Pituitary wada: haddasawa, cututtuka, magani na cutar

Pituitary wada (wada) - wata cuta da halin girma retardation da kuma wani jiki cin cuta saboda mugunya na agara lobe da pituitary somatotropin - girma hormone. Yana da wannan hormone ne ke da alhakin aiwatar da cell division a cikin jikin mutum.

Iri pituitary wada

Bisa ga etiological factor pituitary wada (23.0 MB) code ne:

1. Primary, ci gaba na abin da ya auku a sakamakon pituitary cuta, da kuma yadda wani sakamako, rage girma hormone matakan.
2. Hypothalamic, ci gaban wanda yake shi ne saboda wani karu a matakin na hypothalamic sakewa hormones, tsara don suna da wani sakamako a kan pituitary gland shine yake.
3. Tare da nama da juriya ga ci gaban hormone. Its ci gaba ne saboda da rashin rabe a manufa kyallen takarda don amsa da kyau zuwa ga mataki na hormone.

etiopathogenesis

Hanyar pituitary wada iya zama wani kashi na pituitary: ƙari (meningioma, craniopharyngioma, chromophobe adenoma), rauni, mai guba, dauke da kwayar cutar lalacewa mezhutochno- pituitary yankin ko dysregulation na pituitary gland shine yake da hypothalamus. Duk da haka, mafi cuta siffofin da dangantaka da wani kayyade type.

A mafi girma rarraba yana pangipopituitarnaya wada, wanda o ƙarin za a gaji da yafi recessive irin. Akwai jita-jitar cewa akwai iri biyu na watsa siffofin da wannan cuta - autosomal kuma ta hanyar X-chromosome. Tare da mugunya girma hormone cuta a cikin wannan nau'i na wada da ya auku mafi sau da yawa a cikin rashin lafiya secretions na thyroid-haramta motsa hormone da gonadotropins.

Ƙasa da ƙasa da damuwa mugunya ACTH. Kamar yadda aka nuna ta hanyar aikin nazarin da sakewa hormone marasa lafiya (nazari kuma hada da roba girma hormone-sakewa hormone, kunsha na 29, 40 da kuma 44 amino acid sharan), da mafi yawan wadannan marasa lafiya da hypothalamic cuta, da kuma underdevelopment na agara pituitary gland shine yake riga secondary fasalin. Primary Pathology na pituitary kai tsaye ya faru da wuya.
Akwai marasa lafiya da ciwon rauni na tsakiya m tsarin saboda rashin oxygen, msl, a mahara ciki.

Tsananta illa ta jiki ci gaba da wada Can dalilai kamar rashin kuma unbalanced abinci mai gina jiki, da furotin da halin da kasawa, tutiya da sauran ma'adanai, illa muhalli dalilai, gaban concomitant somatic cututtuka.

cututtuka

Backlog na 'yan adam girma yi da kuma ta jiki ci gaba daga talakawan matsayin - cewa an bayyana pituitary wada. A hoto a kasa ya nuna bayyanar cututtuka da cutar.

Bugu da ƙari, da jariri yana da wata al'ada jiki nauyi da kuma tsawon. Stunting mafi yawa ana gani kawai a cikin 2-4 shekara na rayuwa: da girma kudi ga wani m yaro na wannan shekara ne 7-8 cm a kowace shekara, alhãli kuwa yara da pituitary wada girma da wani talakawan of 2-3 cm Kafin gabatarwar hormonal far. Dwarf dauke girma ga mata kasa da 120 cm ga maza - kasa da 130 cm.

The asibiti hoto na pituitary wada

Yawancin lokaci sosai sauki domin sanin kasancewar wani sabon abu da aka sani da pituitary wada. Mẽne ne da kuma yadda shi rinjayar da mutum ta bayyanar, da muka bayyana su daki-daki a kasa.

A jikin haƙuri yana da pituitary wada halayyar rabbai na yara. Akwai wani bata lokaci ba, a lokacin da ossification na kwarangwal, kazalika da bata lokaci ba a canji na hakora, matalauta ci gaban da aka gyara na musculoskeletal tsarin da kuma subcutaneous mai, pallor, rashin ruwa, da kuma fata wrinkling, wani lokacin akwai haddi mai a kan kirji, cinyoyinsa da ciki. Mafi sau da yawa, akwai wani sakandare hairiness.

Ephippium a 70-75% da marasa lafiya ba ya canja a size (sauran - rage), amma halittarsa yayi dace da yara da haihuwa kuma yana da wani nau'i na tsaye m. A cikin hali na pituitary marurai ephippium lura da karin ƙasƙanci daga ganuwar ta.

Asarar gonadotropic pituitary aiki tsokani wani bata lokaci ba na jima'i cin sau da yawa ba tare da Pathology. Matsayin mai mulkin, babu sakandare jima'i halaye. Male marasa lafiya suna rage a kwatanta da shekaru na kullum azzakari da prostate, underdeveloped Kwalatai (Scrotum). Mafi yawa daga cikin mace wahala daga cutar, ba su yin haila, kuma suna da underdeveloped ƙirãza.

Intelligence rinjaye da marasa lafiya ne kiyaye, ban kasance marasa lafiya tare da ganewar asali "pituitary wada", pathogenesis na wanda shi ne saboda da kwayoyin kwakwalwa lalacewar ƙari ko traumatic yanayi.
Halayyar da cuta ne splanhnomikriya - raguwa a size of ciki gabobin, jijiya hypotension, muffled zuciya sauti, m hypotension, bradycardia. Kila wani buɗi na sakandare hypothyroidism da hypocorticoidism.

Ganewar asali da pituitary wada

Yawancin lokaci ganewar asali "wada" a manya bayan shakka. Anamnesis data da kuma hadadden dakin gwaje-gwaje, da na asibiti da kuma radiographic jarrabawa ne hormonal dalilin ganewar asali "pituitary wada", code MB 10 23.0.

Evaluation na 'yan adam girma

Don gane asali, bambance da kuma gano cuta kamar yadda pituitary wada, cututtuka, da kuma magani domin sanin daidai, ya yi ilmin lissafi kimantawa adam girma. Domin ta kimantawa, ban da cikakkar size na jiki, ƙayyade girma karanci wakiltar bambanci tsakanin darajar haƙuri tsawo da kuma talakawan rate m zuwa ta zamani da kuma jima'i. girma shekaru kamar yadda matching da dabi'u na haƙuri girma da wasu nagartacce. darajar da bisa al'ada sabawa:
N = P - PCP / δ,
inda P - tsawo daga cikin haƙuri.
PCP - da talakawan darajar al'ada girma ga wakilin na jinsi da shekaru.
δ - karkacewa daga PCP.
A manufa darajar N <3 ne hankula ga irin wannan cututtuka kamar pituitary wada, wada, N> 3 - don gigantism. Wannan nuna alama za a iya sarrafa, da kuma tantance masu kuzarin kawo cikas na ci gaba.

Ganewar asali da pituitary wada a yara

Pituitary wada a yara yana bukatar wani karin m tsarin kula da ganewar asali daga cutar, kamar yadda shi ne sau da yawa na asibiti hoto ne m. A ganewar asali da aka bayar na tsawon watanni shida zuwa shekara. A wannan lokaci da yaro ne karkashin kula, an wajabta restorative magani ba tare da hormone far, abinci mai gina jiki tare da m dabba gina jiki, da kayan lambu da 'ya'yan itatuwa, alli, phosphorus, da kuma bitamin A da kuma D. Rashin karkashin wadannan yanayi isa canjawa cikin sharuddan girma da kuma ta jiki ci gaba ne dalilin irin wannan nazarin, kamar:

• jini girma hormone.
• girman kwanyar radiography don gane Pathology a zagayayyen kwanya.
• X-haskoki daga cikin kirji, ƙashi na daga hannun kuma wuyan hannaye, wadda ta bayyana kashi shekaru na yaro.
• MRI.
• lissafta tomography.

Bisa ga wadannan karatu zai iya gano dalilin da cutar da kuma zuwa fara hormone far.

kwantar da hankali

Lokacin da diagnosing irin cututtuka kamar pituitary wada, dangane da magani gudanar zuwa adam girma hormone a cikin nau'i na intermittent warkewa darussa. A kashi na girma hormone gudanar dogara a kan tushen da abun ciki a cikin jini, kazalika da mutum haƙuri. Domin mafi alhẽri sha na hormone ci babban kashi ne advantageously da za'ayi a cikin safe hours, wanda yayi dace da physiological halaye na hormonal mugunya. Ruri daga jima'i ci gaba ne da za'ayi bayan aiwatar da rufe na ci gaba da zones da taimako na jima'i ji ba gani.

A mafi muhimmanci awo na warkewa da magani daga wada aka kuma samun marasa lafiya anabolic steroids, kwayoyi phosphorus, tutiya, alli, da kuma bitamin gidaje biostimulants, isassun abinci mai gina jiki.

Don fara jiyya shi ne bu mai kyau zuwa ga wada a 5-7 shekaru.

Canzawa far yana shekaru da dama, tare da m dubawa na da tasiri na kwayoyi riƙi da haƙuri da su maye tare da ya fi dacewa, kuma ya ƙare da kawar da Sanadin cutar. Idan ba za ka iya gyara matsalar da haƙuri da aka wajabta maye far ga rayuwa. Tare da kyau sized magani samu wani girma kudi na 8-10 cm a kowace shekara, kuma da mãsu haƙuri ba ya bambanta daga yara masu lafiya.

Shi ne m don tsayar rai da marasa lafiya da wani endocrinologist.

girma hormone magani

Saboda bayani dalla-dalla na 'yan adam girma hormone aiki a lura da wada ne kawai adam girma hormone, samar da jiki, kazalika da mannyan birai. Yadu amfani somatotropin samar da kwayan kira ta kayyade aikin injiniya ta amfani da Escherichia coli. Akwai somatotropin, wani roba da sinadaran yana nufin, amma shi ne kusan taba amfani saboda ta high kudin.

Experience ya nuna cewa dabi'u na m tasiri kashi na farko da magani lokaci dace 0.03-0.06 MG da kilogram jiki nauyi. Iyakar yadda ya dace da shan 2-4 MG sau 3 a mako. By kara guda kashi zuwa 10 MG isasshen karuwa girma sakamako da aka ba a lura, amma ya nuna m samuwar antibodies zuwa somatotropin. An muhimmanci amfani da magani na girma hormone ne ba hanzari na ossification na kwarangwal a kan bango.

A amfani da anabolic steroids

Don daya daga cikin mafi muhimmanci kayayyakin aiki, a lura da wada da dangantaka haƙuri amfani da anabolic steroids. Su mataki dogara ne a kan ruri na ci gaba da kara gina jiki kira da kara game da shi, matakin da na ciki girma hormone. Wannan magani ne da za'ayi domin shekaru da dama, kasa aiki kwayoyi aka hankali maye gurbinsu da more aiki mahadi. A nuni ga canza anabolic kwayoyi ne akan rage 2-3 shekaru ci gaban sakamako, wanda, bi da bi, yana da sakamako na kara bunkasa ci gaban. Pituitary wada ya shafi magani anabolic steroids kamar warkewa hanya tare da lokaci na sauran, daidai da rabin lokaci na jiyya. A cikin akwati nuna habituation da kuma daina karya (har zuwa 4-6 watanni). Daya harbi mai karɓa hada da daya kawai irin anabolic steroids, hada da mahara kwayoyi impractical domin bunkasa su mataki ba ya faruwa. Dosing na anabolic steroids farawa tare da m tasiri da su sauka a hankali karuwa.

Jiyya na jima'i rashin ci gaba na boys

Jiyya na jima'i rashin ci gaba na boys kamu da wada aka yi amfani da mutum chorionic gonadotropin. A amfani da wannan magani ba ya fara kafin shekaru 15, kuma sau da yawa har daga baya a rayuwa. Effect da miyagun ƙwayoyi ne da nufin a stimulating da Leydig Kwayoyin, godiya ta zuwa ga Androgenic anabolic aiki accelerates da kuma jima'i ci gaba, da kuma ci gaba. A sashi regimen da miyagun ƙwayoyi kashi ne 1000 - 1500 Iu, intramuscularly gudanar 1-2 sau a mako, biyu ko uku Darussan a kowace shekara. Idan boys 16 shekaru gani a m sakamako a kan magani na mutum chorionic gonadotropin, samar da alternating tare da kananan allurai androgens ( "Methyltestosterone" Sublingual 5-10 MG da rana). Crowning mataki na lura da namiji marasa lafiya da aka samun dogon-aiki androgen - kwayoyi "testenat", "Omnadren-250", "Sustanon-250."

Jiyya na jima'i rashin ci gaba a 'yan mata

'yan mata, magani iya fara a 16, simulating a low kashi na estrogen al'ada hailar sake zagayowar. Yana yana da za'ayi a cikin makonni uku na kowane wata. Na biyu lokaci na hailar sake zagayowar daga cikin mako guda uku za ka iya sanya chorionic gonadotrophin sashi 1000-1500 Iu samun jadawalin 3-5 sau a mako. A madadin ne kwayoyi progestin mataki ( "Progesterone," "Pregnin").

Kammala magani (a kammala al'amari na rufe na girma zones) samun Game da m jima'i hormones a warkewa allurai. Wannan shi ne zama dole domin jima'i gabobin da sakandare jima'i halaye sun kai cikakken ci gaba, don tabbatar da ya dace matakin na libido da kuma iko. Mace marasa lafiya suna wajabta hada estrogen-progestin shirye-shirye, kamar "Non-ovlon", "Infekundin", "Bisekurin", "Rigevidon".

Outlook

Photos rayuwa tare da pituitary wada dogara a kan da siffar. Idan kana da kaina da fuskantar irin wannan matsalar, kamar yadda kwayoyin pituitary wada, shi ne koya ganin an, da zai so a sake tabbata da ku - a cikin wannan harka, da hangen nesa ne m. A gaban pituitary marurai raunuka na CNS, rauni da sauransu. E., The hangen nesa dogara a kan muhimmancin da babban pathological tsari.

Godiya ga hanyoyin zamani na lura da jiki da iya aiki da kuma aiki da damar mutanen da fama da wada, ƙara muhimmanci ta tsawon kwanakinka da tsawon rayuwarsu. A lokacin aiki magani lokaci, dole za'ayi tsanaki jarrabawa na marasa lafiya duk 2-3 watanni, tabbatarwa far - jarrabawa kowane 6-12 watanni.

A farko factor a aikin yi da kuma zamantakewa karbuwa da marasa lafiya da wada ne su jiki da kuma ilimi damar. A bu mai kyau a zabi wani sana'a, ban da motsa jiki.