Umurnai "Gonal-F." Description of shiri, contraindications, analogs da kuma sake dubawa

Daya daga cikin na kowa hanyoyin da rashin haihuwa da magani ne ta tuntubo ovulation. Domin mahara qwai dace hadi, shi wajibi ne don gudanar da wani musamman pre-miyagun ƙwayoyi far. "Gonal-F" da aka dauki daya daga cikin mafi inganci da kwayoyi a cikin wannan yanki. Umurnai "Gonal-F" karfi da ya bada shawarar magani a karkashin tsauraran likita dubawa.

description of

Kowa ya san cewa ba tare da ovulation ciki ba zai iya faruwa. Saboda haka, da yawa daga cikin adalci jima'i, da fuskantar irin wannan matsalar da za a warware su kara kuzari da kuma a vitro hadi. A halartar likita dole ne farko gudanar da wani likita jarrabawa, karba daidai makirci na da hanya da kuma dace shirye-shirye.

A mafi aminci da tasiri kayan aikin ne bisa follicle stimulating hormone - FSH (recombinant), wanda shi ne ke da alhakin maturation na follicles a mata. Umurnai "Gonal-F" rahoton cewa da miyagun ƙwayoyi nasa ne wannan category, da kuma ginshikai na mataki ne a matsayin kusa da na halitta FSH. Saya magani kawai a kan ganin likita.

alamomi

Drug bukatar a gynecological filin da aka sanya a lokacin da ka kunna ci gaban da follicles. Alamomi ga yin amfani da "Gonal-F" yana da wadannan:

• Rashin ovulation da unsatisfactory sakamakon bayan da ake ji "Clomiphene".
• Polycystic ovarian ciwo (Pathology alaka hormonal cuta haddasa matsalar aiki na samfur na ovaries).
• Da bukatar kara kuzari na mahara follicles for IVF.

Da yawa likita karatu sun tabbatar da inganci na da miyagun ƙwayoyi a lokacin da ya cancanta ci gaban mahara follicles a kan aiwatar da ovarian hyperstimulation (sarrafawa). Yana da aka kafa da cewa aiki sashi na inganta ci gaban da follicles, kuma ta haka ne da yawa rage hadarin na ovarian hyperstimulation.

Aikace-aikace don maza

Lokacin da ba yarda da asali ayyuka na namiji gonads na spermatogenesis tsari - da samuwar da kuma ci gaba na maniyyi - ya karye. Follicle haramta motsa hormone zama dole domin "a fara" na wannan tsari, wanda yana kwanaki 75. Gane pathological jihar mai yiwuwa ne kawai bayan da nassi daga likita bincikowa da kuma isar da maniyyi.

Ruri (ko mayar) da al'ada samuwar ɗa namiji gametes wani lokacin daukan tsawon fiye da wata kama hanya a mata. Ga wani tabbatacce sakamakon magani ya kamata cika cikakken tare da shawarwari andrologist. Dole ne ka bi don wani musamman tsara rage cin abinci, ba da yin amfani da barasa da nicotine. Shi ne m sanya shirye na musamman. Umurnai "Gonal-F" na nuna cewa da miyagun ƙwayoyi za a iya amfani da su inganta spermatogenesis a maza da suke da nakasar ko samu hypogonadism. Far ya zama karkashin m dubawa da wani gwani wanda yana da kwarewa a lura da rashin haihuwa.

da miyagun ƙwayoyi

Active bangaren na miyagun ƙwayoyi abubuwa follitropin Alfa - wani abu da stimulates da girma da follicles a mata da disturbances a cikin hypothalamic-pituitary tsarin. A bioavailability da miyagun ƙwayoyi a lokacin gudanar subcutaneously ya game 70%.

Aiki sashi fara tara a cikin kwayoyin bayan maimaita gwamnati. A lokacin farko 3 days lura duffai uku kara da ma'auni taro na follitropin Alfa, wanda yana farawa ruri tsari.

Karin aka gyara dauke a cikin miyagun ƙwayoyi daga sodium hydroxide da hydrogen phosphate dihydrate, phosphoric acid, methionine, sucrose, polysorbate 20.

saki Form

"Gonal F" samar da wani Italian Pharmaceutical kamfanin "Industry Farmasyutika Serono Spa". Form saki wakili - mafita ga subcutaneous allura da kuma lyophilisates ga ruwa.

A syringes a cikin nau'i na alkalama iya ƙunsar 0.5, 0.75 da kuma 1.5 ml. The mafi ƙasƙanci kashi m zuwa 22 micrograms na follitropin Alfa (300 Iu), matsakaici - 33 MG na aiki sashi (450 Iu). The most adadin aiki wakili kunshe ne a cikin 1.5 ml - 66 micrograms ( "Gonal-F 900"). A farashin da miyagun ƙwayoyi dogara da taro na aiki abu.

Pen yana na musamman jin da sikelin, sa ka ka sarrafa kashi. A wannan nau'i na magani saya mafi riba godiya ga daban-daban dosages. A abũbuwan amfãni iya dangana, kuma babu bukatar shirye-shiryen da wani bayani da kowane allura.

Lyophilizate ga shirye-shiryen da mafita ga allura aka diluted da ruwa kafin kowane magudi. The bukata sashi na pre-calculates wani gwani ga kowane mutum hali.

Ta yaya ne lura da "Gonalom-F"?

A cikin rashi na ovulation far fara a lokacin makon farko na hailar sake zagayowar, bayar yau da kullum sananniya (wasu yiwu mita sabawa). A tsari na kara kuzari da ya kamata a aiwatar a karkashin iko da duban dan tayi nazarin, wanda ba ka damar sarrafa girman da follicles. An fara kashi - 0,13-0,25 ml miyagun ƙwayoyi "Gonal-F 75". Price bayani dauke da 5.5 MG na follitropin Alfa, shi ne mafi ƙasƙanci da kuma shi ne a kusa da 110 rubles. Kara da kashi fiye da 1-2 makonni zuwa 225 Iu (matsakaicin).

Idan a cikin wata daya da magani ba ya ba da sakamako mai kyau, miyagun ƙwayoyi far ya kamata a katse. na farko sashi za a karu domin kara magani.

Lokacin da bukatar sarrafawa ovarian hyperstimulation miyagun ƙwayoyi ne gudanar a wani sashi na 150-225 Iu. A kalla kullum kashi kada wuce 450 Iu. Far ta fara da kwanaki 2-3 na hailar sake zagayowar. Da taimakon duban dan tayi gwani zai saka idanu da girma da follicles. A tsawon lokaci da magani iya zama daga 5 zuwa 20 days. Bayan na karshe jiko, 48 hours daga baya, allura, mutum chorionic gonadotropin.

Mutanen da suka da matsaloli tare da aiwatar spermotogenez kuma ya nuna kara kuzari. "Gonal-F" a wannan yanayin da ake amfani a hade tare da mutum chorionic gonadotropin. Saba magani regimen ne subcutaneous allura daga cikin miyagun ƙwayoyi sau uku a mako (kashi 150 Iu). Duration na far ya kamata a kalla 4 watanni, bayan da wani mutum yana bukatar a yi nazari. Tare da kadan, ko kuma babu wani ci a sakamakon magani iya mika wa watanni 18.

dosing

A farko allura na miyagun ƙwayoyi ya zama wani gwani a wani asibiti. Bayan ya umurci, a nan gaba da haƙuri iya amfani da alƙalami da yin harbi, "Gonal-F." Dole ne na farko zama Mai ƙididdigewa ga umarnin da miyagun ƙwayoyi.

Da wadannan shawarwari ga m amfani da miyagun ƙwayoyi:

1. Kafin ta caka, "Gonal-F", ya kamata su wanke hannuwansu sosai tare da sabulu da kuma ruwa da yiwu kara sarrafa antiseptic.
2. Bazu a kan tsabta surface bukata abubuwa: alkalami sirinji, vial na foda da kuma ruwa ga allura, barasa swabs.
3. Wajibi ne a shirya alkalami, cire hula, saita ake so sashi da kuma hašawa da allura.
4. Lyophilisate (foda) diluted da ruwa ga allura ta hanyar gabatar ruwa zuwa cikin vial da bushe abu. A roba cover dole ne huda allura bude wani kwalban ba lallai ba ne. The ruwa ya kamata a gabatar sannu a hankali.
5. Yana da su gwada a cikin iska sirinji har da ake bukata kashi, sa allura a cikin vial tare da wani bayani da (a baya juya juye), don gabatar da iska da kuma gwada da ake so adadin miyagun ƙwayoyi.
6. A sirinji ya kamata ba iska kumfa. Domin mu rabu da su, kana bukatar ka matsa yatsa a kan ganuwar da sirinji da kumfa matsawa zuwa saman. Sa'an nan wajibi ne a tura plunger kuma a kwato haddi iska.
7. Skin ya kamata a bi da wani maganin antiseptik (barasa) a allura shafin.
8. A allura da aka yi subcutaneously a 45 ko 90 digiri. Sharply zuwa latsa plunger ba lallai ba ne. Da miyagun ƙwayoyi ne a gudanar sannu a hankali.
9. Domin gwamnati "Gonal-F" via sirinji alkalama ya isa ya danna fara button. Da allura a cikin wannan na'urar ne na bakin ciki da kuma kananan, don haka da zafi m ko kusan fakowa ba.
10. Bayan da allura zuwa shafin na allura kamata a tare da wani auduga swab tsomasu a tsanake cikin antiseptic.
11. Yarwa sirinji jefar bayan hanya.
12. Tare da allura-sirinji iyawa dole ne a cire, ya sa a kan hula. Ga na gaba magudi wajibi ne a yi amfani da wani sabon allura, wanda yazo da cikakke tareda miyagun ƙwayoyi.

illa

Shiri "Gonal-F" na iya haifar da illa a lokacin da magani. Wasu mata lura da wadannan cututtuka:

• Haihuwa tsarin - sau da yawa ci gaba ovarian cysts.
• A mummunan sakamako daga cikin miyagun ƙwayoyi iya shafar gabobi na narkewa kamar fili. An bayyana a cikin bayyanar tashin zuciya, amai, zawo, da rashin jin daɗi da kuma zafi a ciki.
• A allura site iya faruwa busa ko redness na fata.
• lokuta na rashin lafiyan halayen ne quite rare: rash, itching, wahalar numfashi, kurji.
• A wani ɓangare na tsakiya m tsarin - iya zama mafi m ciwon kai.
• Kalla sau da yawa akwai lokuta na mummunan tasiri a kan zuciya da jijiyoyin jini tsarin (thromboembolism).

Umurnai "Gonal-F" na nuna cewa maza da magani iya bayyana kuraje, dan kadan ya karu jiki nauyi. Akwai rare lokuta na varicocele, gynecomastia.

contraindications

Da miyagun ƙwayoyi yana da karfi da tasiri a jiki da kuma saboda haka ba za a iya gudanar ba tare da kafin magani. The aiki abu da kuma ƙarin aka gyara da wasu gazawa a lokacin da amfani. A likita ya kamata dauki wannan a cikin lissafi da kuma daidaita da magani regimen.

Umurnai "Gonal-F" yayi kashedin cewa da miyagun ƙwayoyi da aka haramta yin amfani da ga mutane da rashin ha} uri, ko hypersensitivity to abubuwa a cikin halitta. A wannan yanayin, zai iya ci gaba mai tsanani rashin lafiyan dauki ko wasu rikitarwa. Har ila yau Contraindications sun hada da:

• Igiyar ciki na jini da ba a sani ba etiology.
• Oncologic Pathology na ciki al'aurar.
• Harben ovarian cysts cewa sun ci gaba a bango na polycystic.
• Pregnancy kuma lactation.
• Nakasar munanan na gabobin, wanda suke hannun riga da ciki.

A gwani daukan la'akari duk comorbidities da suke samuwa a cikin haƙuri na tarihi. A wasu yanayi, babu bukatar yin amfani da kayan aikin, "Gonal-F." Price of magani dogara da duration na jiyya da kuma sashi daga cikin miyagun ƙwayoyi, amma ko da tsada magani ba kawo sa ran sakamakon a irin wannan pathologies kamar igiyar ciki fibroids, wanda bai kai ba menopause, toshewa da fallopian shambura.

Features na aikace-aikace

Kafin ka sanya wani magani don ta da ovulation ko spermatogenesis tsari, wani likita kwarewa a lura da rashin haihuwa, ya kamata su gudanar da likita ganewar asali ma'aurata, don taimaka sarauta daga gaban contraindications da kuma bukatar magani. Shi ne kuma dole da kuma sashi makirci za a shigar.

Marasa lafiya da suke sha ruri "Gonalom-F" kafin IVF qara damar samun ciki tare da tagwaye. The likita da aka zamar masa dole ya sanar da mace kafin a fara jiyya.

Lokaci daya da yin amfani da miyagun ƙwayoyi da sauran jamiái cewa tasiri cikin ci gaban da follicles, zai iya tsokana ci gaban hyperstimulation. Cikin shakka daga far wajibi ne a gudanar da ultrasonic bincike da kuma saka idanu ci gaban da follicles.

"Gonal-F": da farashin da kuma sake dubawa

Italian miyagun ƙwayoyi zuwa ta da ovulation yana da riga na dogon lokaci wajabta domin lura da rashin haihuwa a maza da mata. Wannan shi ne daya daga cikin mafi inganci kayayyakin aiki, (da yawa likitoci koma zuwa gare shi a matsayin "m manyan bindigogi"). "Gonal-F" nuna tabbatacce sakamakon ma a lokuta inda wasu a san nufin kasance m. Ainihin mulki da za a bi da marasa lafiya, da yake a cikin cikakken kiwon lafiya kula da aiwatar da tsufa da follicles da kuma spermatogenesis.

A lura sashi iya canja a karami da kuma a cikin wani babban hanya. A kudin da miyagun ƙwayoyi dabam daga 1100 rubles. har zuwa 16 000 rubles. ( "Gonal-F" 900 Iu). Bugu da kari ga yin amfani da tsada kayan aikin, shi ne ya zama wajibi su bi wasu sharudda a cikin abinci da kuma gaba daya kashe takarce abinci, Semi-ƙãre kayayyakin.

A lokacin far, haramta ya sha barasa, wanda yana da mummunan tasiri a kan maniyyi samar, shafi na pituitary gland shine yake da hypothalamus, disrupting da metabolism na jima'i steroids. Karuwan ji na ƙwarai, a cikin maniyyin da nicotine.