Latest ƙarni na anti-depressants. Antidepressants: Wanne ne mafi alhẽri? Reviews likitoci farashin

Yau, ciki rinjayar ba kawai manya amma kuma yara da kuma matasa. Wannan cuta da kuma hanyoyin da wajen magance shi kishin da yawa na gudanar da bincike da kwararru da kuma babban adadin articles da kuma littattafai. Idan muka fassara da "kimiyya" a cikin talakawa harshe, ciki - shi ne asarar ƙarfi ne, kuma so su rayu. A bayyanar cututtuka da wannan cuta ne lethargy da kullum a cikin wani mummunan yanayi, tashin hankali da gajiya, lethargy da moodiness.

Modern pharmacology yayi a magance cutar karshe tsara antidepressants. Kuma da yawa timoleptikov (kuma aka sani da jamiái, yanã tafiya da gaggãwa da ciki) ya zama a yau cewa sun yi tarayya a kuma bambanta da juna, abin da yake cikin tsarin ba da su mataki? Wadannan da sauran tambayoyi za a jawabi a samarwa labarin to your hankali.

Menene antidepressants?

Wannan magani, ta hanyar abin da za ka iya ya rage bayyanar cututtuka da kuma ko da hana ciki. Babban inji na mataki ne da nufin daidaitawa da biochemical ayyuka na mutum kwakwalwa. Jijiya Kwayoyin, da aka gyara, har abada sadarwa tare da juna ta hanyar musamman abubuwa - neurotransmitters. A cewar daya daga ka'idar, depressive cuta bayyana a lokacin da a cikin kwakwalwa saboda dalilai daban-daban, muhimmanci rage matakan matsakanci ko wani biogenic Amine: dopamine, norepinephrine ko serotonin. latest ƙarni na antidepressants, kazalika da dukan gabata ƙanananku, da gudãnar da matakin gyara a kan kwakwalwa biochemical matakai ta canza maida hankali a biogenic Amine.

Menene suka ga?

Bayan da cewa zamani antidepressants taimaka jimre da bayyanar cututtuka na ciki, sau da yawa suna amfani da su rabu da irin wannan matsaloli:

• da dama ba a sani ba asalin zafi.
• cin cuta ko barci.
• mai tsanani ko kuma gajiya asarar ƙarfi.
• nervousness ko ji na DC ƙarfin lantarki.
• bouts na nervousness ko tashin hankali.
• matsaloli maida hankali ko ambaton.

tsara antidepressants

Kafin ka yi la'akari da yadda da yawa daga kwayoyi da ciki halitta ta yau, dole mu tuna cewa antidepressants aka gano kawai a tsakiyar XX karni. Don kwanan wata, dangane da lokaci na da sabuwar dabara da kuma farkon amfani a asibiti yi, kazalika da mataki na antidepressants, shi ya yanke shawarar zuwa ware hudu zamaninsu daga wadannan kwayoyi.

Shirye-shirye na ƙarni na farko

A ƙarni na farko, bude a 50-ies karni na karshe, ya wakilta tricyclic timoleptikov cyclic mataki (TCAs). Wadannan sun hada da miyagun kwayoyi, "amitriptyline" (antidepressant, shi ne na farko daga cikin jama'a) da kuma Kalam, kazalika da "Nefazodone" kwayoyi "Anafranil" da "Melipraminum". Wadannan mahadi tabuka tarewa norepinephrine reuptake, game da shi kara ta maida hankali. Duk da haka, TCAs katange ba kawai norepinephrine (noradrenaline), amma kuma duk da wasu zo musu da hanyarsu neurotransmitters, sakamakon wani babban yawan m illa, musamman kamar kaifi karuwa a jini da kuma ya karu da zuciya rate. Kwayoyi a cikin wannan kungiyar ne quite mai guba, da kuma da alama na yawan abin sama a lokacin da yin amfani da su sosai high, wanda shi ne yasa suka kadan amfani da magani daga ciki a yau.

Bugu da ƙari, na farko tsara sun hada da ba a amfani da yau dauke da komowar hanawa na monoamine oxidase (Mao) kwayoyi - "Iproniazid", "tranylcypromine," "isocarboxazid". Su mataki dogara ne a kan hanawa daga cikin ayyuka na jijiya endings na kwakwalwa neurons, game da shi kara maida hankali serotonin da kuma norepinephrine.

Biyu-tsara kwayoyi

The biyu ƙarni, sabanin na farko, yana da wani karin zabe, amma weaker sakamako a kan neurotransmitters da neurons kansu. Yana hada tetracyclic komowar (Mao-B) da kuma reversible (Mao-A) monoamine reuptake hanawa, irin shirye-shirye gabatar a matsayin "Lerivon", "Lyudiomil", "Pirazidol" da sauransu. Saboda gaskiya cewa a liyafar akwai wani sa na wajen tsanani illa, amma kuma saboda hulda da daban-daban da kwayoyi da kuma unpredictable effects, kwayoyi na wannan kungiya suna amfani sosai da wuya. A Pharmacy wajen wuya a sami wani rukuni na antidepressants, monoamine reuptake hanawa. Amma a wasu lokuta aka sãme su a karkashin wasu iri sunayen. Saboda haka, masana sun ce, cewa da miyagun ƙwayoyi "Lyudiomil" - shi ne guda kwaya "maprotiline" price, manufacturer, da kuma kawai sauran kasar.

tsara ta uku

Modern bincikensa ya gano cewa, a cikin kwakwalwa da juyayi tsarin suna da hannu wasu 30 shiga tsakani, amma ga "ikon mallakar" na ciki a duk uku daga cikinsu: serotonin, dopamine kuma norepinephrine (noradrenaline). A tsara ta uku hada da zabe serotonin reuptake hanawa (SSRIs) wakilta irin amfani zamani antidepressants, da kwayoyi "Zoloft", "citalopram", "prozac", "Tsipraleks", "paroxetine", "Pliz" kuma da yawa wasu. Wadannan kwayoyi toshe shiga tsakani ba duk, amma daya ne kawai - serotonin. By da karfi na tasiri su ne na baya zuwa farko-tsara kwayoyi, amma illa da muhimmanci kasa fiye da na wani magabata. All SSRI kwayoyi suna tasiri da kuma ya kamata a jure kamar wancan. Duk da haka, kowannenmu jiki na da mutum halaye, kuma saboda da lambar kuma ƙarfi daga cikin illa zai zama daban-daban a cikin kowane hali. Likitoci suka ce ya fi kowa m illa na uku-ƙarni kwayoyi ne rashin barci, juwa ko jiri, tashin zuciya da kuma tashin hankali.

Shin SSRIs quite tsada. Saboda haka, a fairly sanannun da kuma yadu used medicament "citalopram" darajar a Pharmacy, dangane da iri, ta hanyar da aka samar, za a iya bambanta daga 870 zuwa 2000 rubles.

Fourth-tsara antidepressants

Wadannan magunguna dauka da dangantaka SIOZSiN kungiyar (zabe serotonin reuptake hanawa da kuma norepinephrine). Waɗannan su ne latest ƙarni na antidepressants, kamar yadda kwayoyi "Cymbalta", "Milnacipran", "Remeron", "Effexor" cewa toshe kama da norepinephrine, kuma serotonin. Kwayoyi "Zyban" da "Wellbutrin" Ba hulɗa tare da serotonin, kuma dopamine, kuma norepinephrine riƙe. Ci gaban da magunguna da suke danganawa da kungiyar, ya fara ne kawai a cikin tsakiyar 90-ies karni na karshe, kuma a kowace shekara akwai karin sababbin kwayoyi.

Doctors ba zai iya ce babu wata tantama cewa a cikin wannan kungiya akwai mafi kyau anti-depressant, shi ne bisa manufa ba zai yiwu ba, kamar yadda na lura da daban-daban iri depressive cuta magunguna suna zaba akayi daban-daban, shan la'akari da halaye na kowane haƙuri ta kiwon lafiya.

Popular zamani timoleptiki

Sane da muhimmancin da tasiri na wannan kungiyar da kwayoyi a kan m tsarin, shi dole ne a tuna cewa duk zai yiwu - biyu tabbatacce kuma korau - sakamakon zai iya hango ko hasashen da neutralize kawai a horar da m - likita. Shan la'akari duk mutum halaye da kuma gane asali, shi ne likitan zai iya designate daidai antidepressants, wanda zai iya taimako mafi kyau a cikin musamman yanayin, tare da kadan illa. A cikin akwati a lokacin da shan wajabta magunguna da wani matsaloli, shi ne likitan iya daidaita ko canza magani regimen. Yau mafi practitioners bayar da shawarar cewa marasa lafiya da depressive cuta shirye-shirye daga cikin rukuni na zabe serotonin reuptake hanawa da kuma noradrenaline tasiri tasiri wanda aka tabbatar a yi. Irin wannan medicaments matsayin "milnacipran" "juyi" ( "fluoxetine"), "duloxetine", "Velaksin" ( "venlafaxine") - ya fi na kowa da kuma yadu amfani da na karshe ƙarni antidepressants. Ka yi la'akari da mafi m da magani daga depressive cuta timoleptiki.

"Flukosetin" magani

Wannan magani ne daya daga cikin na farko wakilan da SSRI kungiyar, shi hadawa biyu antidepressant kuma stimulant effects. Medicine "juyi", kuma aka sani da anti-depressant "Fluoxetine", na taimaka rage tashin hankali da kuma tashin hankali, ta kawar da tsoron da kuma inganta yanayi. A mafi inganci yin amfani da shi, bisa ga likitoci, psychotherapists, a lokuta da asthenic ciki tare da kula ba, kuma ciki mai sãɓãwar launukansa a mai tsanani, kuma m-na kullum cuta. Yana amfani da wannan magani a lura da bulimia. Antidepressant "Fluoxetine" da aka fara rijista a 1974 a Amurka, da kuma a cikin shekaru goma, sai ya tafi da fari a tallace-tallace a Birtaniya, kawai a karkashin wani daban-daban cinikayya sunan - nufin "Prozac". A Rasha, wannan magani ne yadu used da yawa clinicians bayar da shawarar cewa shi an wajabta, ga marasa lafiya, ko generics a daban-daban depressive jihohi.

Drug "Paroxetine"

Wannan shi ne mafi iko da sakamakon wani wakilin kungiyar na zabe mai hanawa, mai zabe serotonin reuptake, fiye amfani da magani na tashin hankali cuta da kuma ciki. Yau, da kwayoyi, da aiki sashi na wanda paroxetine, kyakkyawa da yawa. Wannan Rasha shirye-shiryen "Adepress" daga "Veropharm" magani "pliz" by Croatian kamfanonin na Pliva, Hungarian kwayoyi "Reksetin" by Gedeon Richter da yawa wasu. Duk yadda nazyvatsya magani "Paroxetine", reviews na shi a duka marasa lafiya da kuma likitoci domin mafi yawan bangare positive.

Drug "Wellbutrin"

Fi sani da "Zyban" ko "NouSmok". The aiki sashi na dukan uku kwayoyi ne bupropion hydrochloride, bayar da tasu gudunmuwar da karuwa a cikin adadin dopamine kuma norepinephrine a cikin kwakwalwa. Magunguna da wannan aiki sashi ba kawai taimaka bayyanar cututtuka na ciki, amma kuma taimaki cin nasara da wani tunanin sakamakon nicotine janye. Wannan magani inganta yanayi da kuma qara yadda ya dace. Feedback daga waɗanda suka samu kawar da nicotine buri ta hanyar yin amfani da irin wannan kwayoyi a matsayin "Wellbutrin", "NouSmok" da "Zyban", magana game da babban inganci na wadannan kwayoyi a cikin tsawon quitting.

"Cymbalta" magani

A shirye-shiryen da na huɗu-tsara antidepressants ne mai hanawa na reuptake na norepinephrine da serotonin, lokaci guda dauke da fitar da kadan kãmun dopamine. Da miyagun ƙwayoyi aiki abu ne duloxetine yana da wani m high, idan aka kwatanta da sauran antidepressant mataki gudun. A ra'ayi na biyu likitoci da marasa lafiya, mai bayyanannen antidepressive sakamako aka bayyana da karshen na farko - farkon mako na biyu na liyafar. Bugu da kari, wannan magani ne daban-daban uniformity na mataki kuma a ko'ina cikin lokaci na aikace-aikace. Duk da haka, akwai wani rukuni na marasa lafiya, a cikin ra'ayi da cewa sakamakon wannan magani idan suka faru, yana da matukar rauni. Kamar yadda aka ambata riga, da mutum halaye na biochemical halayen haifar da gaskiyar cewa a musamman magani wajabta ta likita, ba zai iya samar da sa ran sakamakon.

Nawa?

Yau ne quite wuya magana game da kwayoyi farashin. Wannan shi ne saboda gaskiyar cewa kudin kasuwar ne sosai m, da kuma sabo-sabo antidepressants, domin mafi yawan bangare zo mana daga kasashen waje kera, da farashin da ake ba a Tarayyar Turai. Wannan shi ne dalilin da ya sa a cikin tebur a kasa nuna wa m da kuma iyakar farashin a rubles, saboda su kawai ba za a iya kaddarance. Sashe na daga cikin kwayoyi da shiga a baya sayar ko a tsohon farashin, yayin da sabon masu zuwa ne yafi tsada.

Idan ka duba tebur a hankali, za ka lura da cewa shi rasa na biyu-ƙarni kwayoyi, wato MAOIs (monoamine reuptake hanawa). Wannan ba wani kuskure. The abu ne cewa wadannan antidepressants da yawa m illa da kuma incompatibility da yawa kwayoyi ba su kusan amfani a kasashen Turai. A Amurka da wuya amfani da "isocarboxazid" magunguna "Ugenelzin" da "tranylcypromine," kuma a kasar mu - da miyagun ƙwayoyi "Nialamide". Duk na sama magunguna suna samuwa ne kawai a karkashin kulawa da shafi tunanin mutum kiwon lafiya kwararru.

Wannan tebur a fili ya nuna cewa "classic" tricyclic antidepressants farashin muhimmanci ƙananan fiye da sabo-sabo kwayoyi ne SSRI da SIOZSiN. Saboda haka, don magana game da high samuwan tasiri antidepressant magunguna ga masu rinjaye na yawan ba dole. Duk da haka, likita zai iya taimaka a zabi maras tsada miyagun ƙwayoyi da irin wannan Properties, da ake kira Generic.

Hulda da sauran kwayoyi

Antidepressants iya hulɗa tare da wasu kwayoyi, har ma da wadanda wanda ze mana zama lafiya da kuma saba. A mafi yawan aiki a cikin wannan girmamawa ne timoanaleptiki tricyclic da monoamine oxidase hanawa, amma shirye-shirye kungiyoyin SSRIs da SIOZSiN wuya hulɗa tare da wasu magunguna. A cikin wani hali, idan likita ya furta ku da wani magunguna ga ciki, tabbatar da gano idan ba za ka iya hada su liyafar tare da yin amfani da wasu magunguna, abin da ake ci kari, kuma ko da teas da kuma na ganye infusions.

Barasa da kuma antidepressants

Kamar yadda m kamar yadda sauti, amma da yawa mutanen da suke bukatar shiga timoleptikov daban-daban dalilai, tambayar yadda sau da yawa shi ne zai yiwu mu hada da hanyar da "intoxicating" abubuwan sha da Allunan daga ciki. Don amsa wannan tambaya ne quite sauki: idan kana so ka yi hadarin da shafi tunanin mutum da kuma ta jiki kiwon lafiya, kuma watakila rayuwa, kokarin da shi! Gaskiyar cewa barasa da kuma anti-depressants da tsanani sakamako a kan ta tsakiya m tsarin da kuma na kwakwalwa, da kuma wannan biyu matsa lamba iya adversely shafi biyu da "Mission Control Center", watau, kwakwalwa da kuma gabobin da kuma tsarin na rahoton da shi. Ko mu hada - yanke shawarar yarda da ku da kuma kawai ku.

maimakon a ƙarshe

Ba lallai ba ne a yi tunani da kuma "wrestle" a kan, antidepressants da mafi alhẽri, kuma mafi tasiri. Idan ka ji cewa a kowace rana ya zama ƙara wuya zuwa rayuwa fiye da baya daya, karfin da bai isa ko da ga mafi sauki da kuma mundane al'amura, shawarci gwani! Your likita zai iya gane asali da yanayin da rubũta da zama dole magani, zabar mafi dace magani a gare ku. Yana iya ba kawai zama anti-depressants. Arsenal na yau magani ne quite m: daban-daban na psychotherapy, motsa jiki da kuma acupuncture, numfashi dabaru da kuma jiki far.