Prednisolone: umarnin don amfani, da pharmacological Properties

Saki form "Prednisolone" miyagun ƙwayoyi: m magani siffofin - maganin shafawa.

Farmsvoystva

Prednisolone ne dehydrogenated analogue na hydrocortisone. Antiallergic, antiinflammatory, antiexudative da antipruritic sakamako a lokacin da amfani da topically maganin shafawa "prednisolone" wa'azi sa wani karu a cikin samuwar, saki da kuma aiki na kumburi shiga tsakani (kinin, a histamine, lysosomal enzymes, prostaglandins). Har ila yau hana cell hijirarsa zuwa kumburi cibiyar rage-rage vasodilation kuma Ya ƙãra jijiyoyin bugun gini permeability da ya auku a kumburi. Rage exudation ne saboda da vasoconstrictor mataki na "Prednisolone" miyagun ƙwayoyi. Manual nuna cewa da miyagun ƙwayoyi ne an immunosuppressive sakamako da inhibiting da mataki na antigen-antibody hadaddun da tara a kan garun jini da kuma ne dalilin rashin lafiyan vasculitis. Da miyagun ƙwayoyi damuarn da mataki na macrophages, cytokines, manufa Kwayoyin cewa sa da ci gaban rashin lafiyan dauki irin m dermatitis. Kamar wancan sensitized T-lymphocytes da kuma macrophages ba zai iya samun damar yin amfani da manufa Kwayoyin.

Pharmacokinetics

Lokacin da aikace-aikace na man ƙanshi "Prednisolone" tunawa da aiki abu ne a cikin jini. A jini jini prednisolone babba sashi ba shi da related to albumin da transcortin. Biotransformation prednisolone faruwa da hadawan abu da iskar shaka, yafi a cikin hanta, inda glucuronidation ko sulfation auku oxidized siffofin. A cikin irin metabolites excreted a cikin fitsari da kuma tumbi, wani ɓangare - a wani unmodified jihar. Prednisolone wuce ta placental shãmaki a kananan yawa, shi za a iya samu a cikin ƙirjinka madara na mata.

Prednisolone: shaidar

Da miyagun ƙwayoyi da ake amfani a lokuta da:

- rashin lafiyan da irritant lamba dermatitis,

- eczema,

- atopic dermatitis,

- seborrheic dermatitis,

- psoriasis.

Prednisolone: umurci

A maganin shafawa ne amfani da rauni site ko'ina 1-3 sau / rana. Duration na lura ne ya sa ta yanayin da cutar da kuma yawanci yana for 8-14 kwana. Maganin shafawa a lura da yara duration na magani ya kamata a rage zuwa 3-7 kwanaki, tun da yaro ta jiki ne mafi kula da miyagun ƙwayoyi "Prednisolone". Umarni ya bada shawarar bari Warming, kayyade da kuma occlusive dressings.

Features na aikace-aikace

A tsawon lokaci da magani tare da maganin shafawa kada ta kasance fiye da 14 days a domin su hana yiwu illa daga yin amfani da "Prednisolone" miyagun ƙwayoyi. Umarni ya furta da su bi kawai a karkashin likita dubawa.

illa

Yawancin lokaci da miyagun ƙwayoyi ne da jure. Da wuya, musamman bayan shafe tsawon amfani, na iya haifar da itching, kona abin mamaki, erythema. A wasu marasa lafiya da illa iya bayyana a matsayin folliculitis, hypertrichosis, perioral dermatitis, rashin lafiyan halayen ga magani aka gyara. The sama cututtuka ba su bukatar magani da kuma sauri cire a ƙarshe na aikace-aikace na da miyagun ƙwayoyi. Ya kamata a tuna cewa aikace-aikace na wani maganin shafawa zuwa shafa fata da kuma dogon lokacin da amfani (musamman a cikin shan kashi na manyan yankunan da fata) na iya bayyana gefen sakamakon wani tsari yanayi.

Hulɗarka tare da sauran kwayoyi

Prednisolone yana da dukiya ya inganta anticoagulant sakamako na anticoagulants. Yana qara da yiwuwar zubar da jini yayin da shan salicylates. Yana qara da alama na electrolyte metabolism cuta da concomitant gwamnatin diuretics. Akwai girma hadarin yawan guba a lokacin da yin amfani da cardiac glycosides. Rage hypoglycemic antidiabetic sakamako da kuma rage-rage na antibacterial aiki na rifampicin. Ba da shawarar don amfani a tare da antacids.

contraindications

Jiyya "Prednisolone" shafawa wa'azi da aka haramta a cikin:

- hypersensitivity.

- kwayan, kwayar, fungal fata raunuka.

- tarin fuka, syphilis, fata marurai, ciki, kowa kuraje da kuma m kuraje.

yawan abin sama

Lokuta da yawan abin sama ne ba a sani ba.

ajiya yanayi

Kiyaye a kan jerin B, a 5-15ºS. Shiryayye rai - 2 years. A ranar da shiryayye rai ba don amfani.

yanayi na lantarki

Takardar sayen magani.