Da miyagun ƙwayoyi "Gemaza": umarnin don amfani a ophthalmology da kuma sake dubawa

Mene ne manufar yin amfani da miyagun ƙwayoyi "Gemaza" a ophthalmology? Umarnin don amfani da manufar da magani aka jera a kasa. Za ka kuma koyi game da tsari na saki na ce wajen, contraindications zuwa ga yin amfani da illa.

Abun da ke ciki, bayanin da miyagun ƙwayoyi da kuma siffar

Shiri "Gemaza" (umarnin don amfani da kayan aiki da ake bukata don yin karatu) yana dauke da recombinant prourokinase, kazalika da irin ƙarin abubuwa kamar dextran 40 da sodium chloride.

A sayar da miyagun ƙwayoyi dauke zo a cikin wani nau'i na lyophilizate wanda shi ne wani farin amorphous ko porous taro, wanda ba shi da wani wari da kuma ne aka yi nufi ga shirye-shiryen da wani igiyar jini bayani.

Drug "Gemaza" a vials sanya daga gilashi sanya shi a cikin kwane-kwane na cell ko roba pallets, wanda aka rufe a kan a fakitoci na kwali.

Ya kamata ka kuma ce cewa wannan magani yakan haifar da wanzuwar musamman abu - ruwa da aka zuba a cikin vials.

Pharmacology ophthalmic miyagun ƙwayoyi

Ta yaya miyagun ƙwayoyi "Gemaza"? Umurnai na Amfani furta cewa mataki na wannan enzyme yana nufin saboda da aiki sashi - prourokinase. Yana da wani enzyme - serine protease. A sunadarai tsarin da abu ne guda-stranded kwayoyin (da kwayoyin nauyi na 54 daltons tysyachi) wanda ya hada da biyu polypeptide sarƙoƙi da cewa suna da alaka da wani disulfide gada da kwayoyin talakawa na 20 da kuma 34 tysyachi Daltons.

Ka'idar aiki na da kayan aiki bisa takamaiman ruri na hira da plasminogen cikin fibrinolytic jini aka gyara - fibrinolysin, da kuma ikon hallaka fibrin clots.

Sanadin motsi halaye na da miyagun ƙwayoyi

Ta yaya ne gida sha na da miyagun ƙwayoyi "Gemaza"? Umurnai na amfani shelanta cewa ganiya yawa daga cikin miyagun ƙwayoyi a cikin tsokoki na gani Gabar kai sa'o'i biyu daga baya, da kuma bayan wani rabin burbushi za a iya gano a cikin haƙuri na jini.

Recombinant prourokinase rabin rayuwa ne game da 6 hours. Ya kamata a lura da cewa saboda da yin amfani da karami allurai da miyagun ƙwayoyi a kai ta na tsari tasiri ne ba zai yiwu ba.

Drug "Gemaza": nadi (na nuni)

Amfani da rahoto nufin a ophthalmic yi saboda da high dace a cikin wadannan lokuta:

• a subretinal, preretinal da intraretinal hemorrhages.
• da kuma lokacin da hemophthalmus hyphema.
• tsakiyar venous thrombosis a cikin akan tantanin ido ko da rassan da tsakiyar jijiya occlusion.
• A gano fibrinoid ciwo na daban-daban asalin;
• su hana m matakai bayan antiglaukomatoznyh shisshigi.

Haramta yin amfani da bayani

A wasu lokuta, magani ya kamata ba za a wajabta "Gemaza"? Umurnai na amfani (injections ya kamata a yi kawai da wani gogaggen sana'a) maki to da wadannan hani:

• hanta cututtuka da cewa suna tare da pronounced cuta da hemostasis.
• hali ya zub da jini, ciki har da gaban hemorrhagic diathesis, hemophilia, thrombocytopenia, kuma haka a kan;
• CPR da sauran resuscitative hanyoyin yi ga fiye da minti 10.

• zub da jini daga gastrointestinal fili, ciki har da takardar sayen magani daga up to 28 kwana, da laka ko intracranial baki tare da sayen magani daga sama zuwa 56 kwanaki, babbar tiyata ko rauni da sayen magani daga up to 28 kwana.
• hudu aji cardiogenic buga (bisa ga Killip rarrabuwa).
• aiki nau'i na da tarin fuka.
• koda gazawar, sunã gudãna a cikin kullum form.
• huda manyan tasoshin, ciki har da subclavian jannayẽnsa.
• hemorrhagic (m) raunuka na akan tantanin ido.
• wani tarihin na haemorrhagic bugun jini ko gaban ta tarihi;
• hawan jinni rikicin.
• high systolic ko diastolic jini;
• kwayan ko kwayan endocarditis.
• hypersensitivity zuwa sodium chloride, prourokinase ko dextran 40;
• dissecting aortic aneurysm ko tuhuma daga gare ta,
• a lokacin daukar ciki.

Drug "Gemaza": umarnin don amfani da

Kamar yadda miyagun ƙwayoyi ya kamata a yi amfani da karkashin shawara? A saboda wannan dalili, da abinda ke ciki na 1 vial dole ne a diluted a 0.5 ml na 0.9% sodium chloride bayani. A sakamakon bayani ne daidai da wani kashi na 5 da dubu. ME.

A gabatarwar da wannan magani ya kamata a subkonyunktivalno (watau karkashin conjunctiva), ko parabulbarno (ie a yankin na ƙananan fatar ido).

A tsawon lokaci da far tare da wannan wakili ya 10 da allura kudi (ba more).

As "Gemazu" ya kamata a yi amfani da manufar wanka tare da hyphema ko m effusion na fibrin a cikin agara na gani jiki? Don yin wannan, kai 0.2 ml na cikin shirye-shiryen diluted da lyophilisate da kuma kawo 0.5 ml tare da 0.9% sodium chloride bayani.

Domin intravitreal gwamnati na medicament kamata a yi amfani da 0.1 ml na bayani da kuma tsarma shi zuwa 0.9 ml na 0.1-0.2% bayani daga sodium chloride. Irin wannan shiri za a iya amfani da a lokaci daya hemophthalmus daban-daban Farawa da fibrinoid ciwo.

Ba za mu iya ce cewa miyagun ƙwayoyi "Gamaza" (bayanin irin shirye-shiryen da aka gabatar a sama) ne sau da yawa amfani da matsayin prophylactic wakili don antiglaukomatoznyh adhesions bayan tiyata. Don wannan karshen shi ne diluted a cikin wannan rabo a matsayin cewa ga subconjunctival aikace-aikace. Bayan nan, da medicament aka gabatar a cikin tace kushin a farkon postoperative zamani.

Side effects da miyagun ƙwayoyi

A cikin shakka daga jiyya ba tare da "Gemaza" haƙuri iya ci gaba da wani rashin lafiyan dauki a cikin hanyar:

• redness da fata a kan fuska ko a allura site.
• edema.
• rashin lafiyan tenonita kamar yadda chemosis, m motsi na eyeball, da kuma conjunctival hyperemia.

Overdosing da hulda

A guda gwamnati da miyagun ƙwayoyi a karkashin shawara a sashi na fiye da 5 dubu. ME muhimmanci ƙara hadarin rashin lafiyan halayen da aka bayyana a cikin m events.

A lokacin tiyata da kuma a lokuta da yawan abin sama a lokacin jiyya da kayan aiki don rage hadarin hemorrhage ne kara da shawarar a yi amfani da medicament "Etamsylate" by intramuscular allura (a sashi na 250-500 MG).

Taba amfani da "Gemazu" alura "Kollalizina". A kan wasu thrombolytic amfani da wannan kayan aiki ya zama tare da taka tsantsan.

A wannan sirinji ba za a iya gauraye a lokaci daya biyu kwayoyi (ba domin "Dexamethasone").

takamaiman bayanai

Tare da ci gaban bradycardia ko hypotension kamata dakatar da gabatarwar da miyagun ƙwayoyi zuwa daidaita zuciya kudi da kuma jini.

Ophthalmic miyagun ƙwayoyi "Gemaza": reviews da kuma irin shirye-shirye

Abin da za a iya dauke su maye gurbin magani? Its analogs ne kwayoyi kamar "Actilyse", "Plasmin", "Metaliz" da "Trombovazim".

Abin da mutane suke cewa game da wannan kayan aiki, mutane suka sha wahala daga matsalolin da na gani gabobin? Mafi sau da yawa, wannan shiri na sake dubawa bar waɗanda suke amfani da shi tare da hemorrhages a ophthalmic yi. A lokaci guda, marasa lafiya da'awar cewa wadannan injections suna tasiri da ingantaccen. Kuma su ne tasiri da kuma cikakken jimre da aiki.

Duk da dukan wahala da likita hanya (irin injections quite m), marasa lafiya rika yi haƙuri, kuma ba su kawo su da yanayin kafin kau da vitreous jiki.

Kamar yadda na da korau da sake dubawa na wannan makaman, da mafi sau da yawa su suna hade da ci gaban illa, kazalika gaban wata babbar lamba na contraindications. Bugu da kari, marasa lafiya da yawa ga cewa kudin da miyagun ƙwayoyi "Gemaza" an overstated (Kudinsa 750-850 rubles).