Erythremia - menene wannan? mataki eritremii

Erythremia - wani irin jini cuta halin da yaduwa (overgrowth) na erythrocytes da alama karuwa a yawan sauran sel (leucocytes, platelets). Shin a kullum, sau da yawa benign cuta ne quite rare. Shi ne dai zai yiwu degeneration na kirki m cutar sankarar bargo. Erythremia - wata cuta wadda bata da lafiya game da 4 mutane daga mutane miliyan 100 a shekara. Yana ba ya dogara ne a kan jinsi, amma shi ne yawanci kamu a mutane mazan da mazan. Duk da yake lokuta ya ruwaito da cutar da kuma a ƙaramin shekaru daban-daban, sau da yawa mata.

Erythremia (code ICD10 - S94.1) yana mai dagewa hanya.

Maikacin jini da kuma inji na cuta

eritremii inji tasowa kamar haka.

Red jini Kwayoyin - ja da maikacin jini, wanda babban aiki - ne kai daga oxygen zuwa duk Kwayoyin na jikin mu. Su ake samar a cikin bargo, saifa, da hanta. Bargo ne a cikin dogon kasũsuwa, ashe, vertebrae, hakarkarinsa, sternum, kuma kwanyar ƙasũsuwa. 96% na ja jini Kwayoyin suna cike da haemoglobin, wanda daukawa fitar numfashi aiki. Red launi ba su da baƙin ƙarfe. Red jini Kwayoyin suna kafa ta yin amfani da kara Kwayoyin. Su rarrabe ikon - da ikon zuwa raba (haifa), ya canza kama zuwa wani cell.

Ƙasusuwan ma ne rawaya da kuma bargo, wanda aka wakilta m nama. Ya fara nuna jini abubuwa ne kawai a matsananci yanayi, a lokacin da wasu kafofin na hematopoietic ba yi da ayyuka.

Erythremia (ICD-10 - International Nau'in Cututtuka, a cikin abin da code sanya wa wannan rashin lafiya 94,1 C) - wata cuta pathogenesis ba tukuna gane. Ga dalilai har yanzu ba su cikakken tãtacce da likitoci, jiki zai fara zuwa vigorously nuna ja jini Kwayoyin cewa an daina shige zuwa cikin jini, da kara jini danko, da kuma fara da nunawa jini clots. A tsawon lokaci, da kara hypoxia (oxygen yunwa). Kwayoyin ba sami isasshen abinci mai gina jiki, a matsalar aiki na samfur na faruwa a cikin sauran tsarin na jiki.

A 'yan ban sha'awa facts game eritremii

1. Erythremia - wannan shi ne wani benign cuta daga duk leukemias. Wannan shi ne lokaci mai tsawo yana m da kawai daga baya kaiwa zuwa rikitarwa.
2. Yana iya zama asymptomatic kuma ba ya sanar da kansa ga mutane da yawa da shekaru.
3. Duk da ya karu matakin na platelets, marasa lafiya yiwuwa matsanancin zub da jini.
4. Erythremia yana da iyali tarihi, don haka idan wani iyali yana da wani rashin lafiya, hadarin bayyanar dangi karuwa.

dalilan eritremii

Kamar sauran iri cutar sankarar bargo, erythremia har yanzu ba cikakken gane, da kuma dalilan da ta abin da ya faru ba saukar. Duk da haka, bayyana abubuwan da suka dace da ta fitowan:

1. Kwayoyin predisposition.
2. Mai guba abubuwa makale a cikin jiki.
3. Ionizing radiation.

kwayoyin predisposition

Shi ba a san daidai abin da gene maye gurbi sa bayyanar eritremii, duk da haka, ya gano cewa, a cikin iyali cuta na faruwa akai-akai isa a gaba zamaninsu. Da alama na bunkasa cutar ne ya karu da sau da yawa, idan wani mutum ne wahala:

• Down ciwo (take hakkin da fuska da wuya, na cin gaba da bata lokaci).
• Klinefelter ta ciwo (yiwu disproportionate adadi da kuma raya ci gaban jinkiri);
• Bloom ciwo (low tsawo, pigmentation a kan fuska da kuma ta disproportionate cin predisposition zuwa oncological cututtuka).
• Marfan ciwo (cuta da connective nama).

Predisposition zuwa eritremii bayyana ta da cewa da kwayoyin salula kayan (ciki har da jini guda ɗaya) ne m, don haka da wani mutum ya zama mai saukin kamuwa zuwa waje mummunan tasiri na - gubobi, radiation.

radiation

Ko da X-ray, kuma gamma-haskoki suna partially samamme ta jiki, shafi kwayoyin Kwayoyin. Su mutu, ko kuma mutate.

Duk da haka, ya fi iko rediyoaktif radiation samu da mutanen da suka yi wa ciwon daji jiyyar cutar sankara da cutar, kazalika da waɗanda suka kasance a cibiyar na ikon shuke-shuke ko atomic bama-bamai.

mai guba abubuwa

Lokacin da ingested, za su iya haddasa kwayoyin maye gurbi na sel. Wadannan jamiái suna kira sinadaran mutagens. Bayan da yawa karatu, masana kimiyya sun gano cewa marasa lafiya eritremii tuntube da wadannan abubuwa kafin ci gaban da cutar. Wadannan abubuwa sun hada da:

• benzene (a samu a cikin abun da ke ciki na fetur da kuma da yawa sinadaran kaushi).
• antibacterial jamiái (musamman, "Chloramphenicol");
• cytostatic jamiái (anti-ƙari).

Eritremii saukarwa da su cututtuka

Erythremia yana da wadannan matakai: na farko, fãta shimfiɗaɗɗa kuma m. Kowace daga cikinsu yana da kansa bayyanar cututtuka. A farko mataki na iya wuce shekaru da dama ba tare da nuna wani tsanani bayyanar cututtuka. Ƙananan cututtuka marasa lafiya yawanci zargi a kan sauran, kasa tsanani cututtuka. Bayan duk, ko da likitoci sau da yawa ba biya isa hankali ga ajizai jini gwajin.

Idan akwai wani primary erythremia, jini gwaje-gwaje da matsakaici sabawa daga na kullum.

A can farko aka kuma halin da gajiya, juwa ko jiri, tinnitus. A haƙuri barci talauci, ji sanyi a cikin extremities, akwai an busa na hannuwansa da ƙafafunsa. A karu a shafi tunanin mutum da yi. Babu waje manifestations da cutar yet. Ciwon kai ba a dauke wani takamaiman alama da cutar, amma yana faruwa a can farko saboda matalauta zagayawa a cikin kwakwalwa. Saboda wannan dalili, rage hangen nesa, da hankali da kuma hankali. Lokacin da ganewar asali "erythremia" bayyanar cututtuka da cutar a cikin mataki na biyu da nasu halaye - zub da jini gumis, zama a kananan hematoma. A kan ƙananan kafar iya bayyana duhu aibobi (thrombosis cututtuka), kuma ko da miyakunsa. Girma gabobin da cewa samar da ja jini Kwayoyin - da baƙin ciki, kuma hanta. Saboda ci gaban da cuta mai ƙãruwa Lymph nodes.

Eritremii mataki na biyu zai iya šauki game da shekaru 10. The nauyi ne rage muhimmanci. A fata samun ceri sautin (yawanci hannuwansu da ƙafãfunsu), da taushi palate canjãwa launi, m - rike ta haihuwa launi. Itching dame haƙuri wanda aka Littafi bayan hotuna a dumi ko zafi ruwa. Jikin zama kumbura jijiya daga wani overabundance na jini, musamman a cikin wuyansa. Idanu da jũna bloodshot, saboda erythremia, da bayyanar cututtuka na wanda sun bayyanu isasshen a cikin mataki na biyu, na inganta jini ya kwarara zuwa tasoshin ido.

Saboda matalauta jini wurare dabam dabam a cikin capillaries bayyana zafi da kona abin mamaki a cikin yatsunsu da yatsun kafa. A ci-gaba lokuta zama na fili tsiatonicheskie spots a kan su.

Akwai kashi da epigastric zafi. Hadin gwiwa zafi dangantawa da gouty yanayi na wuce haddi uric acid. A general, da aiki da kodan zai lalace, sau da yawa kamu pyelonephritis kuma samu uratovye koda duwatsu.

A juyayi tsarin shan wahala. A haƙuri juyayi, ya yanayi ne m, halin da tearfulness da kuma canje-canje akai-akai.

danko na jini ƙaruwa, wanda results a cikin bayyanar jini clots a daban-daban jijiyoyin bugun gini yankunan. Har ila yau, akwai hadarin tasowa varicose veins ci gaba.

Gargadi! Marasa lafiya na iya ma sha daga hauhawar jini, da kuma bude na ulcers a cikin duodenum. Wannan shi ne saboda wani karu a cikin jikin ta defenses da kuma kara yawan Helicobacter pylori - shi ne wannan kwayoyin sa ulcers.

Eritremii The uku mataki ne halin da pallor na fata, m faintness, wani rauni da sluggishness. Ya lura shafe tsawon zub da jini a lokacin kadan rauni, aplastic anemia saboda ƙananan haemoglobin matakai a cikin jini.

The uku mataki eritremii: Bayyanar cututtuka da kuma Matsalolin

Erythremia - jini cuta, wanda a cikin na uku mataki zama m. A wannan mataki, da bargo Kwayoyin sha fibrosis. Ya ba zai iya samar da ja da maikacin jini, don haka dokoki na jini Kwayoyin fada, wani lokacin ga m Manuniya. A cikin kwakwalwa, akwai foci na softening, hanta fibrosis fara. A gall mafitsara ne a lokacin farin ciki, da danko sosai bile kuma pigment duwatsu. A sakamako ne cirrhosis da jijiyoyin bugun gini occlusion.

A baya can, shi da aka ƙara thrombus iya zama dalilin mutuwar marasa lafiya da erythema. jirgin ruwa ganuwar ne batun sauya, akwai wani blockage na jijiyoyinmu a cikin kwakwalwa, saifa, zuciya da kuma kafafu. Taso occlusive cuta - blockage na kayayyakin da kafafu da hadarin cikakken ƙanƙancewa.

Koda lalacewa. Saboda ci gaban da uric acid marasa lafiya fama da hadin gwiwa zafi gouty hali.

Gargadi! Lokacin da eritremii kafafu da kuma makamai sau da yawa canza launi. A haƙuri ne yiwuwa ga mashako da kuma colds.

cutar

Erythremia - wani jinkirin cuta. Haka kuma cutar ta zo a cikin ta mallaka jinkirin, shi ne farkon mai m da unobtrusive hali. Marasa lafiya sau da yawa rayuwa shekaru da dama ba tare da biyan hankali ga qananan cututtuka. Duk da haka, a mafi tsanani lokuta saboda jini clots mutuwa na iya faruwa a cikin 4-5 shekaru.

Tare da eritremii ƙara baƙin ciki. Ware form tare da cirrhosis rauni da kuma diencephalon. A lokacin rashin lafiyan cututtuka, da kuma dauke da kwayar cutar da rikitarwa za a hannu, marasa lafiya sau da yawa ba zai iya jure wasu kwayoyi kungiyar sha wahala daga urticaria da sauran fata cututtuka. Course da cutar da wahala ta co-faruwa yanayi, ganewar asali ne yawanci yi bayan tsofaffi.

Posteritremichesky myelofibrosis - wani abu akan sake haihuwa na kirki hanya na rashin lafiya a m. A yanayin ne na halitta a cikin marasa lafiya suka tsira zuwa wannan lokaci. A wannan yanayin, da likitoci yarda cewa erythremia samu ƙari hali.

Yana da muhimmanci ga daidai gane asali erythremia kuma dace magani. Ganewar asali hada da wani yawan karatu.

Analysis na jini a eritremii

Lokacin da ganewar asali "erythremia" jini gwajin sigogi wanda ke da muhimmanci ga ganewar asali, da aka yi a da fari. Farko, kuma farkon wannan wata na kowa jini gwajin. Shi ne mahaukaci a shi ya zama na farko ƙararrawa kararrawa. Yana kara yawan ja jini Kwayoyin. Da farko, shi ne ba da muhimmanci, duk da haka, tare da ci gaba da cutar da aka kara ƙara, kuma da dama a kan na karshe mataki. A al'ada erythrocyte matakin a cikin jini na mata ne daga 3.5 zuwa 4.7, da kuma maza - daga 4 zuwa 5.

Idan kamu erythremia, jini gwajin Figures wanda ya nuna wani karuwa a ja da maikacin jini, ya ce game da shi daidai karuwa a haemoglobin. Hematocrit nuna jini ta ikon kawo oxygen, ya karu zuwa 60-80%. Launi index aka canza ba, amma na uku mataki na iya zama wani abu - na al'ada, ta ƙara ko rage. Platelets da farin jini Kwayoyin karu. Farin jini Kwayoyin girma sau da yawa, da kuma wani lokacin more. Halitta eosinophils (wani lokacin tare da basophils) qara. Tsanani ƙãra platelets. Erythrocyte sedimentation kudi - ba fiye 2 mm / hour.

Alas, cikakken jini count, ko da muhimmanci ga na farko ganewar asali, kadan bayanai, da kuma kawai a kan tushen da ya ganewar asali ba sa.

Sauran karatu a eritremii

• Biochemical bincike na jini. Its Babban burin - don ƙayyade yawan baƙin ƙarfe a cikin jini da kuma matakin na hanta aiki gwaje-gwaje - AST da Alt. Suna saki daga hanta a cikin halakar da Kwayoyin. Tabbatar da dalilin da adadin bilirubin nuna tsananin aiwatar da erythrocyte halaka.
• Bargo huda. Analysis dauka tare da allura da aka saka a cikin fata da periosteum. Hanyar nuna halin hematopoietic Kwayoyin a cikin bargo. Bincike ya nuna da yawan Kwayoyin a cikin bargo, gaban ciwon daji Kwayoyin kuma fibrosis (girma na connective nama).
• Lokacin da ganewar asali "kullum erythremia" kuma yi awon alamomi, da kuma na ciki duban dan tayi. Duban bayyana cunkoson ababen hawa gabobin, kara girman hanta da saifa, kazalika da Aljihuna na fibrosis a cikin su.
• Doppler nuna jini ya kwarara gudu da kuma taimaka wajen gano jini clots.

eritremii magani

Ya kamata a lura cewa sau da yawa erythremia progresses sannu a hankali, kuma yana da kirki hanya. Da farko, likitoci rika yin salon canje-canje - more zama a waje, ya yi tafiya, don samun tabbatacce motsin zuciyarmu (endorfinoterapiya wani lokacin kai mai girma sakamakon). Foods dake dauke da wani bangare na babban adadin na baƙin ƙarfe da kuma bitamin C, ya kamata a cire.

A mataki na farko da cutar babban manufar da ganewar asali "erythremia" - jini sigogi rage al'ada haemoglobin - har zuwa 150-160, da kuma hematocrit - to 45-46. Yana da muhimmanci ga negate da matsalolin da ya sa da cutar - cuta da jini wurare dabam dabam, zafi a cikin yatsunsu, da dai sauransu ...

Maido hematocrit da haemoglobin taimaka zub da jini, wanda a cikin wannan yanayin da ake amfani da su a wannan rana. Duk da haka, wannan hanya da aka yi a cikin tsarin na gaggawa, domin shi stimulates da bargo da kuma thrombopoiesis aiki (platelet samuwar tsari). Akwai kuma wata hanya da ake kira eritrotsitaferez, wanda shi ne ya tsarkake da jinin da ja jini Kwayoyin. A wannan yanayin, da jini jini ya zauna.

magani

Cytostatics - wannan yanayi antitumor kwayoyi wanda ake amfani a rikitarwa eritremii - ulcers, thrombosis, cerebral wurare dabam dabam cuta tasowa a cikin mataki na biyu na cuta. "Mielosan", "busulfan", hydroxyurea, "Imifos" rediyoaktif phosphorus. A karshen an dauki tasiri da cewa tara a cikin kasusuwa da damuarn kwakwalwa aiki.

Steroids wajabta hemolytic anemia na autoimmune asalin. "Prednisolone" ne musamman rare. Idan magani ba ya bayar dacewa da sakamakon, rubũta tiyata don cire baƙin ciki.

Don kauce wa baƙin ƙarfe rashi, da baƙin ƙarfe kari iya wajabta - "gemofer", "Totem", "Sorbifer".

Wadannan kungiyoyin na kwayoyi suna wajabta matsayin da ake bukata:

1. Antihistamines.
2. Ragewan jini.
3. Anticoagulant (jini thinning).
4. Hepatoprotectors.

Erythremia, magani ne sau da yawa da za'ayi a asibiti - shi ne mai tsanani cutar da cewa yana sa mai yawa rikitarwa. Yana da muhimmanci a gane shi a farkon yiwu kuma fara ta da magani.