"Cymbalta": umarnin don amfani. Reviews, farashin, alamomi

A yau zamu gaya maka game da shirin na "Simbalta" shine. Umurnai don yin amfani da wannan magani, da abun da ke ciki, abubuwan lalacewa da alamomi zasu bayyana a ƙasa. Har ila yau daga labarin da aka gabatar za ku koyi game da hanyar da aka bayar da wannan magani, koda halin da ake ciki, ko yana da takaddama da yadda za a yi amfani da shi daidai.

Nau'in batun

A wace hanya zan iya saya shirye-shirye na "Simbalta", wacce takarda ta haɗa a cikin marufi? A halin yanzu, wannan magani yana samuwa ne kawai a cikin nau'i na sutura mai sutura. Kuma kowanne daga cikinsu yana dauke da pellets, wanda suke da launin fari ko launin fari-launin fata.

Tsarin shiri

Wadanne abubuwa ne abin da ke cikin magani na Simbalta ya ƙunshi? Umurnin yin amfani da capsules sun furta cewa babban mahimman aiki shine duloxetine. Ya kamata kuma a lura da cewa, tsarin da la'akari medicament da ya hada da ƙarin abubuwa kamar sucrose, hypromellose, talc, succinate, fari colorant, hypromellose acetate, titanium dioxide, triethyl citrate, gelatin, sodium lauryl sulfate da kuma rawaya baƙin ƙarfe oxide pigment.

Capsules zasu iya ƙunsar 60 da 30 MG na miyagun ƙwayoyi. An kwashe su a cikin blisters don 14 ko 7 capsules. A cikin kwandon katako akwai iya zama 1, 2 ko 6 blisters.

Harkokin Pharmacological na miyagun ƙwayoyi

Menene abu mai aiki kamar duloxetine? Umurnai na yin amfani da magani capsules ya furta cewa, irin wannan magani addashin da ya ce kashi ne sosai kyau antidepressant. Yana da mai hana reuptake na norepinephrine da serotonin. Yana dan kadan ya hana kama dopamine, kuma ba shi da dangantaka da dopamine, histamine, cholino- da adrenoreceptors.

Ta yaya aikin duloxetine ke aiki? Umurnin yana dauke da bayanan da ke cikin wannan asusun: ka'idar aiki ta wannan abu shine don kawar da norepinephrine da serotonin. A sakamakon haka, ƙananan ƙwayoyin neradrenergic da serotonergic a cikin mummunan tsarin ya kara karuwa. Ya kamata a lura cewa duloxetine da sauri ya kawar da ciwon ciwo.

Pharmacokinetics na miyagun ƙwayoyi

Magunguna daga ciki kamar "Simbalta" suna shayewa daga fili mai narkewa, tsotsa farawa kamar 'yan sa'o'i kadan bayan rikici. Yawancin adadin ya isa bayan sa'o'i 6. Abincin abinci guda daya ba zai tasiri maida hankali ba, amma yana ƙaruwa lokacin da yake ɗauka daga 6 zuwa 10 hours. Masana sun ce wannan kai tsaye ya rage digirin sha (ta 11%).

Rage da miyagun ƙwayoyi zuwa sunadaran plasma yana da cikakkiyar isa kuma ya kai fiye da 90%.

Rabin rabi na miyagun ƙwayoyi yana da sa'o'i 12. A lokaci guda ya tafi tare da fitsari a cikin nau'i na metabolites.

Bisa ga binciken, akwai bambance-bambance a tsakanin tsarin aiwatar da kwayoyin pharmacokinetic dake faruwa a mata da maza. Sabili da haka, rashin daidaituwa ga bangaren aiki yana da ƙananan cikin jima'i. Duk da haka, babu buƙatar daidaita tsarin.

Ya kamata a lura cewa a lokacin nazarin, an kafa bambance-bambance a tsakanin tsarin maganin pharmacokinetic wanda ya faru a tsofaffi da marasa lafiya. An gano cewa rabin rayuwar miyagun ƙwayoyi ya fi girma a cikin tsofaffi fiye da matasa. Ba'a buƙatar gyaran gyare-gyaren gyare-gyare.

A marasa lafiya da na kullum koda insufficiency a m mataki, wanda suke a dialysis, da maida hankali cika shiyya da sauran na duloxetine ƙaruwa a daidai sau 2. Wannan shine dalilin da ya sa aka ba da shawarar yin la'akari da yadda za a rage saurin maganin miyagun ƙwayoyi a marasa lafiya tare da ciwon ƙwayar cuta mai tsanani.

A cikin marasa lafiya tare da alamun cututtukan hanta, ana iya rage jinkirin rayuwa da rabi na duloxetine.

Indiya don amfani

Yaushe ne kalmar "Simbalta" ta wajabta? Umurnin don amfani ya hada da jerin abubuwan da ke nunawa:

• Ciwon ƙwayar cutar ciwon sukari na wata hanya mai raɗaɗi;
• Matsanancin ciki da rashin tausayi;
• Cutar rashin tausayi da yawa;
• Ciwo na ciwo na zamani na tsarin musculoskeletal, ciki har da wadanda fibromyalgia da osteoarthrosis suka haifar.

Contraindications ga amfani da samfur

Lokacin da ba za ka iya daukar maganin "Simbalta" ba? Umurnai don amfani sun hada da jerin biyun na contraindications:

• Ɗaya daga cikin aikace-aikace na masu hana masu karfi na isoenzyme CYP1A2 (misali, enoxacin, ciprofloxacin ko fluvoxamine);
• Ƙara yawan haske ga mai haƙuri zuwa ga wakilan wakili;
• Yara a karkashin 18;
• Gudanar da gwamnati tare da masu zanga-zangar MAO;
• Jijiya hauhawar jini ne uncontrolled.
• Glaucoma an rufe-kwana ba tare da komai ba;
• CRF mai tsanani (tare da QC kasa da 30 ml / min);
• Raunin isomaltase ko sucrose, glucose-galactose malabsorption da rashin haƙuri ga fructose;
• Cutar cutar, wadda ke tare da rashin hanta.

Lokacin amfani da kula da maganin

Yana da kyau sosai don amfani da miyagun ƙwayoyi a cikin cututtuka da kuma mania, damuwa, hadarin harin da aka rufe-angle glaucoma. Har ila yau, dole ne a dauki kulawa tare da hauhawar jini na intraocular, tunanin suicidal, hyponatremia, hanta hanta da koda.

Shirye-shirye na "Simbalta": umarnin don amfani

Farashin wannan magani yana da yawa. Duk da haka, tasirinsa ba shi da wata shakka.

Magungunan da aka gabatar da shi an umarce su ne kawai don gudanar da maganganun jiha. Dole ne a yi amfani da matsurar ruwa gaba daya, ba tare da kintsawa ba. Ya kamata a lura da shi sosai cewa ba za ku ƙara miyagun ƙwayoyi zuwa abinci ba ko haɗuwa da shi tare da kowane taya, tun da irin wannan aikin zai iya lalata alamar shiga ciki.

Drugs for depression ya kamata a dauka a wani farko asali daidai 60 mg sau ɗaya a rana. Don samun sakamako mai kyau, wasu marasa lafiya sun ƙara wannan ƙarar zuwa kashi 120 na sau biyu a kowace rana.

A cikin marasa lafiya wanda aka gano tare da ciwon kodayake na kodayake, wanda ke faruwa a cikin matsakaici, matakin farko na miyagun ƙwayoyi ya zama 30 MG sau ɗaya a rana. Idan marasa lafiya suna fama da cutar hanta, to, an nuna yawan yawan miyagun ƙwayoyi don ragewa ko rage yawancin gwamnatin.

Ya kamata a lura cewa yana da muhimmanci don kauce wa cirewa mai magungunan magani. Yawan adadin miyagun ƙwayoyi ya kamata a rage shi da hankali a cikin makonni 1-2. Idan akwai alamomi na karba a kan wannan batu, to ana bada shawara don ci gaba da kulawa a takardun tsari. Daga bisani, likita na iya ci gaba da rage layin, amma har ma da sannu a hankali.

Cases na kariya

Mene ne masana suka ce game da sha'anin overdoses da miyagun ƙwayoyi "Simbalta"? Binciken likitoci sun ƙunshi bayanin da suke da irin waɗannan bayanai. Har zuwa yau, akwai lokuttan overdose lokacin shan miyagun ƙwayoyi a cikin adadin har zuwa 3000 MG, da haɗin tare da wasu hanyoyi. By hanyar, daya mutuwa da aka rubuta.

Alamomin hadewa ko rarraba overdose su ne yanayin da ke biyowa: clonic convulsions, drowsiness, vomiting, coma, tachycardia da serotonin ciwo. Dangane da ƙaddamarwar binciken (gwaje-gwajen dabba), ainihin bayyanar cututtuka da ke hade da amfani da maganin shan magani ba tare da amfani ba ne na rashin lafiya da tsarin narkewa. Har ila yau, marasa lafiya na iya shawo kan rawar jiki, ataxia, clonic convulsions, vomiting da asarar ci.

Menene za a yi idan akwai wani kariya? Tare da ci gaban serotonin ciwo ya kamata a nan da nan da za'ayi daidaituwa far cyproheptadine, kazalika da hanyoyin amfani da su normalize haƙuri da yanayin jiki.

Mai haƙuri yana buƙatar samar da iska mai tsabta. Har ila yau ya kamata ya kula da aikin zuciyarsa da kuma kula da rayuwa. Duk wannan dole ne a yi tare tare da goyon baya da jiyya alama.

Idan baku da isasshen lokaci tun lokacin shan magani, ya kamata ku wanke ciki. Har ila yau, domin ƙayyadadden shayar da magani, an karfafa mai haƙuri ya sha abincin da aka kunna.

Hanyar gefe

Za a iya samun lafiyar mutum ta hanyar karɓar magani? Ka yi la'akari da illar da kwayoyin antidepressant suka haifar da karin bayani:

• Sau da yawa sosai (a 10% na lokuta) a cikin asibiti karatu, marasa lafiya da wadannan jihohi: dizziness, ciwon kai, bushe baki, rashin barci, rashin barci, tashin zuciya, drowsiness da maƙarƙashiya.
• Mafi yawancin (daga 1 zuwa 10% na lokuta) a cikin marasa lafiya sunyi haske, zazzabi, hangen nesa, vomiting, sweating, raguwa, ƙarar daɗaɗɗa, rage yawan ci abinci, rage libido, asarar nauyi, rauni, cin hanci da rashawa, da jinkirta ko halayen haɗari.

Mutum ba zai iya taimakawa ya ce irin wannan tasiri ba, kamar lazuka (wani lokacin ciwon kai da kuma tashin hankali), ana lura da shi lokacin da aka kawar da miyagun ƙwayoyi. A hanyar, a cikin marasa lafiya da marasa lafiya na ciwon sukari na wata hanya mai raɗaɗi, za a iya kara karuwa a glucose mai azumi mai azumi.

Bayani game da miyagun ƙwayoyi

Bisa ga nazarin masana kimiyya da marasa lafiya, likitancin da aka yi la'akari da shi ya dace da aikin. Bayan daukan shi, zai kawar da rikice-rikice, kuma yana inganta kwata-kwata daga jihar. Bugu da ƙari, wannan magani yana kawar da ciwo na ciwo a cikin tsarin ƙwayoyin cuta.

Haɗi tare da wasu hanyoyi

Shin zai yiwu a gudanar da haɗin gwiwa tare da wasu kwayoyi tare da maganin "Simbalta"? Masana sun ce wannan maganin ya shafi tasirin wasu magunguna.

Saboda haka, akwai hadarin bunkasa ciwon serotonin idan an yi amfani da duloxetine tare da MAOI.

Dangane da gaskiyar cewa CYP1A2 isoenzyme ke taka rawar gani a cikin ƙaddarar shirin Simbalta, yin amfani da su guda daya zai haifar da karuwa a cikin maida hankali na karshen.

Ba'a ba da shawarar yin rubutun wannan magani tare da wasu magunguna da suka shafi tsarin kulawa na tsakiya. Har ila yau, a lokacin karbar ta ba za ta sha barasa ba.

Wani lokaci tare da yin amfani da kwayoyin SSRI da kuma kwayoyin sutura a cikin marasa lafiya akwai ciwon serotonin. Saboda haka, ya kamata a dauki kulawa mai kyau lokacin amfani da wannan miyagun ƙwayoyi tare da magungunan antioxpress.

Dangane da gaskiyar cewa akwai yiwuwar haɗarin jini, kada ku yi amfani da duloxetine da anticoagulants (antithrombotic kwayoyi) lokaci guda.

Yarayar ciki da ciki

Zan iya yin amfani da miyagun ƙwayoyi "Simbalta", wanda farashin za a gabatar a baya, a yayin daukar ciki? Saboda rashin cikakken bayani game da yin amfani da duloxetine a lokacin lokacin gestation, wannan magani zai iya ba da izini ne kawai idan amfana ga mahaifiyar da ke da tsammanin tana da muhimmanci fiye da hadarin jariri.

Ya kamata a lura cewa marasa lafiya suna daukar wannan magani ya kamata su gargadi likita game da farawa ko kuma shirin daukar ciki.

Nazarin ya nuna cewa shan maganin antidepressants a cikin mata, musamman ma a lokuta na baya, yana ƙara haɓakar cutar hawan jini a cikin jaririn jarirai. Bugu da ƙari, an kawar da ciwo daga ƙwayar cuta a yara a yayin da aka yi amfani da duloxetine mai mahimmanci daga mai yiwuwa uwa ta kasance cikin ciki. Yawancin alamun bayyanar wannan yanayin an kiyaye a lokacin haihuwa ko kuma a cikin kwanakin farko.

Saboda gaskiyar cewa duloxetine zai iya shiga cikin madarar mahaifiyarsa, yana da wanda ba a so a ciyar da jaririn a lokacin farfadowa. In ba haka ba, ƙaddamar da wannan abu a cikin tayin zai kasance cikin adadin 0.14% na maida hankali cikin mahaifi.

Musamman jagorancin amfani da miyagun ƙwayoyi

Bayan da ya sanya magungunansa magani "Simbalta", likita ya wajaba ya sanar da shi cewa an haramta shi sosai don daukar wannan maganin nan da nan tare da magoya bayan MAO. In ba haka ba, zai iya zama m, da kuma matsaloli mai tsanani a cikin hanyar hyperthermia, myoclonus kuma furta tashin hankali tare da miƙa mulki zuwa coma.

Ya kamata kuma a lura da cewa, an hana sami ce magani ga makonni biyu bayan lura Mao hanawa.

Bisa ga binciken, a cikin marasa lafiya tare da yanayin manji tare da yin amfani da wasu magunguna da suka shafi tsarin jin tsoro, tare da "Simbalt" na nufin, cutar ta yanzu za ta iya kara.

Bisa ga gaskiyar cewa akwai yiwuwar yunkurin kashe kansa a cikin jihohi masu ciwo, musamman ma marasa lafiya a hadarin ya kamata a kiyaye su.

Yin shan wannan magani zai iya haifar da lalata. A wannan yanayin, marasa lafiya da suke shan wannan magani, ya kamata ku karbi karin kulawa lokacin yin tuƙi da inji yayin da kuke aiki tare da hanyoyin haɗari masu haɗari.

Farashin da analogues na maganin magani

Nawa ne magungunan na intestinal na Simbalt? Farashin su na iya zama daban. Ya dogara ne da masu sana'a da alamar kaya na kantin magani. Duk da haka, ya kamata a lura cewa a matsakaicin wannan miyagun ƙwayoyi yana kimanin kimanin 1050 Rasha rubles (30 MG, 14 guda). Idan kana buƙatar sayan magani a cikin irin wannan adadin, amma a sashi na 60 MG, to, dole ne ka ba da kimanin 1150 rubles.

Yanzu ku san kimar farashin duloxetine. Farashin shi zai iya ƙara ko rage dangane da wasu dalilai. A halin yanzu, sayan wannan magani bai da wuya. Duk da haka, zaka iya saya shi ta hanyar takardar sayan magani.

Amma idan kayi wani dalili ba zai iya sayan maganin magani na Simbalt ba? Analogs na wannan magani suna samuwa a kusan dukkanin kantin magani. Ko da yake sayen su zai buƙaci takardar sayan magani daga likita.

Me zai iya maye gurbin magani Simbalta? Daga cikin takwarorinsa, Ina so in jaddada wa annan maganin:

• "Intrusion";
• "Azafen" (Allunan);
• "Duloxetine canon" (shigarwa capsules);
• "Venlafaxine Sandoz";
• "Alventa";
• "Canon Mirtazapin";
• "Bethol" (bayani ga gwamnatin iv da / m);
• "Wellbutrin";
• "Bethol" a cikin Allunan;
• "Waldoxan";
• "Neuroplant";
• Velafax;
• "Kaliksta";
• "Venlaksor";
• Venzuert;
• "Dapfix";
• "Harkokin Odin".
• "Tsarin";
• "Efewelon jinkirta";
• "Doppelherz Nervotonik" a cikin wani elixir;
• "Inkazan";
• "Ephevelone";
• "Coaxil";
• "Ruhu";
• "Lerivon";
• Trittico;
• Normazidol;
• Mirzaten;
• "Tetrindol";
• Mirtazonal;
• "Ka tuna";
• Mirtalan;
• "Pyrazidol";
• "Negrustin";
• Newvelong;
• "Noxibel."

Hanyar ajiya da rayuwa mai shiryayye

Mene ne shiryayye rayuwa da miyagun ƙwayoyi "Cymbalta?" Bisa ga umarnin, da kuma kwanan wata a kan marufi, wannan kayan aiki da ba za a dauka na tsawon shekaru uku. A wannan yanayin ya kamata a adana a cikin duhu wuri inda zafin jiki ba ya wuce 20 digiri.