru 30. Wannan Pathology ne daya sosai talauci gano da kuma talauci amenable ga far. A wannan batun, mafi mahimmanci gwaje-gwaje ake bukata don gane ta. Abin baƙin ciki, da binciken na antigen taro ba za a iya amfani na farko ganewar asali da cutar mataki. Duk da haka, wannan gwajin ne mafi mahimmanci kuma m for kimantawa da tasiri na magani, ganewa na farkon matakai na metastasis na ciwon daji. Lalle, kwararre a cikin binciken amfani da sakamakon daban-daban bincike hanyoyin. Bugu da kari a dakin gwaje-gwaje, da haƙuri da aka nada da kuma instrumental bincike. A mafi m na wadannan ne yanzu da Amurka. A gudanar da masu sana'a za su iya gane ƙari size daga biyu santimita. Don fayyace wannan size, wuri, da kuma yaduwar malignancy rubũta a CT scan. Amfani da wannan hanya, ana iya gano daga ƙari size uku santimita. Ya kamata a ce cewa hali na CT an haɗa don a samar da wasu kashi na X-haskoki. Saboda haka, wannan binciken da aka ba a yi akai-akai ko kamar yadda prophylaxis. Kadan danniya a kan haƙuri ta jiki samar da wani MRI. Amma irin wannan bincike da aka ba za'ayi wa mutane da suke da wani ƙarfe implants. Dukkan wadannan bincike da matakan, tare da jini gwaje-gwaje iya gane farkon matakai na ciwon daji ci gaba ko metastasis a cikin pancreas.