Kwayoyi "Metodzhekt" da "Methotrexate" - abin da ke bambanci?

A wannan labarin, za mu yi la'akari da shirye-shirye "Metodzhekt" da "Methotrexate". Mene ne bambanci tsakanin su? A wannan daga baya.

"Metodzhekt" shi ne wani anticancer wakili, wanda yana da wani alama immunosuppressive sakamako, shi ne a folic acid antagonist. Iya dakatar da salon salula mitosis. Its main aiki kuma abubuwa a matsayin hanawa na dihydrofolate reductase, a key enzyme na wani rage dihydrofolate tetrahydrofolic acid. A kudin da miyagun ƙwayoyi - daga 700 zuwa 1100 rubles.

Mafi shahara analogue "Metodzhekt" shiri ne na kasar Austria "Methotrexate Ebewe".

da kudin Yana da yake a cikin kewayon daga 400 zuwa 1200 rubles.

Abun da ke ciki "Metodzhekta"

Babban aiki sashi daga cikin miyagun ƙwayoyi ne methotrexate disodium. Ƙarin aka gyara: sodium chloride, sodium hydroxide, distilled ruwa.

Yana da tasiri game da kiwo da kuma hanzari girma Kwayoyin. Musamman shi yana nufin epithelial Kwayoyin da m neoplasms.

A m aikace-aikace accumulates a kyallen takarda. Excreted da kodan da bile. Idan ka damuwa koda aiki, tukar tumbi daga jiki slows saukar. Yana iya kuma rage gudu da matalauta hanta aiki.

A abun da ke ciki na "Methotrexate Ebewe"

Kamar yadda wani ɓangare na miyagun ƙwayoyi ne da wannan aiki sashi - methotrexate. Yana yana immunosuppressive, anti-ciwon daji Properties.

Yana yana da kyau bioavailability excreted a cikin fitsari da kuma adadi kaɗan na bile. Yana o ƙarin tara a kyallen takarda a cikin nau'i na metabolites.

Saboda haka, "Metodzhekt" da "Methotrexate" - abin da ke bambanci? Bisa ga abun da ke ciki da kuma aiki ne kusan m.

A wasu lokuta, da sanya "Metodzhekt"?

Drug "Metodzhekt 'a Oncology yana da wuya amfani. An nuna for fata cututtuka da kuma cututtuka na gidajen abinci, kamar:

• Psoriasis, wanda da wuya a yi wa.
• Rheumatoid amosanin gabbai.
• Na yara amosanin gabbai.
• Psoriatic amosanin gabbai.

Jawo immunosuppressive da anti-mai kumburi Properties na magunguna. Wannan ya bayyana da tasiri a cikin wadannan ailments.

Da amfani da "Methotrexate" miyagun ƙwayoyi

M, "Methotrexate" nuna domin lura da ciwon daji:

• m lymphocytic cutar sankarar bargo.
• trophoblastic cuta.
• fata ciwon daji.
• cutar sankarar mahaifa da kuma vulva.
• ciwon daji na esophagus.
• squamous cell sankara na kai da wuya;
• ciwon daji na koda kafafuwa da kuma ureter.
• kuma osteogenic sarcomas myagkokletochnoy.
• Ewing ta sarcoma, huhu ciwon daji, nono.
• jam cell marurai na testis da kwai;
• hanta ciwon daji, koda ciwon daji.
• retinoblastoma, medulloblastoma.
• penile ciwon daji.
• Hodgkin ta cutar.

Bugu da ƙari kuma, ya kamata a lura da cewa medicament ne amfani da a tsanani siffofin psoriasis kazalika idan akwai mai tsanani rheumatoid amosanin gabbai (idan isasshen far ya m).

Wannan bambanci. "Metodzhekt" da "Methotrexate" ana amfani da daban-daban cututtuka. Saboda haka, "Metodzhekt" - domin lura da psoriasis da amosanin gabbai, kamar yadda "MTX" - a Oncology. Amma su za a iya bi sa'an nan, kuma mafi.

bayar

"Metodzhekt" - wani rawaya bayyana bayani. Sayar tare da syringes, wanda ake nufi da za a gudanar karkashin fata, a cikin tsoka ko jannayẽnsa.

"Methotrexate" ne a ampoules da Allunan.

Kamar yadda amfani da kwayoyi?

A sashi daga cikin miyagun ƙwayoyi zaba ta hanyar halartar likita a kan wani mutum akai. Hakika, idan akwai wani contraindications. Ana amfani ba fiye da sau daya a mako.

A haƙuri dole dauki gwajin kafin amfani. A gaba, a game da wani mako, yin prick gwajin tare da adadi kaɗan na da miyagun ƙwayoyi, idan jiki reacts kullum, lura za a iya za'ayi.

shiri ne da bai sayuwa Lokacin da illa. Da farko, da ƙaramar kashi na medicament aka gabatar, wanda shi ne 7.5 MG. Sa'an nan kuma ya hankali ya karu, tare da mai kyau tolerability kuma data kasance alamomi.

Bayan kamar wata biyu bayan na farko aikace-aikace za ka lura da sakamako. A hanya iya wuce na dogon lokaci, har zuwa shekaru da dama.

A amfani a ciki, kuma lactating mata

Ga bambanci? "Metodzhekt" da "Methotrexate" ba za a dauka a lokacin daukar ciki da kuma lactation.

"Metodzhekt" ne mai guba zuwa tayin iya haifar da tsanani disturbances a cikin ci gaba da kuma har zuwa mutuwarsa. A nono madara o ƙarin tara, wanda kuma iya adversely shafi baby ta kiwon lafiya.

Idan ciki a lokacin jiyya, akwai iya zama a ke so aqibar yaro. Saboda haka yana bukatar mai da hankali maganin hana haihuwa a lokacin far.

Mu kwatanta "Metodzhekt" kwayoyi da kuma "Methotrexate Ebewe". Mene ne bambanci, shi ya m. An bincika kara.

"Metodzhekta" Contraindications

A magani ya kamata ba a yi amfani idan akwai wani hypersensitivity da aka gyara. Kuma ba ya kamata shi a yi amfani a lokacin da:

• Barasa zagi.
• Hanta da kuma kodan.
• Hemodyscrasia.
• Gaban ulcers a cikin narkewa kamar fili da kuma a cikin baka rami.
• Lamba (saboda rage daga cikin rigakafi martani, alurar riga kafi kamata a da za'ayi kawai watanni shida bayan katse liyafar).
• M kuma na kullum cututtuka (ciki har da 'yan cututtuka).
• Autoimmune cututtuka.

Hankali aikace-aikace kasance idan akwai:

• Herpes.
• Pleural da peritoneal effusions.
• Ascites.
• Gout.
• Obstructive cututtuka na narkewa kamar tsarin.
• Dehydration (gaji da damuwa da ruwa balance yana nufin ƙaruwa yawan guba).
• Asthenia.
• A manyan taro na bilirubin.
• Amai da gudawa.
• Gudanar da sinadaran da kuma radiation far tarihi.

"Metodzhekt" kokarin ba su sa tsofaffi, saboda su iya sun lalace hanta da kuma kodan. A musamman, kada amfani da "Metodzhekt" da "MTX" a UC (ulcerative colitis).

A wasu lokuta, an haramta yin amfani da magani, "Methotrexate"?

Lokacin da ya bayyana adam hanta da kuma / ko koda cuta, leukopenia, thrombocytopenia, daukar ciki da lactation. Immunodeficiency jihohi ma contraindicated ga yin amfani da "methotrexate".

Lokacin da magani yi wa rheumatoid amosanin gabbai ko psoriasis, da zarar wata daya, ba jini Biochemistry, kamar yadda a awon yanayi wajibi ne a duba kodan da kuma hanta da mita 1-2 sau da watanni biyu.

Lokacin da psoriasis yana bi, da far da aka ci gaba a cikin gida aikace-aikace na da miyagun ƙwayoyi.

Idan ka faru da yawan abin sama, da mãsu haƙuri dole ne a shigar da & Fonte na alli a lokacin farko da hudu.

Hulda da sauran kwayoyi "methotrexate"

"Methotrexate" haramta amfani da wadannan magunguna:

- maras steroidal anti-kumburi kwayoyi.

- penicillin maganin rigakafi.

- sulfonamides.

- valproic acid.

- colestyramine.

- mercaptopurine.

- neomycin.

- paramomitsinom.

- omeprazole.

- retinoids.

- tetracycline.

- cyclosporine.

Waɗannan su ne contraindications "Metodzhekt" magunguna da kuma "Methotrexate". Mene ne bambanci? Reviews bayar da shawarar cewa su aka canjawa wuri daidai da wuya.

Hulda "Metodzhekta" tare da wasu wajen

Lokaci daya liyafar "Metodzhekta" da sauran kwayoyi kaiwa ko dai don ƙara yawan guba, ko don rage da warkewa sakamako. Idan kana so ka hada da wani wajen, shi ne mafi alhẽri a sanar da gwani.

"Metodzhekt" dauka tare da taka tsantsan tare da:

• Hepatotoxic kwayoyi.
• Kwayoyi, azzaluman jini.
• Kwayoyi da shafi bargo.
• Giya.
• Maganin rigakafi.
• NSAIDs da salicylates.

Haramta jerin magunguna ne babban isa. Yana dole ne a tuna da cewa hulda da "Metodzhektom" zai sa sosai nauyi mai guba guba na jiki (mutuwa Ba a cire). Wani lokaci yana iya kai wa ga fata cancers.

Green shayi da kuma kofi ma suna haramta, kazalika da drinks daga purine alkaloids, theophylline da kuma maganin kafeyin. Dalilin da cewa - bad karfinsu da methotrexate. Yana iya muhimmanci jinkirta su kau.

Ya kamata a lura da cewa a lokacin da samun far nuna bitamin gidaje da kuma shirye-shirye dauke da folate, saboda su rage mai guba Properties.

Wanne miyagun ƙwayoyi zuwa zabi - "Metodzhekt" da "Methotrexate"? Wanne ne mafi alhẽri? A wannan daga baya.

illa

Side effects iya zama daban-daban, amma mafi sau da yawa rinjayar gabobin na gastrointestinal fili. Tare da mita da kuma mai tsanani da suka bayyana, dangane da kashi da mutum halaye da kwayoyin.

Bayyana illa ne, yafi:

• Stomatitis.
• Tashin zuciya.
• Mawuyacin.
• Anemia.
• Dermatitis.
• Ciwon kai da kuma dizziness.
• Wuce kima sweating da kuma zazzabi.
• Nasaba da anaphylactic buga.
• Pericarditis.
• Thromboembolism.
• Interstitial ciwon huhu.
• Daban-daban cututtuka.

wani lokacin:

• Amai.
• Alopecia.
• Vasculitis.
• Pharyngitis.
• Paresthesia daga cikin ƙananan wata gabar jiki, yatsunsu da yatsun kafa.

Very rare:

• Convulsions da inna.
• Kayayyakin hanawa.
• Na huhu insufficiency.
• Myalgia.
• Osteoporosis.

Iya ci gaba pancreatitis, ciwon sukari, rashin ƙarfi, rashin haihuwa, da kuma ko zai yiwu fitowan da siffofin maruran.

Mene ne bambanci tsakanin kwayoyi 'Metodzhekt "da" Methotrexate "? Wannan tambaya ne ban sha'awa ga mutane da yawa.

Tabbata a yi yau da kullum Nazarin ga waɗanda marasa lafiya da suke da ake jinyar "Metodzhektom". Kamar haka za a iya hana maye. Tsanani sakamakon wannan mummunan, yiwu m.

Haramta tuki a lokacin far da kuma aiki tare da m kayan.

Next, la'akari da gefen sakamakon kwayoyi kamar "Metodzhekt" da "MTX". Mene ne bambanci tsakanin su?

Side effects "methotrexate"

A kan wani ɓangare na narkewa kamar tsarin iya zama manifestations ulcerative stomatitis, anorexia, gingivitis, pharyngitis, tashin zuciya. a rare lokuta - zawo, melena, enteritis, pancreatitis, hanta necrosis, cirrhosis, mai atrophy, periportal fibrosis.

hematopoietic tsarin iya amsa leukopenia, anemia, thrombocytopenia.

Jamhuriyar juyayi tsarin - gajiya, dizziness. a rare lokuta - da ciwon kai, aphasia, sleepiness, convulsions.

Haihuwa tsarin - wani take hakkin oogenesis da spermatogenesis, oligospermia, hailar magudi, rage libido, rashin ƙarfi.

Urinary tsarin - hematuria, cystitis, mai tsanani mai illa na koda aiki.

Iya tabbatar da wadannan rashin lafiyan halayen: zazzabi, rage juriya to kamuwa da cuta. a rare lokuta - urticaria, mai guba epidermal necrolysis, Stevens-Johnson ciwo.

Dermatological halayen - fata rash, photosensitivity, pigmentation cuta, kuraje, tafasa.

Lokacin da wani m halayen da miyagun ƙwayoyi kamata nan da nan a tuntuɓi likita.

yawan abin sama

An yawan abin sama ne m ga hematopoietic tsarin. A cikin wadannan lokuta, da kwayoyin ne a hydration. Wannan zai iya bugun sama da excretion na aiki abu. Har ila yau sanya sami folic acid.

Yanayi da kuma sharuddan

Mun la'akari "Metodzhekt" da "Methotrexate". Bambanci a shiryayye rai ne kuma samuwa.

A bushe, duhu wuri a zazzabi ba wucewa 25 digiri, ci gaba da wadannan magunguna. Tabbata a tsabtace daga yara. Hasken rana da kuma danshi suna contraindicated. Daskare su ba zai yiwu ba.

"Metodzhekt" m for 2 shekaru daga ranar yi, "Methotrexate" - 3 years.

Wadannan daban-daban "Metodzhekt" da "Methotrexate". Mene ne bambanci tukuna?

A kwatanta da "Metodzhektom", za ka iya zaɓar wasu daga cikin fitattun ingancin "methotrexate". Side effects ne zai yiwu, amma, a cikin ra'ayi na marasa lafiya, zamanto kasa akai-akai. "Methotrexate" shi ne kuma samuwa a cikin alluna, domin da yawa marasa lafiya, wannan nau'i ne mafi m.

Saboda haka, mun bayyana a cikin daki-daki, ga yin amfani da "Metodzhekt" kwayoyi da kuma "Methotrexate". Mene ne bambanci, shi ne a yanzu bayyananne.