Beta-blockers

Beta-blockers ana amfani da antihypertensive kwayoyi tun da farkon sittin. Tun lokacin da aka gano sakamakon farko na magani, har zuwa yau, an tabbatar da tasirin su a cikin bincike mai yawa, kuma idan aka kwatanta da tasiri na zamani.

Ana amfani da beta-blockers don rage yawan jini da kuma hana ci gaban cutar cututtukan zuciya da mace-mace. Hanyoyin aikin da suke yi na kashe su ya dogara ne akan rage yawan abin da ke cikin ƙwayar zuciya ta hanyar rage yawan ƙarfin da ƙaddamarwa. Bugu da ƙari, beta-blockers na inganta lalata maye gurbi a cikin juxtaglomerular (kusa da tantanin halitta) na'ura mai mahimmanci kuma, a cikin wannan haɗuwa, maye gurbin tasirin aiki a cikin renin-angiotensin-aldosterone da tsakiyar tsarin vasomotor.

Tsarin dasu na tsawon lokaci zai iya haifar da raguwa na juriya na jijiyoyin jiki (na yau da kullum), saboda ƙwarewar ƙwararrun barodeceptors da kuma samar da prostacyclin (prostaglandins) a cikin bango.

Beta-blockers, amfani dasu a daidai sakon, suna da irin wannan sakamako na hypotensive. Cikakken maganin rigakafi yana tasowa cikin makonni biyu zuwa hudu. Dangane da babban liyafa, akwai ƙwayar "sakewa". Don yin rigakafi, ba a cire magungunan nan da nan ba, amma sannu-sannu aka rage kashi a cikin goma zuwa goma sha huɗu.

Sakamakon tsarin kwayoyi, musamman, wanda ba zaɓaɓɓe ba, na iya haifar da ci gaban ƙananan cututtuka da ƙwayar cutar zuciya.

Na farko da kungiyar hada da cuta a cikin Psycho-wani tunanin bango (ciki, barci cuta, da dai sauransu), na numfashi bayyanar cututtuka (bronchospasm), na gefe vasoconstriction (intermittent claudication, sanyi extremities, da dai sauransu), tsoka rauni, rashin ƙarfi. Sauran cututtukan lakaran ƙananan suna lalacewa na aikin rena, sakamakon lalacewar jini a kodan, matsalolin lipid da carbohydrate metabolism.

Kungiyar bayyanar zuciya ta hada da:

• Rashin aikin wanke zuciya, tare da alamun rashin lafiya;
• Blockade (mai zaman kansa, sinoatrial) na zuciya da bradycardia;
• Ƙaddamar da hypotension game da tushen cutar ƙin jini mai karuwa;
• Hanyar antiarrhythmic.

Ya kamata a lura da cewa bambancin da ke cikin kantunan da ake amfani da su na pharmacological na blockers ya sa ya yiwu don zaɓar wata magani mai kyau mafi kusan kowane hali. Wannan kuma yana la'akari da jurewar jiyya, ƙananan haɗarin tasiri, sakamako na tsawon lokaci da yanayin yanayin halin asibiti.

Gayyadadden beta-blockers a matsayin farfadowa daya zai sa ya yiwu a cimma daidaituwa na BP a cikin tsari na 40-50% na marasa lafiya da hauhawar jini. Idan aka kwatanta da tasiri ga marasa lafiya a cikin matasa, matsakaicin shekaru da tsufa, sakamakon yana da ƙananan ƙarancin tsofaffi. Yin amfani da diyartic thiazide a hade tare da beta-blockcker na iya kawar da bambance-bambance. Saboda haka, tasiri na farfadowa tare da wannan haɓaka ya karu zuwa 78-80%.

Beta-blockers zuwa yi wa angina zauna a wuri na musamman. Da wannan cututtukan, ana amfani da kwayoyi irin su Anaprilin (Obsidan), Sotalol, Atenolol, Concor, Monotard.

Ayyukan waɗannan magunguna sune nufin rage yawan karfin jini da "jinkirin rage" zuciya. Yin amfani da kowace miyagun ƙwayoyi ya kamata a zaɓa ta hanyar likita.

Kwayoyi suna contraindicated a fuka, na kullum obstructive na huhu cututtuka, atrioventricular block na biyu ko na uku mataki. Ba da shawarar yin amfani da beta-blockers a illa glucose haƙuri, na gefe jijiya cuta, da 'yan wasa da kuma jiki aiki mutane.