Alli antagonists - m-bakan kwayoyi

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A rayuwa da kwayoyin tsara alli ions wasa a wajen muhimmiyar rawa. The cewa shi ne alli, iya shiga cikin Kwayoyin iya kunna duk zhiznenovazhnye kwayuka matakai a wani kwayoyin, msl, da hira da ATP a cikin sansanin, ko gina jiki phosphorylation tafiyar matakai.

Regulation na alli ions a cikin jiki

Alli ratsa Kwayoyin ta musamman tashoshi, waxanda suke da manyan sunadarai na gina jiki wanda Alhlulbaiti ta hanyar da multilayer membrane na sel. Wadannan "tashoshi", Inter Alia, da takamaiman rabe, wanda aka za'ayi da katin shaida na alli ions, ba tare da skipping tare da wasu barbashi.

A kwarara daga alli ions a wani kwayoyin da aka kayyade ta musamman na ciki dalilai da za su yi kamar yadda neurogenic asalin kuma zama endocrine shiga tsakani kamar acetylcholine ko serotonin.

Kwayoyi da kuma toshe shigar azzakari cikin farji na alli ions cikin Kwayoyin

Nazarin da kwayoyi da za su iya hana alli tashoshi na da nassi ya fara a cikin 60s, kuma har yanzu faruwa. A farkon wannan nazarin sun bude abu fenilakilamina Kalam, wanda a lokacin da aka gabatar don yin amfani da matsayin koronorasshiryayuschih shirye-shirye. Yau bude quite babban yawan irin wannan abubuwa, wanda ake hada a cikin daya kungiyar, wanda ya karbi sunan - alli antagonists.

Amfani da alli antagonists

Alli antagonists yanzu yadu amfani a fannoni daban daban na magani, wannan shi ne saboda da cewa suna quite mai fadi da kewayon mataki. Saboda haka, misali, alli antagonists iya shafar tsokar contractility, atrioventricular madugu kuma sinus kumburi aiki.

A irin wannan sakamako ne aldosterone antagonists cewa toshe mataki saboda da watsin aldosterone tsoka mai amsa sigina, game da shi kara yawan na alli a cikin sel.

A wasu siffofin pathological yanayi, kamar hypoxia ko ischemia, wuce kima alli ions iya bunkasa kwayuka matakai, haka ne kara nama oxygen bukatar, wanda zai iya haifar da daban-daban pathological effects. A wannan yanayin, da alli antagonists da warkewa sakamako, iyakance mataki na alli ions a cikin cell tafiyar matakai.

Alli antagonists domin lura da cututtuka dangantawa da CAS

Its farko amfani da alli tashar blockers samu yau da magani daga zuciya da jijiyoyin jini cututtuka. Kwayoyi na iya shafar watsin da excitability na zuciya, yana da antianginal effects, inganta jijiyoyin zuciya jini ya kwarara da kuma rage jini.

Kwayoyi da shafi cardiac madugu kuma excitability yau amfani da antiarrhythmic kwayoyi, wanda a cikin sa selection na raba pharmacological kungiyar (angianginalnye nufin).

Antagonists muhimmanci shafi platelet tari, rage su coalescence kuma gudanar da disaggregation na platelets. Wadannan kwayoyi suna amfani da su rage jini danko da kuma kara da elasticity na platelets. Don kara da damar da jini anticoagulant iya nema da kuma bitamin K antagonists cewa rushe da kunnawa da prothrombin, tarewa da samuwar fibrin clots.

Da bakan mataki na kwayoyi

Da bakan mataki na alli antagonists ne da gaske bambancin, saboda su yanzu amfani ba kawai ga zalunta da main iri cututtukan zuciya, amma kuma ga lura da migraine, asma, cuta na cerebral wurare dabam dabam. Alli antagonists taka muhimmiyar rawa a lura da tabin hankali cuta, amfani da magani daga epilepsy da dyskinesia a marasa lafiya tare da schizophrenia.