Da miyagun ƙwayoyi "salofalk": analogs da umarnin don amfani

A jikin mutum ne fafitikar da wani iri-iri na cututtuka, sauki da hadaddun, cikin ransa. Nisa daga kasancewa mafi yawan 'yan a cikin jerin kiwon lafiya matsalolin zauna kumburi hanji cuta. Don yaki tare da su wajen samar da wata dama daban-daban magunguna tare da daban-daban ka'idojin aikin.

Abu mesalazine ne babba bangaren isasshe babban rukuni na magunguna ( "salofalk" analogs) don yaƙar takamaiman kumburi hanji cututtuka.

Abun da ke ciki "salofalk", pharmacodynamics

Kamar yadda aka ambata a baya, da babban aiki sashi ne mesalazine medicament. Kamar yadda karin hidima mai yawan gyara, musamman, kamar sodium carbonate, glycine, povidone, microcrystalline cellulose, silicas, kuma titanium, alli stearate, croscarmellose sodium, hypromellose babban butylmethacrylate copolymer.

"Salofalk" (granules, Allunan, suppositories, dakatar) inhibits (depresses) tafiyar matakai na neutrophil da lipoxygenase kira a cikin mutane prostaglandins da leukotrienes. The aiki abu rage kudi na hijirarsa, phagocytosis da degranulation na neutrophils, rage mugunya lymphocytes. Bugu da ƙari, medicament ne iya dauri free radicals da baya hallaka su, Ina nufin farfado antioxidant sakamako. Har ila yau mesalazine iya dauri da free radicals kafa daga amsawa oxygen jinsi.

Alamomi ga yin amfani da

Babban yankin a cikin abin da ya sami yin amfani da "salofalk" - wani magani domin ulcerative colitis da Crohn ta cuta.

A farko cuta ne na kullum kumburi tsari ya ba tukuna tãtacce da yanayi. Its ci gaba ne ya sa ta wani hulda da kwayoyin dalilai da kuma muhalli da yanayi.

Crohn ta cuta za a iya halin da na kullum granulomatous kumburi da gastrointestinal fili. Wannan tsari na iya kama dukan sassa na narkewa kamar tsarin, shi rinjayar duk yadudduka na narkewa kamar bututu. A sakamako iya zama da ci gaban lymphadenitis, ulceration da scarring na hanji bango ne ba.

Form miyagun ƙwayoyi saki

Masana'antun bayar da abokan ciniki da miyagun ƙwayoyi "salofalk" (irin wannan a cikin wannan girmamawa iya bambanta) a cikin 'yan daban-daban siffofin samar.

A cikin kwamfutar hannu tsari iya ƙunsar 250 ko 500 MG na babban aiki bangaren - mesalazine. A daya sachet iya ƙunsar 500 MG ko 1 g na babban abu. A medicament a cikin nau'i na suppositories (suppositories for rectal gwamnati) ne kuma samuwa a cikin biyu dosages - 250 da kuma 500 MG na babban bangaren. Har ila yau, za a iya saya a Pharmacy da kumfa dakatar for rectal gwamnati. A mafi tasiri ga kowane mutum haƙuri saki form zai taimake ka ka zabi zalunta likita.

Allunan dosing regimen

Standard sashi na manya - sau uku a rana 500 MG. Idan kamu da tsananin digiri na cuta, da halartar likita na da hakkin ya kara da kashi to 3-4 g per day. A hanya na far iya wuce daga 2 zuwa 3 watanni. Idan magani ake dauka a matsayin rigakafi, shi ne yake aikata ta a misali makirci (1.5 g a uku allurai a lokacin da rana).

Matasa marasa lafiya 'salofalk "User Application (analogs iya bambanta a sashi regimen) ya bada shawarar samar daidai da nauyin da yaro. Babies tare da jiki nauyi ba wucewa 40 kg, likita ya furta 250 MG na da miyagun ƙwayoyi sau uku a rana. Idan jariri nauyi ya wuce 40 kg, shi nuna wannan sashi kamar yadda na manya: 500 MG sau uku a rana.

Allunan mafi kyau dauka bayan kammala abinci, ba tauna da kuma sha yalwa na ruwa (zai fi dacewa ruwa).

A makirci na granules

Wannan saki nau'i na da miyagun ƙwayoyi "salofalk" (granules) da aka nada ta hanyar halartar likita musamman akayi daban-daban, dangane da total na asibiti hoto na haƙuri da kiwon lafiya. A mafi yawan lokuta a lokacin exacerbation na ulcerative colitis da haƙuri da ake sa a yi maka a kashi na 500 MG ko 1 g sau uku a lokacin da rana (t. E. A kullum girma na medicament ne daga 1.5 zuwa 3.0 g). Za ka iya daukar wani guda kashi sau 3 bags. Idan da mãsu haƙuri ne a gafarta musu, "salofalk" kai a kashi na 1.5 g per day: shi za a iya raba 3 allurai dauka ko duk da miyagun ƙwayoyi a lokaci daya.

Idan muna magana ne game da wani exacerbation na ulcerative colitis a yara (daga 6 shekaru da mazan), da halartar likita ta zayyana da miyagun ƙwayoyi a cikin kudi na 30-50 MG mesalazine da 1 kg na nauyi. All kashi iya dauka a lokaci daya, ko kuma zuwa kashi 3 allurai a ko'ina cikin yini.

A granules ya kamata a sa a kan harshe, da, ba tare da daukan taban, hadiya. Da miyagun ƙwayoyi kamata sha yalwa da ruwaye. Don da warkewa sakamako ya resistant granules ya kamata a dauka a kai a kai da kuma consistently. M mataki na ulcerative colitis yawanci mutu a cikin 2-3 watanni, mafi m kullum kashi rage zuwa 1.5 g per day.

Manufa da kuma yanayin na aikace-aikace na suppositories

"Salofalk" (kyandirori) umurci manual bada shawarar a sashi na 500 MG (1 rectal suppository 500 MG ko 2 - 250 MG) sau uku a rana. Idan cuta a cikin m mataki, kullum kashi za a iya ninki biyu. Idan wani haƙuri da ake sa dogon hanya na far ko manufa liyafar - zalla prophylactic (komowa na rigakafin), da saba kashi a cikin wannan yanayin ne 250 MG (1 kyandir) sau uku a lokacin da rana.

Ga matasa marasa lafiya sashi dogara a kan jiki nauyi. Yara yin la'akari kasa da 40 kg "salofalk" (kyandirori) umarnin don amfani da shirya sanya ½ sashi domin ya fara tasawa, t. E. 250 MG sau uku a rana. Idan yaro ya nauyi ya wuce 40 kg, shi ne sanya wa miyagun ƙwayoyi sashi kamar yadda for adult marasa lafiya (sau uku a rana 500 MG).

rectal dakatar

Drug "salofalk" - dakatar yana samuwa a cikin kwalabe azurta rectal gwamnati. A hanya aka yi sau daya a yamma kafin lokacin kwanta barci. A haƙuri kafin gwamnati da miyagun ƙwayoyi ne shawarar da su saki da hanjinsu. A kullum adadin da miyagun ƙwayoyi da aka zaba bisa haƙuri da nauyi (a cikin sharuddan na 30-50 MG / kg). Idan da cutar mai tsanani ce, ko da yake a kan aiwatar da ake kara, matsakaicin kashi a lokacin da rana za a iya isa har zuwa shekaru 3 zuwa hana kōmōwa masana yawanci bayar da shawarar shan "salofalk" da baki (Allunan). A wannan yanayin da kashi (yau da kullum) suna kuma sanya wa nauyi na - 15-30 MG / kg jiki nauyi. All kullum girma na magani a ko'ina cikin yini bada shawarar da za a kasu kashi biyu, saukarwa.

Contraindications don samun "salofalk"

Amfani da miyagun ƙwayoyi "salofalk" (analogues - shi ne ba togiya) ne contraindicated ga mutanen da tare hypersensitivity ga babban da kuma karin aka gyara daga cikin miyagun ƙwayoyi. Yana da unacceptable sanya Allunan zuwa yara a karkashin 3 shekara, granules - to 6-shekara. Ba ka da ka dauki magani don a haƙuri wahala daga mai tsanani na koda ko hanta insufficiency.

Kada Ka sanya "salofalk" mutanen da suke da hali ya ci gaba zub da jini, daban-daban hematopoietic tsarin cututtuka. Wahala daga hemorrhagic diathesis yanayin miki cutar da wani gastrointestinal fili kuma kada kai magani a kan tushen da mesalazine.

A granules unacceptable medicament gudanar don marasa lafiya fama da phenylketonuria (hereditary cuta hade tare da mai illa metabolism na phenylalanine take kaiwa zuwa tsanani CNS raunuka a cikin nau'i na ilimi tawaya).

Game da ciki da kuma lactating mata, da yin amfani da miyagun ƙwayoyi a farkon watanni 3 na ciki ya kamata a sami kuɓuta ta m alamomi. A cikin 2-3 awo ganawa "salofalk" mai yiwuwa ne kawai a lokuta a lokacin da ake zargin tabbatacce sakamako a kan kiwon lafiya na mace mamaye yiwu hadarin ga jariri. Bisa ga wannan shaidar ke na yarda ga amfani da granules 'salofalk "lactation. Duk da haka, idan yaro yana da zawo, shi wajibi ne ta yi watsi nono. Kuma a general, optimally shirya kafin farko na ciki, a daina shan "salofalk" ko, a kalla, da rage da kashi samu.

Zai yiwu illa

Side effects ne kusan duk wani magani. Akwai wani togiya da kuma "salofalk" (Rasha takwarorinsu kazalika). CNS illa ne yiwu bayyanar cututtuka kamar ciwon kai, dizziness, tremors, tinnitus, ciki, convulsions, paraesthesia. Gastrointestinal fili iya amsa ga yin amfani da "salofalk" da zafi a ciki, bloating, zawo, tashin zuciya da amai. Zai yiwu ci gaban hepatitis, hanta transaminase dabi'u canza. Cardio-jijiyoyin bugun gini tsarin iya samun tachycardia, jini shakka (hyper- ko hypotension), ciwon kirji, dyspnea.

A wasu lokuta, marasa lafiya za a iya ji a kan ci gaban myalgia, arthralgia. Bugu da kari, da miyagun ƙwayoyi zai iya sa anemia, leukopenia, thrombocytopenia, anuria, oliguria, hematuria, crystalluria.

Da dama rashin lafiyan halayen ne yiwu itching, fata na gaggawa, erythema, bronchospasm, pericarditis da myocarditis. A marasa lafiya da hypersensitivity zuwa mesalazine iya ci gaba cututtuka irin interstitial nephritis, nephrotic ciwo, m lokaci na pancreatitis. A wani raba rukuni na marasa lafiya "salofalk" (kama da nasa, kazalika) Yanã cututtuka kama da wani ciwo na tsari lupus erythematosus.

magunguna analogues

The "salofalk" isasshen yawa daga magunguna analogues na babban aiki bangaren. Ta yaya za a iya, misali, maye gurbin "salofalk" - kyandirori? Analogues, wanda sau da yawa cikin bukatun da masu amfani da kuma jinya an nada - shi ne suppositories "Pentas" da "Samezil". Wadannan magunguna babban aiki sashi ne mesalazine, don haka suna da kama da pharmacological effects a kan jikin mutum.

"Mesakol" - wani yadu amfani analog "salofalk" (a granules, Allunan).

Bayan aiki analog bangaren, akwai wani babban rukuni na kwayoyi da suke da irin wannan a warkewa sakamako. Wadannan kwayoyi na iya amince da wani sashe "Azathioprine" da "Alginatol", "hydrocortisone" da "Dexamethasone" "Diprospan" da "Irmalaks", "prednisolone" da "Sulfasalazine". Jerin ci gaba.

takamaiman shawarwari

Kafin ka fara jiyya da kuma a lokacin jiyya da kuma bayan ta ƙarshe azurtawa bayar da shawarar dauka na kowa jini da fitsari gwaje-gwaje. Har ila yau, kafin magani da kuma a kan aiwatar da shi wajibi ne don saka idanu da sigogi na aikin jiha na hanta. Kulawa da aka fi yi bayan kwanaki 14 bayan qaddamarwa na far, sa'an nan kuma wani 2-3 sau a kan jinkiri na 4 makonni. Idan gwajin sakamakon ne a cikin al'ada iyaka, sa idanu safiyo da za'ayi kowane watanni 3. Idan ba zato ba tsammani wasu irin sabawa za a lura a cikin bincike, shi wajibi ne a gudanar da wani iko da gwaje-gwaje nan da nan.

A da nada wani nau'i na magani "salofalk" (kyandirori, analogues na Allunan, granules, suspensions) zuwa marasa lafiya fama da Bronchial fuka, da likita ake bukata a hankali saka idanu da yanayin da marasa lafiya a lokacin far. Idan haƙuri yana da tarihin bayyana yiwuwar illa lokacin shan "Sulfasalazine" jiha na kiwon lafiya irin wadannan mutane ya kamata a kula a hankali a matakin farko na lura "Salofalk." Idan suka bayyana wani m rashin ha} uri halayen (convulsions, ciki zafi, rash, zazzabi), da amfani da miyagun ƙwayoyi ya kamata a daina amfani da nan da nan.

Lokacin da tuki ko ko yin ayyuka da cewa bukatar high gudun psychomotor halayen, marasa lafiya samun "salofalk", ya zama musamman da hankali.