BIMF - New Technology tsaya a nan Tsufa

A kimiyya da fasaha kashi

Hamzari The manufa na nazarin halittu-mutum

Medical fasahar (BIMF)

Lokacin rubuta wannan sashe, matsalar da fuskantar da marubucin: abin da harshe da kuma a cikin abin da sharuddan yin gabatar. Aka yanke shawarar bayyana

mafi kawai, saboda BIMF hada da wani iri-iri na fasahar zamani, kuma wata sanarwa a kan wani "daya masana'antu harshe" iya yin m da kuma bayani ga sauran kwararru.

Samarwa fasahar BIMF muhimmanci da farko a matsayin warkewa dabara saboda daruruwan iri bincike hanyoyin ba warke babu daya.

1. Basic ka'idodin da su zargi.

Ya kamata a lura, a cikin ra'ayi, babban maki a search for

wani mutum na akida, da kuma hanyar magani. Ga wadanda suka san shi za su iya zama m, amma har yanzu kana tuna yadda shi ya kasance.

Kafin zuwan maganin rigakafi, sa'an nan a lõkacin da suka bayyana bil'adama

fatan samu da kuma amfani da "mafi kyau" yana nufin cewa,

Yana da jũna game da za a bude. Kowane mutum na da aka jiran wasu irin "sihiri harsashi"

(Ehrlich). Bugu da ari, a kan ganewa na da ake dasu juriya ga

maganin rigakafi, asar, sai murna ba hanya zuwa despondency. A daidai wannan lokaci masana kimiyya

sanya na biyu "nutsewa" a ganye magani da kuma halitta sinadaran

(Mummy, shark guringuntsi, Chaga, kudade ganye) a wani ƙoƙari na samun mai ban mamaki na halitta

yana nufin. A ci gaba da jinsi da kuma proteomics gano antioxidants,

ganewa na da yawa ilimin-aiki abubuwa, su rabe, da ci gaban m sinadaran pharmacotherapy da jũna nuna hanyar fita daga rushewar msar tambayar da m pharmacology da kuma magani. Hakika, da nasarorin samu a cikin mazan jiya magani daga wasu cututtuka, babu wanda ya musanta. Duk da haka, wadannan nasarorin ba su isa ba.

Deciphering da mutum genome bada kadan. mutuwa kira kwayoyi ba warkar da cutar kanjamau. Ko 30-35 dubu genes na mutum genome samar da kusan m zabin da kuma haduwa, ko da a rubuce ba zai yiwu ba ga lissafi da nazarin gene aiki kuma su hulda zabin.

Dalilin rashin cin nasara a lura da ciwon daji da kuma sauran cututtuka da yake a polymorphism (canzawa) kwayoyin gina jiki Biochemistry. A'a, ko da mafi kyau, bisa ga halittawa, da miyagun ƙwayoyi ba da gaske samun zuwa 100% a cikin "Biochemistry" na jiki na wani musamman haƙuri, saboda "da kansa Biochemistry" da "nasu halittar jini", musamman gare shi. Ta yaya suka bambanta daga mutum zuwa mutum? Amsar ita ce: har zuwa mutane ne daban-daban kowanne daga juna. Akwai yunkurin yin amfani da fetal, tayi far, kuma a karshe kara Kwayoyin - "kowa da kowa" nazarin halittu (cell, nama) far.

A a layi daya, duk da haka, shi ne ci gaban da kanka magani.

Haka ya faru a wani ɓaɓɓake. Amfani da gabatarwar nasa jini (autohemotherapy), da aka kafa homeopathy (bi da kamar) (Sama'ila Hahnemann), Usul da aka yi amfani da zabin da personalization

homoeopathic magunguna (tsananin akayi daban-daban), kuma a cikin yi da wasu iri kwayoyi (nosodes, renozody) da abu (da waxannan cututtukan nama) na mutum marasa lafiya. Shirya da mutum biologics abu (secretions, jini) da marasa lafiya (Hanyar L. Yaschenko, Crimea, Ukraine). Yau, misali, wasu kasashen waje Biofirm (kamfanin «Antigenics Corporation») ne Ya sanya daga wani cancerous ƙari nama da marasa lafiya domin wannan marasa lafiya - anti-ciwon daji maganin abu don dalilai na magani (immunotherapy) da nasu ciwon daji.

Saboda haka, za mu iya bambanta biyu main trends a cikin mazan jiya magani.

Farko.

Medicine kokarin samun zuwa cikin hanyar (etiology), ko a ci gaba da cutar inji (pathogenesis). Haka kuma, alal misali, maganin rigakafi, an dauke m fada cikin dalilin: halakar pathogens a cikin jiki, msl, a cutar. Antihypertensive kwayoyi yawanci aiki a kan daban-daban sunadaran (pathogenesis) na hauhawar jini.

Lura, duk da haka, musamman himiolecheniya. Ko da kullum cututtuka, a mafi yawan lokuta, magunguna ana amfani da "gaggawa" agaji. Watau amfani da kwayoyi za su kula da a mafi kyau - kwanaki.

Kwayoyi mukaddashin shekaru da watanni, babu. Ko da yake, kamar yadda suka faɗa, duk

kullum cututtuka suna lalacewa ta hanyar matalauta salon zabi, cewa shi ne,

tsawon lokaci da kuma m cututtuka da kuma zullumi - wani al'amari na sa'a.

A lura da kullum cututtuka ƙoƙari ya tsawanta miyagun ƙwayoyi mataki, kamar ake ji da su depositing ko da ake ji daban-daban "na fasaha sia nanocontainers" ko tsawo siffofin (msl, Bitsillin). Bugu da kari, sau da yawa a kullum cututtuka magunguna gushe aiki, kuma suna da a kai a kai canza: canza "sunadarai" na jiki na haƙuri ko jinsi, da abun da ke ciki antigenic na pathogen. Ko, da farko magunguna ba aiki saboda wani kayyade ko biochemical polymorphism (bambancin) da kwayoyin da marasa lafiya da kuma pathogens.

Wannan shi ne, a cikin wannan tsarin kula da magani, da kwayoyi amfani kama ko shafa kawai wani sashi na pathological tsari, kuma bisa ga hali su ne gaba daya dan hanya zuwa ga jiki, tun lokacin da aka samar da sinadaran hanyoyin.

Na biyu Trend.

Shi ne a fili a bayyane personification, amma dangane da m ka'idojin. A homeopathy, a mafi kyau, shi a tsare "type" na haƙuri, wata iyaka jerin homeopathic magunguna. Autohemotherapy (lura da nasa jini) bai samar da ake so sakamako: ba kawai a cikin jini don magani da kuma ba duka share, misali, da yiwuwa na gabatar da wani haƙuri ta mallaka jini sepsis. Kuma yana da gaske daya mai gefe gani yiwuwa na masana'antu da kuma aikace-aikace na nazarin halittu kayayyakin sanya daga nasu, modified cuta, watau pathologically ƙẽƙasasshen nama. A lissafi, lokacin da wannan ne yake aikata, duk da haka, a jiki ta rigakafi da martani. Amma zai iya amsa mai iko counter-hari na rigakafi da tsarin mayalwaci, riga m da cutar, kamar ciwon daji?

Rigima inganci na mura magani, da rashin yiwuwar samun alluran yaki da cutar kanjamau da kuma ciwon daji hade da biyu da kwayoyin bambancin da pathogens, kuma daga kwayoyin rashin zaman lafiya da kwayoyin na haƙuri sel (heterogeneity). Yadda "kama" da sãɓãwar launukansa pathological yanayin canza pathogenesis, canza halittar jini na cuta aiwatar da hanzari canza halittar jini na pathological kwayoyin (da ake kira "pathomorphosis" Kwayoyin da nama a cikin daji, HIV, heterogeneity na AIDS)? Yadda za a kama abin da aka canja hanzari? As "daskararre" irin magungunan da su bi sosai da sauri canza pathological tsari ko wani abu da ake sosai da sauri genetically modified?

Bugu da ƙari, kamar yadda aka samu: da mutum genome ƙunshi duk aka sani kwayoyin, ciki har da pathogenic protozoa (pathogens). (A cikin wannan "m" juyin halitta). Yadda za a dakatar da rashin zaman lafiya da nasu DNA a ciwon daji da kuma AIDS? Abin da idan a farkon na DNA da cutar kadai, sa'an nan shi ne daban-daban? A cikin wancan, ya ta'allaka da gazawar da samar da allurar da ciwon daji da kuma AIDS. Yadda za ka ƙirƙiri wani nazarin halittu makamai (biobronyu) na musamman hatsari cututtuka?

Akwai na uku, mai maimaituwa Trend - biologics, Biotech - warkewa magani, interferons, insulins, pirogenal (samu daga typhoid), prodigiozan, bifidus, lacto-bacterins, da dai sauransu .. Duk wadannan allotropic, cewa an samu daga waje Kwayoyin kuma (micro) kwayoyin.

Alurar riga kafi ba zai magance nan, kamar yadda shi ne yawanci, kuma Fãce alaka rigakafin.

Lokacin amfani maye far (jini musanya, da furotin da shirye-shirye ...), babban kamfani na likitoci ne magani don daidai da daidai "a layin" tare da Biochemistry na jiki: ba zai wani gefen effects, amma zai fi da kuma warke. Saboda haka, a lokacin da allura, ta amfani da daban-daban samfurori for "karfinsu" tãre da mãsu haƙuri ta jiki. maye far kwayoyi ne ma ba ilimin mutum.

Manufar magani domin ciwon daji da kuma AIDS - ya kashe genetically modified Kwayoyin, sa'an nan ba da damar ci gaban da wuraren waha (na sprouts da iyalansu) na al'ada Kwayoyin.

Yau yunkurin naúrar daidaita Genetics mallaka (autosomal) ga curing dalilai kerarre na marasa lafiya Kwayoyin tare da matsakaiciyar jan a vitrum (-tube fasahar) ta amfani da kwayoyin injiniya dabaru (canja wurin da gene shuffling) ta amfani da plasmids, ƙwayoyin cuta, "vectors", da dai sauransu Irin nasarorin suna fadin, da kuma matsaloli da kuma matsaloli na jinsi da aka sani kuma karaya.

Kalmomi biyu game da kalaman itatuwa aure. A cikin ra'ayi, akwai matsala a samar da aperiodic sigina daga al'ada DNA, saboda E.Shredinger - DNA aperiodic. Ya zuwa yanzu, to mu ilmi, ba an kafa janareta iya samar da aperiodic sakonni a fadin kamu da electromagnetic bakan. Kalaman far tsananin ilimin kasuwanci motocin, shi ne "kaddarance".

Wannan yana da nisa, a cikin wani roundabout hanyar magani da kuma pharmacology, ta amfani, kamar yadda mai mulkin, kasashen waje abubuwa, kwayoyin, micro-kwayoyin da dan hanya jinsi - ƙoƙarin normalize halittar jini da kuma Biochemistry na jiki na da wani rashin lafiya mutum, cewa shi ne - in warkar da shi.

A lura da kara Kwayoyin amfani da wani ke ko naka Kwayoyin. Babban matsalar da magani daga kara Kwayoyin, a cikin ra'ayi, ne murdiya na warkewa sakamako saboda da undecidability na wannan lokacin: 1. babu wani yiwuwar a duk lokuta a samar da niyya bayarwa na kara Kwayoyin a cikin so sashin jiki, nama ko mayar da hankali; 2. babu wani yiwuwar don samar da kowane su somatic cell a kara cell. 3. shiga jini kara Kwayoyin suna rarraba da ka a ko'ina cikin jiki. 4. babu tabbacin na samun kara Kwayoyin da hakkin wuri. 5. ba hasashen sakamakon da jiyya saboda da bazuwar rarraba kara Kwayoyin. 6. A warkewa sakamako na kara Kwayoyin aka lura kawai a cikin sosai kusa da filin daga wuri na ta wuri. 7. tsari effects a kan dukan jiki daga kufan kara Kwayoyin aka ba musamman da aka nuna, saboda har yanzu gida mataki na kara Kwayoyin da kuma gwada yawa, sãɓã wa jũnamai saboda: adadin somatic (jiki) da kuma yawan Kwayoyin gudanar kara Kwayoyin.

Kwanan nan, mun kuma lura da Trend daga cikin kunkuntar selectivity daga mataki halitta da kwayoyi - su versatility - to su mataki kai tsaye a kan da yawa manufa.

A dukkan lokuta, mu bi da kuma warkar da wani mutum yayi kokarin amfani da irin wannan illa da kuma magani, daga abin da, kyakkyawan, bisa al'ada ya (haƙuri) duk mutum metabolism (homeostasis) da / ko duk da jinsi, wanda ke nufin wani koma kiwon lafiya.

Saboda haka, ra'ayin mazan jiya warkewa (pharmacological) m na fallasa da dukan kwayoyin (live dukan tsarin) da kuma duk da sunadaran, ciki har da kwayoyin, - ba a buɗe, da kuma daidai da ba a amfani da su.

Kuma a karshe, na karshe daya. Mutane daya-daya facts kwatsam (maras wata-wata) m magani marasa lafiya da mataki 4 ciwon daji bayar da shawarar guda: akwai wani koma ga al'ada mutum a duk matsayin kungiya: kwayoyin, subcellular, salula, nama, sashin jiki, da dai sauransu Wannan shi ne, a koma ga al'ada, "yin amfani da" dokoki - shi ne na ƙarshe burin warkar da kuma magani. Saboda haka me ya sa ba amfani domin lura da "al'ada"?

An fahimci cewa dawo da kuma komawa jiki zuwa al'ada, to kiwon lafiya Can da ya kamata a yi kai tsaye ta amfani da wannan 'yan qasar nazarin halittu, biochemical, kwayoyin bayanai na nasu lafiya ta jiki (somatic) Kwayoyin qazanta da cikakken nazarin halittu bayanai ta amfani da totipotent Kwayoyin.

Babu bukatar zama likita ya san cewa idan wani mutum da aka haife kuma ya rayu har zuwa ya shekara ba tare da wani bayyane cututtuka da kuma matsalolin da cewa zai iya zama nuni da ta kayyade cuta, shi ne da tsoho, wanda shi ne wata ila don mutum halittar jini ya asali al'ada. Saboda haka, za ka iya amfani da shi a BIMF jiki Kwayoyin ga manufar waraka da tanadi da kiwon lafiya na mutum.

Duk da haka, domin ganewar asali na wani "al'ada" Jihar somatic Kwayoyin za a iya amfani da a matsayin jerawa (karatu na) genome (tsada hanya, m, m don amfani a sa idanu da genome) da kuma "bincikowa da genome ga alamomi na janar Pathology" - histone sunadaran (samuwa, amma ba kasa m hanyar tantance jihar da genome, musamman - a tsauri ci gaban da Rasha -. Paponov marubucin Vladimir D. et al, Medical Auren Research cibiyar raguna, Moscow) ..

Goals - ci gaba da akida, da kuma kimiyya tushe na jiki magani da kuma lura dangane da wasu fiye da sinadaran pharmacotherapy ka'idojin (hanyoyin) - aka saita a matsayin fifiko a cikin dacewa sassan na Rasha Fasaha Development Shirin na tsawon shekara ta 2007 - 2011, rene ta Rasha gwamnatin. Wadannan manufofin ake samu ta hanyar mu.

Don kwanan wata, domin dalilai na m (ta halitta ra'ayi) da kuma tare da mafi hadari magani - duniya ta manyan Pharmaceutical da kuma fasahar binciken halittu ta far amfani da matsakaicin achievable na "individualization" na selection da kuma samar da magunguna.

Lalle ne, akwai ƙwãya daga gaskiya a gaskiyar cewa a cikin yi da miyagun ƙwayoyi masana'antun, da aka jera a kasa, domin kare kanka da "duniya" personalization, individualization, biotechnological dabaru an shafe antigenic kungiyar, musamman Properties na kwayoyi na nazarin halittu abubuwa da cewa yin up wadannan guda da kwayoyi, game da shi, sake saita (baje) su antigenicity , allogeneic (nazarin halittu foreignness). Kamar haka ne a haɗe zuwa "universality" don aikawa zuwa "duka" da irin wannan kwayoyi.

Wannan tsarin kula da sarrafa daga medicaments ne sosai kamar yin amfani da kara Kwayoyin a biotherapy, da kuma "zeroed" a gabar su heterogeneity (waje), kuma da ita - "kowa da kowa" umarnin don amfani.

Saboda haka, Jamus hadaddun shirye-shirye «diddige» da kuma / ko Italian «Oti» (Officine Terapie m) dauke da (ko yi nufin amfani da)

homeo (kama) + + Organotropona maye (canzawa) sinadaran.

(Dubi., Bi da bi, misali, Catalog na shirye-shirye na Jamus kamfanin "Biologishe Haylmittel diddige GmbH" Janar Medicine 2011-2012, JSC "alpha leporis», 2011. www.heel.com) (Quick Reference "Compendium" na magunguna damuwa Oti www. otiomeopatici.com).

Kuma, har a karshe, magunguna dauke da pharmacologically aiki abubuwa - Organic-da nama takamaiman-cell bioregulators (peptides, da dai sauransu) Daga cikin daban-daban gabobin da kuma sel (zuciya, kwakwalwa, pineal gland shine yake, kananan hanji, babban hanji, erythrocytes, hanta, ovaries, Lymph nodes, mammary gland shine yake, tsoka Kwayoyin, koda, bargo, pancreas, pituitary, huhu da kuma bronchus, ciki, prostate, saifa, na yara thymus, thyroid, mahaifa, golaye, fetal tayi nama), bayar a yau «vitOrgan» kamfanin ( Jamus).

Miƙa wadannan kwayoyi, «vitOrgan» shelar kamar yadda zai yiwu ainihin individualization, personalization miyagun ƙwayoyi daukan hotuna. Wadannan kwayoyi sanya daga yadudduka (duk da haka) dabbobi tashe a cikin tsabta yanayi da kuma tsabtace ciyarwa.

Yau, da haukan Russia a fili canja zuwa naturalization a matsayin abinci da magani. All ne m iya zama domin amfani da yin amfani da Chemical Pharmacology da kwayoyi. Mutane bayyana fuskar yanayi, fifita halitta magunguna da kuma abinci, kamar yadda tsayayya wa chemically hada da m.

Ta duk na sama, ya kamata a bayyana m na duniya Pharmaceutical da kuma fasahar binciken halittu domin personalization, individualization na nazarin halittu magunguna da kansu da kuma individualization (Bio) fasahar domin su samar.

A little more lokaci, da kuma "za isa ga duk" abin magunguna kamata sami kuma bi da su ta hanyar da nazarin halittu-mutum kiwon lafiya na'urorin fasahar zamani (BIMF).

Ga wanda sa'an nan zai zama wani fifiko na wannan fasahar?

Hanyoyin da yin amfani da

Bio-likita mutum na'urorin fasahar zamani (BIMF)

domin lura ko personification misali pharmaceutical kwayoyi,

ba tare da watsuwar qwarewar.

cirewa da dama da lafiya rai dauke da kwayar nuclei, domin dalilai na curing jiki daga cuta, daga jiki na haƙuri.

Comment.

Hakar daga Kwayoyin da kwayoyin iya kwashe cin zali (ta hanyar wani incision, huda) da kuma noninvasive (zubar da jini) Hanyar (misali, gilashin ko bugu a kan salula scraper). A wani rashin lafiya jiki, idan ba wani gaji kwayoyin cuta da 100% kashi duk Kwayoyin, ne ko da yaushe akwai ya ci gaba da lafiya, tare da m halittar jini somatic (jiki) Kwayoyin. Idan dole, cirewa daga wani sel da kwayoyin, ciki har da sighting dauka daga kyallen takarda ko gabobin, kamar sarrafawa damar. Ga dalilai na BIMF cirewa da kuma amfani da al'ada Kwayoyin dauke da wani tsakiya (eukaryotic) da kwasfa a diploid (full, biyu) sa na chromosomes, cewa shi ne, da cikakken genome - da yuwuwar totipotent Kwayoyin. Kamar yadda ya bayyana ta zamani halittar jini, shi ne totipotent Kwayoyin dauke da cikakken bayani (ciki har da kwayoyin) na jiki daga abin da suka kasance kãma: daga yiwuwar totipotent Kwayoyin iya tasowa a dukan kwayoyin (dolly tumaki).

Help.

Tsananin magana - jiki (somatic) Kwayoyin, tsokoki na, ba yau kira totipotent, da kuma bambancin. A totipotent kira kawai tayi kara Kwayoyin. Ko da jawo pluripotent kara cell (IPS) an kira pluripotent ...

Na asali da muhimmanci shine cewa da diploid somatic (jiki) Kwayoyin kawo cikakken m totipotency.

Tare da cirewa Kwayoyin a wani musamman hanya (fasahar) suna nemi da ayyuka a sakamakon wanda fallasa, ya zama ruwan dare da kuma cire duk abinda ke ciki na wani daga cikin wadannan Kwayoyin, ko duk nazarin halittu bayanai daga wadannan Kwayoyin. A wannan yanayin, idan ya cancanta, da cell irin (nama m) Kwayoyin iya zama tilas ko neutralized ko adana, ko modified. Sa'an nan dukan salula abinda ke ciki, ko kuma nazarin halittu bayani game da salon salula abinda ke ciki halitta (ninka) musamman hanya a cikin wani musamman matsakaici (m).

Comment.

Wannan ne mai babbar milestone a BIMF. Lokacin zalunta Kwayoyin a wannan mataki an yi amfani da matsayin da hankula da aka sani da dabaru da kuma fasahar, kazalika da musamman (gwaninta), sun ha] a guda fasaha sake zagayowar. Sel da / ko su ke ciki da ake gittar da wa, a wani kebantaccen tsari, wani sinadaran Sol-gel fasahar, micromanipulation, zauna da girma a cikin dakin gwaje-gwaje cell al'adu, injin effects, cryotherapy, tsoma, ta amfani da ginannun kayan da micro-nanolayers da pores ... Su ne batun wasu hada duk matakai na fasaha.

A musamman hali da kuma irin rubanyawar nazarin halittu bayanai a yau ne, misali, PCR fasahar (Polymerase Chain Reaction), ya bayyana a rubuce a 1971 da kuma m bada shawarwari a 1983.

Tare da PCR, kamar yadda aka sani, na faruwa multiplexing (multiplication, multiplication, maimaita kwashe, karawa) na nazarin halittu bayani a cikin wani nau'i na DNA (ta da wani ɓaɓɓake).

The m dauke da ninka a cikin shi nazarin halittu abu, tsarin bayani game da lafiya cell, cewa shi ne - a kan salula kiwon lafiya - An gabatar a cikin jikin mutum haƙuri, wanda ya na sirri lafiya somatic Kwayoyin aka asali janye.

Comment.

A matsakaici dauke da wani ilimin-mutum bayanai, a lokacin da gudanar da wani tabbacin ya kai da kuma shiga cikin duk somatic Kwayoyin. Akwai za haka a fallasa sau daya duk somatic Kwayoyin. Ka tuna: wuce haddi ilimin-keɓaɓɓen bayani a cikin goyon bayan bayar da ta multiplication (multiplication). Alal misali, da nazarin halittu bayanai ne cirewa daga sel 10 iya multiplexed miliyoyin ko biliyoyin kofe. Saboda haka, mataki da wannan bayani za a assimilated da mataki na miliyoyin da biliyoyin wadannan Kwayoyin!

Saboda haka, haƙuri ta jiki na'am da a wuce haddi da kansa (tsananin ilimin mutum!) Bayani game da al'adar kiwon lafiya. Rarar kiwon lafiya bayanai a jikinka tabbas ne kõmãwa ne (lura) mayar da pathological bayanai da kuma matakai, watau - daidai a kuma warkar da haƙuri. Rarar nasu nazarin halittu kiwon lafiya bayanai za su kara da cika fuska a sama al'ada a sau da jiki ta jure wani tasiri.

Abũbuwan amfãni, kuma siffofin BIMF

(Bio-mutum likita fasahar).

BIMF ne daya da kuma hadawa, watakila duk wani nau'i na yau m fasahar - nano-, bio-, cryogenic, injin, cell, Sol-gel, pharma, jan, mikroinstrumentalnye - kawai dacewa da aikace-aikace na live tsarin da kuma a lokaci guda ya ƙunshi wani unifying - da "karo na biyar da rabi". Used da jini da fasaha, high-zazzabi injin kayan aiki don aiki da kuma masana'antu na kida da dakin gwaje-gwaje glassware.

A fasahar ba ka damar mai da (warkewarta) kamar yadda dukan jiki, da kuma ta raba gabobin da kyallen takarda - da ya dace canje-canje a cikin tsari da fasaha.

Bayani.

BIMF Hanyar iya samu nasarar ci gaba data kasance fasahar yau girma autologous gabobin da kyallen takarda.

BIMF Hanyar ma sa ya yiwu don amfani da shi ga manufar tsayawa ko revertirovaniya (baya) shekaru da alaka da canje-canje nan da nan a ko'ina cikin dukan kwayoyin.

BIMF Hanyar damar akayi daban-daban sirranta misali Pharmaceutical shirye-shirye, "daidaitawa, canza su tsarin" a karkashin Biochemistry da kwayoyin ko haƙuri Kwayoyin kuma tsokoki, cikinsa da na sarari conformation da miyagun ƙwayoyi kwayoyin ba zai canza ta empirical dabara. (Kada ku halattar da hakkin miyagun ƙwayoyi masana'antun). Ta Canza cikakken BIMF Pharmaceutical shiri ne dace da haƙuri da jiki, sabili da haka za su kara da warkewa sakamako da kuma a lokaci guda minimizing su m, ko mai guba effects, kasancewa konformirovannym akayi daban-daban.

Bayani.

BIMF Wannan amfani da za su zama "zinariya" tsakiyar - jayayya tsakanin miyagun ƙwayoyi masana'antun - farmfirm (farmbiznesa) a daya hannun, da kuma BIMF - zalla mutum "bezhimicheskoy" miyagun ƙwayoyi da fasaha, a daya hannun, a cikin abin da wani magani sanya daga igredientov nasu kwayoyin. Bayan duk, da fasahar gaske gusar BIMF amfani da magani daga sinadaran pharmacology, watau sa shi dole ba pharmaceutical sinadaran masana'antu kamar yadda irin wannan. Duk da haka, irin wannan m sanarwa, da kuma ba za ka iya yi ta amfani da daidaitattun BIMF da kuma sinadaran shirye-shirye a hade, don bunkasa warkewa sakamako na hadin gwiwa.

An sani cewa misali, da m bitamin C (ascorbic acid), da ciwon guda empirical dabara a matsayin kwayoyin yana da 28 na sarari jeri (isomers), daya kadai na wanda yana da nazarin halittu aiki a cikin mutane. Sarari fuskantarwa ne sau da yawa a key dalilin da ineffectiveness miyagun ƙwayoyi mataki. Kuma kamar yadda wani tabbaci: shi ne wani canji na sarari conformation na gina jiki ke haifar da prion cututtuka (spongiform encephalopathy = = mahaukaci saniya cuta, scrapie , da dai sauransu ..), Wanda a yau ba su sani ba - yadda za mu bi. (Prions - gina jiki jinsunan).

All sanya zuwa kwanan magunguna da na sarari tsarin, sabili da haka iya spatially konformirovatsya.

Domin da hanyar BIMF ba muhimmanci magunguna farko na sarari tsarin: shi zai konformirovana daidai da individuality na Biochemistry da kwayoyin (ko Kwayoyin) na mai haƙuri.

BIMF hanya ne na musamman a cewa a cikin aiwatar da watsi da haddasawa (etiology) da cutar da kuma ginshikai na cutar (pathogenesis), kamar yadda su ne kawai m (sai dai gaji cututtuka).

A Hanyar ma ya sa ya yiwu in warkar prion kuma a fili wasu gaji kwayoyin cututtuka, kuma a karshen harka - idan iyaye suna da rai da kuma / ko probands ( 'yan'uwa maza ko mata) na mai haƙuri.

A Hanyar rubanyawar BIMF za a fuskanci da nazarin halittu bayani a kan duk sunadaran da kuma a kan dukan abinda ke ciki na cell - aka sani, kuma ba a sani ba zuwa ranar.

BIMF damar da ake ji lokacin da bambanci bayanai daga wannan haƙuri ga nasarar warkar, duk da kwayoyin bambancin da pathogens ko sel (nama) da kwayoyin.

BIMF ba ka damar aiki tare da Kwayoyin 'matsalar' sashin jiki da kuma nama: duka biyu dabam da kuma tare a lokaci daya - kamar yadda ya faru a cikin jiki. A hanyar sa ya yiwu a yi watsi da, cewa shi ne, ba a taba da ake kira matsala na Hayflick (iyakance yawan mitosis zuwa 50 ga somatic Kwayoyin, telomeres matsaloli telomerase), kamar yadda ya samu da ake so sakamakon a aiwatar da fasaha za a iya amfani da BIMF Kwayoyin kawai "matasa" ƙarni - watau Kwayoyin daga "na farko, farkon" mitoses.

A BIMF mu ba amfani: Halitta Engineering (hanyoyin da shuffling kuma gene canja wurin), cloning kwayoyin, radiation da sauran environmentally cutarwa ko datti fasaha. Halittu watsi a cikin yanayi a lokacin BIMF m kawai watsi daga handwashing da sabulu, ko jiki.

Hanyoyin da yin amfani da

Bio-likita mutum na'urorin fasahar zamani (BIMF)

domin dalilai na tsayawa tsufa (anti-tsufa), ba tare da bayyana gwaninta.

A takaice fasaha ne da wannan: daga matasa jiki Kwayoyin suna cirewa. Idan haihuwa kwayoyin, ta Kwayoyin, bayan hakar, sanya a cikin wani dakin gwaje-gwaje cell al'adu a vitro inda suka riɓaɓɓanya, rejuvenated. Daga dauka ko samu dukan matasa Kwayoyin cirewa nazarin halittu bayanai da aka canjawa wuri zuwa ga matsakaici inda shi ninka (halitta). Sa'an nan, da m wannan "matasa" nazarin halittu bayanai da aka gabatar a haddi a cikin jiki da kuma shiga a cikin dukan Kwayoyin. Saboda haka, jiki sami fiye da kima da kansa nazarin halittu "matasa" bayanai, wanda zai kai ga a kalla daina tsufa, ko rejuvenation. (Taimake mafi cikakken bayanin.)

Saboda haka, a lokacin da amfani da, a dukan kwayoyin BIMF cimma tsananin mutum (na kanka, na sirri):

1. magani.

2. A anti-tsufa (rejuvenation) ko kayyade nazarin halittu shekaru.

3. personification misali kantin pharmaceutical magunguna.

4. biobronya: sirri total rigakafin (karawa a sau dukkan m nazarin halittu Properties da kwayoyin).

A cikin aikace-aikace na da waɗannan kimiyoyi duk a kan wanda kuma wannan mutum, mun samu wannan mutum, amma shi ne a cikin wani sabon hanya! A lokaci guda, ya zauna da kansa, cewa yake - zai zama guda mutum, wannan hali, individuality.

Hakazalika, BIMF aikin za a iya raba wannan sub-4, wanda za a kiyaye uniform akai - BIMF. Kuma, ba shakka, duk hudu yankunan da za a iya da za'ayi a cikin guda cibiyar BIMF.

Hanyar Amfani (Hanyar)

Bio-likita mutum na'urorin fasahar zamani (BIMF)

domin dalilai na tsayawa tsufa (anti-tsufa), ba tare da bayyana gwaninta.

A takaice fasaha ne da wannan: daga matasa jiki Kwayoyin suna cirewa. Idan haihuwa kwayoyin, ta Kwayoyin, bayan hakar, sanya a cikin wani dakin gwaje-gwaje cell al'adu a vitro inda suka riɓaɓɓanya, rejuvenated. Daga dauka ko samu dukan matasa Kwayoyin cirewa nazarin halittu bayanai da aka canjawa wuri zuwa ga matsakaici inda shi ninka (halitta). Sa'an nan, da m wannan "matasa" nazarin halittu bayanai da aka gabatar a haddi a cikin wani shekaru (da haihuwa), cikin jiki da kuma shiga a cikin dukan Kwayoyin. Saboda haka, jiki sami fiye da kima da kansa nazarin halittu "matasa" bayanai, wanda zai kai ga a kalla daina tsufa, ko rejuvenation.

Comment.

Hakar daga Kwayoyin da kwayoyin iya kwashe cin zali (ta hanyar wani incision, huda) da kuma noninvasive (zubar da jini) Hanyar (misali, gilashin ko bugu a kan salula scraper). Darussa matasa Kwayoyin ko samu matasa Kwayoyin iya sanya don ajiya a cikin Cryobank har suka yi amfani. cryo-ajiya Kwayoyin samar da su kiyayewa, wato, kusan - agelessness. Idan dole, jiki dawo da na'urar da wani Kwayoyin, ciki har da sighting dauka daga kyallen takarda ko gabobin, kamar real-lokaci damar idan da ake bukata a cikin wani m sighting ko gida "zamu juya" da gabobin ko kyallen takarda. Ga dalilai na BIMF cirewa da kuma amfani da al'ada Kwayoyin dauke da wani tsakiya (eukaryotic) da kwasfa a diploid (full, biyu) sa na chromosomes, cewa shi ne, da cikakken genome - totipotent Kwayoyin. Kamar yadda ya bayyana ta zamani halittar jini, shi ne totipotent Kwayoyin dauke da cikakken bayani (ciki har da kwayoyin) na jiki daga abin da suka kasance kãma: daga totipotent Kwayoyin suna iya ci gaba da wani dukan kwayoyin. Wannan shi ne, duk da nazarin halittu da bukatun da kwayoyin a matsayin dukan, a matsayin mai rai tsarin ana bayar da ko za a iya bayar da potencies (damar) totipotent Kwayoyin. Wannan shi ne dalilin da ya sa m totipotent Kwayoyin suna amfani da BIMF.

Tare da matasa ko rejuvenated Kwayoyin a wani musamman hanya (fasahar) suna nemi da ayyuka a sakamakon wanda fallasa, ya zama ruwan dare da kuma cire duk abinda ke ciki na wani daga cikin wadannan Kwayoyin, ko duk nazarin halittu bayanai daga wadannan Kwayoyin. A wannan yanayin, idan ya cancanta, da cell irin (nama m) Kwayoyin iya zama tilas ko neutralized ko adana, ko modified. Sa'an nan dukan salula abinda ke ciki, ko kuma nazarin halittu bayani game da salon salula abinda ke ciki halitta (ninka) musamman hanya a cikin wani musamman matsakaici (m).

Comment.

Wannan ne mai babbar milestone a BIMF. Lokacin zalunta Kwayoyin a wannan mataki an yi amfani da matsayin da hankula da aka sani da dabaru da kuma fasahar, kazalika da musamman (gwaninta), sun ha] a guda fasaha sake zagayowar. Kwayoyin da / ko su ke ciki da ake gittar, daga oda, a sinadaran Sol-gel fasahar, micromanipulation, zauna ko girma a dakin gwaje-gwaje cell al'adu injin tsoma, cryotherapy, tsoma, ta amfani da ginannun kayan da micro-nanolayers da pores ... wasu aiyuka ga su hada duk matakai na fasaha.

A musamman hali da kuma irin rubanyawar nazarin halittu bayanai a yau ne, misali, PCR fasahar (Polymerase Chain Reaction), ya bayyana a rubuce a 1971 da kuma m bada shawarwari a 1983.

Tare da PCR, kamar yadda aka sani, na faruwa multiplexing (multiplication, multiplication, maimaita kwashe, karawa) na nazarin halittu bayani a cikin wani nau'i na DNA (ta da wani ɓaɓɓake).

The m dauke da ninka a cikin shi abu nazarin halittu, da tsarin bayani game da wani matashi lafiya cell, cewa an - a kan salula abinda ke ciki m ga tantanin halitta na matasa - An gabatar a cikin jikin mutum haƙuri (abokin ciniki), a cikin abin da ya na sirri lafiya somatic Kwayoyin aka asali janye.

Comment.

Kalmar "matasa cell" yana nufin da yanayin da ke ciki daga cikin sel m zuwa ta matasa, da cewa shi ne - karo na farko da farkon mitosis. A matsakaici dauke da wani ilimin-mutum bayanai, a lokacin da gudanar da wani tabbacin ya kai da kuma shiga cikin duk somatic Kwayoyin. Akwai za haka a fallasa sau daya duk somatic Kwayoyin. Ka tuna: wuce haddi ilimin-keɓaɓɓen bayani a cikin goyon bayan bayar da ta multiplication (multiplication). Alal misali, da nazarin halittu bayanai da aka cirewa daga 10 matasa (ko rejuvenated) Kwayoyin za a iya multiplexed har zuwa miliyoyin ko biliyoyin kofe. Saboda haka, mataki da wannan bayani za a assimilated da mataki na miliyoyin da biliyoyin wadannan Kwayoyin!

Janye lafiya somatic Kwayoyin tabbatar da rashin yiwuwar mai haɗari canja wurin da cuta a cikin rejuvenating jiki, da aiwatar da manufar tsayawa BIMF tsufa, ko rejuvenation.

Saboda haka, jiki na haƙuri zai karɓi a wuce haddi da kansa (tsananin ilimin mutum!) Bayani game da your matasa jihar - da jihar ta matasa Kwayoyin. Rarar matasa da kuma bayanai a cikin jiki tabbas ne dakatar da koma (lura) juyawa shekaru da alaka da canje-canje da matakai, cewa an - tsaya a nan, ko kuma rejuvenates da tsufa haƙuri.

Abũbuwan amfãni, kuma siffofin BIMF

(Bio-mutum likita fasahar)

to daina tsufa, ko rejuvenation.

BIMF ne daya da kuma hadawa, watakila duk wani nau'i na yau m fasahar - nano-, bio-, cryogenic, injin, cell, Sol-gel, pharma, jan, mikroinstrumentalnye - kawai dacewa da aikace-aikace na live tsarin da kuma a lokaci guda ya ƙunshi wani unifying - da "karo na biyar da rabi". Used da jini da fasaha, high-zazzabi injin kayan aiki don aiki da kuma masana'antu na kida da dakin gwaje-gwaje glassware.

A fasahar damar zuwa zamu juya dukan jiki, da kuma ta raba gabobin da kyallen takarda - da ya dace canje-canje a cikin tsari da fasaha.

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