A aikace-aikace da kuma sakamako na "Cefotaxime." "Cefotaxime": wani analogue da miyagun ƙwayoyi

Kwayoyin "cefotaxime" - wani iko da miyagun ƙwayoyi domin lura da cututtuka da kuma rigakafin postoperative rikitarwa. Da miyagun ƙwayoyi gabatar a cikin jiki ta hanyar allura, shi ne sau da yawa wajabta duka biyu manya da yara. Yana da wani semisynthetic kwayoyin da aiki abu sefotaksim sodium.

pharmacological effects

"Cefotaxime" - Wakilin cephalosporins, bactericidal mataki ne tabbatar da danniya na samuwar cell ganuwar da kwayoyin cuta.

Antimicrobial ne aka yi nufi ga parenteral amfani, shi ne tasiri lokacin da fallasa su gram-korau kwayoyin da suke resistant zuwa wasu maganin rigakafi, iya aiki a kan gram-tabbatacce cocci, amma kasa aiki fiye da gram-korau kwayoyin.

Pharmacokinetics

Da miyagun ƙwayoyi ne hanzari tunawa, dangane da sashi ne a cikin jini na minti biyar ko rabin awa bayan alura da kuma kula da bactericidal yawa a cikin jini don fiye da 12 hours. Da miyagun ƙwayoyi ne shigar da nama da kuma m, da rarraba a gare su. Lokacin amfani da lactation magani iya samun cikin nono. Matsakaicin sakamako "Cefotaxime" da aka cimma a lokacin da tasiri yawa a cikin synovial, peritoneal da pleural ruwaye. Derivation aka yi canzawa a fitsari (game da 60%) kuma a cikin nau'i na metabolites. Domin rabin-rai a sakamakon V / m da / a bukata 1 hr.

Alamomi ga yin amfani da medicament

Alamomi ga yin amfani da kwayoyi ne dauke da kwayar cutar yanayi na kumburi tsokane ta micro-kwayoyin da suke da daban-daban sensitivities zuwa "cefotaxime" (yafi gram-korau). Bayar kawai yana nufin for injections "Cefotaxime" analogs a Allunan samuwa, da miyagun ƙwayoyi ne a yi amfani da gano irin jihohi:

• kamuwa da cuta ta shafi kogon ciki.
• raunuka na fata, da gidajen abinci, taushi da nama da kashi;
• cututtuka na numfashi fili, hanci, makogwaro, kunnuwa.
• kamuwa da cuta ta shafi cikin urinary tsarin.
• Lyme cuta.
• kumburi tafiyar matakai na dauke da kwayar cutar halitta a cikin pelvic gabobin, kabba da ciwon sanyi.
• konewa, kamu raunuka.
• meningitis, endocarditis, septicemia.
• cututtuka na immunocompromised.
• rigakafin cutar bayan m hanyoyin (ayyukan a kan gastrointestinal fili gabobin, obstetric kuma gynecological da kuma urological hanyoyin).

contraindications

"Cefotaxime" analogues a injections da wasu contraindications cewa dole ne a yi la'akari kafin gwamnati da miyagun ƙwayoyi.

Da miyagun ƙwayoyi ne contraindicated a hali na hypersensitivity zuwa penicillins, carbapenems da sauran cephalosporins. Its a hankali wajabta hanta da koda cututtuka, ulcerative colitis, lactation. Mata masu ciki da ke wajabta kawai idan akwai wani babban hadarin da tayin ko uwar jiki ya kamata su amfana muhimmanci outweigh da yiwu kasada. Lokacin amfani dangane da yara a ƙarƙashin da shekaru 2.5 years, ba a yarda a yi amfani da da hanyar da intramuscular allura.

Amfani da miyagun ƙwayoyi, sashi

Don san yadda za a yi kiwo "cefotaxime", shi wajibi ne don karanta bayanai ba a cikin umarnin don yin amfani da miyagun ƙwayoyi. Magani yi nufi ga wani / m da / a cikin gabatarwar (via wani dropper ko bolus).

Da miyagun ƙwayoyi An wajabta ga marasa lafiya girmi shekaru 12, lokacin da jiki nauyi ne mafi girma daga 50 kilo:

• cututtuka na urinary fili a kuma waɗannan lokuta idan da kamuwa da cuta auku ba tare da rikitarwa kwayoyin da wani Hanyar samuwa samar 1 g na cikin shirye-shiryen da jinkiri na 8-12 hours;
• uncomplicated m kabba da ciwon sanyi siffofin gudanar singly da intramuscular hanya 1 g na miyagun ƙwayoyi.
• yin amfani da wani magani domin lura da cututtuka na dauke da kwayar cutar yanayi, mai tsanani daga wanda yake matsakaici, da wani daga cikin hanyoyin da 1-2g aka gudanar da wani periodicity nufin 12 hours (kafin shuka "Cefotaxime", shi wajibi ne don ci gaba da binciken dokokin bisa ga abin da mafita aka shirya domin allura) ;
• tukuru faruwa cututtuka, msl, meningitis, bukatar da gabatarwar a cikin jijiya 2 g da miyagun ƙwayoyi a kan jinkiri na 4-8 hours, tare da matsakaicin kashi da rana na iya zama ba fiye da 12 g; duration magani ne m da tsanani daga cikin yanayin.
• kafin gudanar a lokacin maganin sa barci da ya kawar da alama na kamuwa da cuta ne gudanar 1 g da miyagun ƙwayoyi, a wasu lokuta 6-12 hours aka kwashe reintroduction nufin;
• cesarean sashe da aka yi da gabatar da 1 g of "Cefotaxime" daga baya da hanya da aka maimaita.

Da miyagun ƙwayoyi ana amfani intravenously dangane da wanda bai kai ba jariran da jarirai:

• shekaru ne kasa da sati 1 - yi amfani da 50 MG da 1 kg na jiki nauyi da mita 12 hours.
• shekaru 1 zuwa 4 makonni - 50 MG da 1 kg na jiki nauyi da periodicity na 8 hours.

Yara da suke auna kasa da 50 kilo yana da shekaru 2.5 years, sanya 4-6 Gabatarwa Daya daga cikin yiwu hanyoyin da 50-180 MG da kilogram na jiki nauyi (za a fahimci matsayin "cefotaxime" irin novocaine, ya kamata ka karanta umarnin a hankali) . Idan akwai mai tsanani Hakika na cuta, da yin amfani da 100-200 MG / kg. A ranar ne m zuwa 12 g da miyagun ƙwayoyi.

Shiri na mafita ga allura

igiyar jini allura

A bakararre ruwa ga allura (4 ml) da aka diluted da 1 g daga cikin miyagun ƙwayoyi. The bayani ne gudanar kan 3-5 minti, yana da muhimmanci ga samar da wani jinkirin isar a cikin jiki.

Igiyar jini jiko (drip)

A 50-100 ml na sauran ƙarfi (dextrose 5% ko sodium chloride 0.9% th) diluted 1-2 g na miyagun ƙwayoyi da kuma jiko ne da za'ayi domin 50-60 minti.

intramuscular

A 4 ml na bayani (1% novocaine bayani -th, ruwa ga allura) dauki 1 g da miyagun ƙwayoyi, sa injections a gindi, da allura dole shiga zurfi cikin tsoka.

Yarda da magani umarnin yin amfani da

"Cefotaxime" analogues a Allunan for wanda akwai samuwa, amfani a yarda da takamaiman umarnin. Kafin da ake ji da magani dole don ware da alama na allergies. Marasa lafiya da suke iya zama wani rashin lafiyan dauki penicillin, da miyagun ƙwayoyi ya kamata a yi amfani da tare da matsananci hankali. Idan akwai ƙwarai zuwa ga abubuwa dauke a cikin magani samfurin, ta yin amfani da aka tsaya. A lura da fiye da kwanaki 10 na bukatar lokaci-lokaci dubawa na gefe jini wurare dabam dabam. Don kawar a ke so halayen a lokacin jiyya da bukatar daina barasa.

Overdosing illa

"Cefotaxime" analogues a dakatar da manyan yawan illa:

• rashin lafiyan halayen (urticaria, itching, rash, zazzabi, jin sanyi, bronchospasm, anafillaksiya, eosinophilia, angioedema, mai guba epidermal necrolysis da Stevens-Johnson).
• dyspepsia (zafi a ciki, dysbacteriosis, flatulence, tashin zuciya da amai, maƙarƙashiya ko zawo, cuta na hanta, a rare lokuta - pseudomembranous colitis).
• glossitis, stomatitis.
• disturbances a hematopoiesis tsarin (hypocoagulation, hemolytic anemia, thrombocytopenia, granulocytopenia, neutropenia, leukopenia).
• munanan a cikin urinary gabobin (interstitial nephritis, anuria, oliguria, azotemia, high matakan da urea a cikin jini).
• dizziness, ciwon kai.
• korau matakai a cikin zuciya da jijiyoyin jini tsarin (arrhythmias ɗauke da m barazana ga rayuwa).
• a ke so gida halayen (infiltrate, m / m, phlebitis).
• canje-canje a cikin dakin gwaje-gwaje sigogi (ƙarya m Coombs 'test).
• superinfection (baka candidiasis, Candida vaginitis).

"Cefotaxime" analogue da miyagun ƙwayoyi a lokacin da amfani da, a high allurai zai iya kai ga yawan abin sama, ya bi ta hanyar convulsions da kuma sauran cututtuka, daga gare su - da tashin hankali, tremors, encephalopathy (sau da yawa sosai da wannan alama da aka lura a marasa lafiya fama da koda gazawar). Don kawar da sakamakon wani yawan abin sama symptomatic magani da ake amfani.

Drug hulda da sauran magunguna

Idan kana bukatar ka sãmi tare da wani abun da ke ciki kama da abun da ke ciki na kudi "cefotaxime" analogue tara ba zai zama da wuya. Amma babu matsala, tare da taimakon miyagun ƙwayoyi far aka yi amfani da asali analogue ko, a wani hali, kana bukatar ka yi la'akari da hulda da miyagun ƙwayoyi da sauran magunguna.

Lokacin da "cefotaxime" ta shafi biyu, zuwa yiwuwar nephrotoxic kwayoyi kamar furosemide, aminoglycoside maganin rigakafi, yana da muhimmanci mu tsayar da aikin da kodan, saboda hadarin nephrotic tasiri.

Domin lura da yawa cututtuka da kuma hana su ci gaba da sau da yawa suna amfani da "cefotaxime". Umurnai na amfani, da miyagun ƙwayoyi analogues sun da za a yi karatu, kamar yadda da wannan kayan aiki na iya haifar da allergies, yana mai yawa illa da sauran fasali. A mafita daga cikin miyagun ƙwayoyi ba a yi amfani a tare da sauran mafita na maganin rigakafi, su ba za a iya haɗa ta drip jam'iyya da kuma sirinji.

analogs

Yana nufin for "cefotaxime" analog dole ne a zaba domin aiki abu. Tsarin analogues za a iya gano:

• cefotaxime sodium.
• cefotaxime vial, Sandoz, sodium da kuma lek.
• tsefosin.
• tsefantral.
• tsefabol.
• tsetaks.
• tirotaks.
• tartsefoksim.
• taltsef.
• haraji-to-karo.
• spirozin.
• rezibelakta.
• oritaksim.
• oritaks.
• liforan.
• klafotaksim.
• klaforan.
• klafobrin.
• kefoteks.
• intrataksim.

Tun da akwai wani m kewayon kayayyakin aiki, don shirye-shiryen "cefotaxime" analog zabi sauki, amma t. Don. A analogs iya samun wasu sakamako masu illa, da waraka sakamako iya zama weaker, ya maye gurbin asalin miyagun ƙwayoyi ya kamata a zaba sosai a hankali. Don kauce wa a ke so sakamakon, kamata koyi a matsayin mai yawa bayanai game da kwayoyi da aka shirya za a yi amfani da.