Salmonella tifimurium - pathogen, ganewar asali, magani

Salmonella kwayoyin tifimurium da aka sani a magani kamar yadda Salmonella enterica serovar typhimurium. Yana da wani gram-korau, sanda-dimbin yawa kwayoyin da flagella (m gashi-kamar Tsarin), da wanda kwayoyin motsa.

Mai suna kwayoyin - babban dalilin ci abinci mai guba (salmonellosis) a cikin mutane. Yana kamu shi ne mafi sau da yawa naman alade, da kaji da nama, qwai. Dabbobi kuma iya aika da shi.

Yadda Salmonella suna classified?

Saboda haka, muna da sha'awar a tifimurium Salmonella - causative wakili na mai hatsari cutar kamar Salmonella. Irin Salmonella enterica aka hada 6 subspecies:

• enterica.
• salamae.
• arizonae.
• diarizonae.
• houtenae.
• indica.

Enterica subspecies enterica hada Salmonella wadannan serogroups:

• A (paratyphi A).
• B (tsere, typhimurium, agona, heidelberg).
• C (cholerae suis, Newport, muenchen, virchowinfantis).
• D (Dublin, enteritidis, Rostock, sendai, typhi).
• E (anatum).

Tifimurium Salmonella (S. typhimurium)

View enterica aka dauke su pathogenic to mutane da dabbobi, kazalika da tsuntsaye, amma mafi muhimmanci ne kawai kaɗan daga gare su zuwa ga mutane. Kuma mafi yawan lokuta na salmonellosis lissafta ga S. typhimurium.

Mutane da yawa damuwa Salmonella resistant zuwa zamani maganin rigakafi, da kuma haka ake rarraba duk duniya. Saboda haka, nosocomial salmonellosis - mai tsanani matsalar a wannan lokacin. A 80% na lokuta da causative wakili na nosocomial (nosocomial) salmonellosis - shi ne S. typhimurium.

pathogenicity dalilai

Kuma hatsarin ga ce hanyar da cutar pathogenicity wadannan dalilai:

• Flagella samar da m motsi na kananan kwayoyin.
• Kwantena na bacteria da aka kare daga phagocytes. Kuma saboda kasawarsa na phagocytosis tasowa sepsis.

• mamayar shigar azzakari cikin farji alama da ke sa shi matsala-free ga zurfin-kwance nama.
• Saboda da kyau mannewa (makala), don samar da fibrils, pectins, LP-saccharide hadaddun, da kwayoyin wanda aka kiyaye shi a cikin jiki.
• Exotoxins (kayayyakin da ta aiki) ulla zawo tare da m dehydration, m jijiyoyin bugun gini permeability.
• Endotoxin tsaye daga kan hallakaswa phagocytosis. Yana lipopolysaccharide hadaddun cewa suranta su buguwa. Platelet tari a cikin kananan capillaries take kaiwa zuwa kumburi, akwai DIC. A mugunya Na kuma CL rage m tsoka, kuma Ya ƙãra hanji motility.

Yadda resistant kwayoyin?

Salmonella tifimurium da juriya ga daban-daban muhalli dalilai:

1. Watanni uku da suka da aka adana a dakin da zazzabi alaka abubuwa.
2. Shekaru hudu da adana a bushe faeces dabbobi.
3. Watanni biyar - a cikin ruwa, rabin shekara - in kiwo kayayyakin da nama, a kan eggshells - har zuwa wata daya.
4. Mutuwa ya auku ne kawai a 100 ° C. A nama kayayyakin da high jure zafin jiki ƙaruwa (a laban nama ya kamata a Boiled sa'o'i biyu, amma sai yana da hadari). Da taimakon salting da kuma shan taba kada ku kashe Salmonella.
5. Wannan pathogen iya tsayayya da zazzabi rage zuwa -80 ° C.
6. Shi ne resistant zuwa UV haske.
7. A disinfectant ake bukata don yin tsayayya da minti 20 ya kashe kwayoyin cuta.

Annobar cutar da salmonellosis faru lura a cikin bazara, sau da yawa bincikar lafiya a matasa da yara saboda imperfections na rigakafi da tsarin.

Pathology daukar kwayar cutar ta hanyar alimentary tuntubar da lamba-Baiti. Af, yana da muhimmanci a cikin yin amfani da qwai a kula da irin da furotin da kuma gwaiduwa. Lokacin da turbidity, hemorrhage, rududdugaggu wari, da kwai ne m kamuwa. Ya kamata a jefar, da jita-jita zuba chlorine hannuwa kamar yadda suka rike. Sabulu a cikin wadannan lokuta ba ya taimaka.

Winter flash, high mace-mace da kuma lambar-Baiti watsa inji na juriyar faruwa dalilai da kuma saboda gaskiyar cewa, tanadin abinci da aka Karkasa.

shiryawa zamani

A shiryawa zamani yana daga shida zuwa takwas hours a rana, amma mafi sau da yawa na farko bayyanar cututtuka bayyana a cikin ta farko yini ɗaya ko biyu bayan cin wani gurbata samfurin.

A take ruwa-gishiri metabolism saboda zawo, stool zama na ruwa, frothy, smelly, tare da ganye, reminiscent na "fadama laka." Tare da mita har zuwa sau goma a rana, domin a mako ko fiye.

A cuta ya fara sa samun abinci, ne halin da rauni, lethargy, m ciki zafi (epigastric da umbilicus). A ciki mai raɗaɗi ne a kan palpation, audible tsãwa da kuma busa kula.

Salmonella tifimurium - Laboratory kanikancin

A ganewar asali ta shafa da wadannan sigogi:

• ya karu erythrocyte sedimentation kudi.
• leukocytes tare da wani motsi zuwa hagu.

Pathogen gano daga nazarin halittu ruwaye (tumbi, jini, fitsari, sashin jiki shafa) da kuma m kayayyakin bacteriological Hanyar. A karshe sakamakon shi ne, kamar yadda mai mulkin, ta shirya da rana ta biyar.

Bayan kamuwa da cuta da Salmonella tifimurium, da wadannan cututtuka:

• zazzabi.
• jin sanyi.
• m zawo.
• amai.

magani

Wannan cuta na iya zama m, a jariri, da tsofaffi, da kuma a cikin marasa lafiya tare da rage rigakafi. Kuma wannan hatsari Salmonella tifimurium.

Jiyya ne cewa amfani da maganin rigakafi da kuma rehydration. Har ila yau rubũta antispasmodics, enzyme shirye-shirye, sorbents, antidiarrheals. "Table №4» nuna rage cin abinci.

Far kamata a gudanar karkashin tsauraran likita dubawa, kuma resuscitative matakan amfani a mai tsanani lokuta. Na sorbents ga detoxification na jiki shi ne bu mai kyau don amfani da wadannan kwayoyi:

• "Enterosgel".
• "Liferana".
• kunna carbon.
• "Smecta".
• "Enterodeza".

Tare da m m amai shi ne m kira motar asibiti domin hana dehydration. A haƙuri ne yawanci wajabta "Regidron". Karuwan yawan zafin jiki da rage-rage antipyretics.

Active da Salmonella Salmonella enterica maganin rigakafi

Antibacterial jamiái aiki da Salmonella Salmonella enterica, yi "furazolidone" "Ciprofloxacin", "Rifaximin", "nifuroxazide". Amma za su iya kawai rubũta likita, daukana up mutum sashi da kuma shan la'akari da yanayin haƙuri, kamu da Salmonella tifimurium.