Aspartate aminotransferase ya karu, abin da yake nufi, da dalilai

Jikin mu, watakila, za a iya daukan mafi "cigaba da fasaha", wanda Ya halitta Mother Nature. A da shi, kowane jiki ne musamman a cikin "tsarin" da damar, ya ba kamar yadda m kamar yadda shi ne mai daukan hankali. Kuma idan ka shiga cikin binciken na dukan kwayoyin, yana yiwuwa su hadu a babba yawan hadaddun sharuddan. Sau da yawa, da kiwon lafiya gwaje-gwaje za ka iya samun irin wannan unpronounceable magana kamar yadda aspartate aminotransferase karu. A halin yanzu, shi yana nufin da amino acid tsakiyan nonon topic. Yana da daraja don Masana wannan lokaci kadan kusa.

Abin da irin lokaci?

A karkashin ba kalmar da ake nufi wani enzyme wanda ke taka rawa a cikin tsakiyan nonon mata aiki, kusan duk wani amino acid a cikin jiki. Rage ya kira SGOT ko AST aka nuna a babban birnin kasar haruffa. A enzyme aka located a cikin kyallen takarda da yawa gabobin, kamar:

• hanta.
• zuciya;
• jijiya nama.
• koda.
• tsoka.
• pancreas.
• baƙin ciki.
• haske.
• kwakwalwa nama.

Haka kuma, mafi yawan enzyme a cikin tsokoki na zuciya, koda, jijiya Kwayoyin, hanta.

Saboda haka, ganewar asali na wani cuta dangantawa da waɗannan jikuna yana nufin cewa aspartate aminotransferase karu. A cikin huhu, saifa, kuma pancreas enzyme adadin ba haka ba ne manyan. Cikinsa da namiji jiki ne daban-daban daga mace high aiki ACT.

aiki AST

A enzyme ne sunadarin wanda aka bayar da salon salula nama na ciki gabobin. Da tsarin da aka kafa ta Rasha masana kimiyya a 70s. The aiki na enzyme ne don hanzarta biochemical halayen a cikin sel. Tare da sa hannu na bitamin B6, yana yiwuwa musayar amino acid. A cikin hadaddun canji na da yawa amino acid, ciki har da aspartic, da samuwar wani sabon fili. Yana da aka yi masa godiya da kira na glucose, wanda shi ne don haka wajibi ne ga jikin mu.

Features AST

Kowannen mu jima ko daga baya fuskanci phrases kamar aspartate aminotransferase karu. Menene wannan yake nufi, ya san ba kowa da kowa. A wannan batun, mun bayyana da labule. A wani m kwayoyin da enzyme dauke a cikin sel ce kayan ciki, shi ne na kullum. Kawai karamin sashi na AST iya shiga cikin jini. Bayani - da taro na enzyme a cikin zuciya fiye da adadin jini ya kwarara zuwa 10 sau dubu.

Amma idan nama na wani sashin jiki ta lalace, da aspartate aminotransferase, sakewa, a cikin jini da kuma adadin na enzyme fara ƙara. The girma kudi ya dogara da mataki na nama lalacewa. Alal misali, a cikin ganewar asali na tsokar zuciya infarction, AST taro ya kai wani ganiya bayan rana.

A wasu lokuta, da enzyme matakin na iya wuce cikin kudi na 5 sau, da kuma irin nuna alama za a iya kiyaye for 7 kwanaki. Kuma a sa'an nan wani zai yi mamaki idan aspartate aminotransferase (AST) ya karu, abin da ake nufi? Wannan babban aiki ne a hallmark na tsanani yanayin haƙuri, wanda sau da yawa ƙare unfavorable sakamako.

Idan da karuwa a enzyme yawa faruwa hankali da kuma kara kudi ba, yana nufin cewa infarct zone qara. aspartate aminotransferase aiki zai iya tsokana a mutuwa kashe na hanta nama.

Abin da zai iya barazana ga babban aiki na AST?

Sau da yawa, wani babban taro na AST a cikin jini rafi sa shi tsokar zuciya infarction. Lokacin da wannan adadin enzyme iya zama fiye da 10 sau da kullum, da kuma mafi girma shi ne, da girma fannin cardiac tsoka raunuka. A rana ta huɗu na magani mafi yawa ana ba reanalysis. Ya sakamakon nuna, aspartate aminotransferase ya karu ko ba. A hali na tasiri far kamata rage ta maida hankali.

Babban matakin AST za a iya lura a raunuka na hanta saboda da dalilai da dama:

• Oncological cututtuka.
• Barasa guba.
• Kiba.
• A gaban HCV.

Kawai a cikin wannan harka, don yin wani cikakken ganewar asali, shi wajibi ne su gudanar da ƙarin gwaje-gwaje. Duk da haka, dagagge matakan da enzyme iya zama a in ba haka ba lafiya mutane. Alal misali, aiki na iya zama:

• The yara a gaban kumburi.
• A mata a lokacin farko da trimester ciki.
• Idan wuce kima yin amfani da giya.
• Lokacin da shan wasu magungunan: valerian, daban-daban maganin rigakafi ko paracetamol.

Great motsa jiki, kuma, da a cikin wannan girmamawa da wani mummunan tasiri. Bugu da kari, idan aspartate ne ƙãra, da dalilai iya lurking a cikin yin amfani da shirye-shirye dangane da barbituric acid ci na hana kuma iya kai wa ga wani karuwa a AST.

Dalilan da kara AST

Sanadin kara matakan da enzyme, kamar yadda riga aka ambata a sama, ƙila a sami wata tsokar zuciya infarction. Tare da wannan ganewar asali a 95-98% na dukan marasa lafiya rajista high aiki na aspartate aminotransferase. The darajar iya zama har zuwa 3,000 raka'a nuna alama. / L. A wasu lokuta, high matakan da enzyme lura a hanta necrosis. Cutar da ake, bi da bi, za a iya lalacewa ta hanyar daban-daban siffofin hepatitis. A matakin na AST a cikin wannan hali ya wuce na al'ada dabi'u 10-100 sau.

Daga cikin sauran cututtuka kamata a lura da angina, m pancreatitis, toshewa da bile ducts, ciwon daji Kwayoyin ko hanta metastases. Wani enzyme taro iya ƙara saboda rauni, da kuna aiwatar fara mutuwa tsoka Kwayoyin fallasa su zafi tura. Wannan na iya kuma sun hada da haƙuri a cikin postoperative zamani.

Abin da aspartate aminotransferase karu da yaro, shi iya nuna gaban hepatitis, murdede dystrophy, m myocarditis, jaundice.

A dalilan ragewan AST

enzyme matakan iya ba kawai ƙara amma kuma raguwa. Wannan ya faru domin daban-daban dalilai. Matsayin mai mulkin, da shi ya auku a ciki mata. A wasu lokuta a yara da kuma manya saboda murdede dystrophy, raunin da ya faru, yana mai sãɓãnin mai tsanani, cerebral infarction, hypothyroidism ko m pancreatitis kiyaye rage matakin aspartataminotraferazy. Saboda rashin bitamin B6, ko da katsewa na hanta ne ma kamu rashi na sunadari.

Alamomi ga analysis nufi

A analysis domin sanin matakin da enzyme AST kamata a da za'ayi domin gane gaban wasu tsanani pathologies:

• faruwa idan ciwon daji matakai a cikin hanta Kwayoyin.
• ko akwai metastases.
• aspartate aminotransferase ya karu jini iya nuna gaban dauke da kwayar cutar mononucleosis ko kwayar cutar na lymphatic tsarin.
• irin autoimmune cuta (msl, DMD-Becker) .
• tsokar zuciya infarction.
• cirrhosis.
• analysis kuma nuna gaban wani siffofin hepatitis, ciki har da hanta necrosis.

Bugu da kari, da abnormality na tsokoki da kuma hanta, kamar yadda wani m, da su sa mutane tunani game da isar da bincike.

Kawai sakamakon iya tabbatar da ko shanyewa da ganewar asali. Wannan zai ba da damar ya dauki matakan da suka dace a lokacin. Idan wani manyan canje-canje da suka faru, shi ne kawai ga mafi alhẽri.

Shiri - wani muhimmin yanayin

Kamar yadda nassi na wasu Nazarin auku bincike dole ne a bi da tsanani kamar yadda shan magunguna, ko yana da wani likita ta nada magani ko na ganye decoction, iya adversely shafi sakamakon bincike ya zama m.

Saboda haka, to san daidai, aspartate aminotransferase ya karu ko ba, kana bukatar ka daina shan magani. Idan kuma wani dalilin wannan ba zai yiwu, ya kamata a sanar da likita wanda ya bukatar ya samar da dukkan bayanai game da miyagun ƙwayoyi. Wato, da sashi da kuma lokacin da tallafi. Mata awon gwaji iya halakarwa a ciki.

Analysis da aikata nagartacce

Abu domin gudanar da bincike na musamman ne venous jini ko magani. Its daukan samfur da aka yi a kan komai a ciki da safe. A dukan hanya ba ya dauki lokaci mai tsawo da kuma daukan wuri ba tare da jin zafi. A sakamakon haka ne shirya bayan 6-10 hours. A magani za a iya adana for 48 hours at zazzabi na 15-25 digiri. A sanyaya yanayi (2-8 ° C) gabancin game 6 days.

Amma ga tambaya, inda shi ne mai yiwuwa a wuce da irin wannan bincike, shi wajibi ne su yi amfani da musamman dakunan gwaje-gwaje da cewa yin biochemical da ƙididdiga. A wasu lokuta, don koyi AST (aspartate aminotransferase) ta ƙara ko al'ada, za ka iya zuwa binciken a asibitin a gidansa, ko kuma wani likita jihar ma'aikata. Kawai dole ne ka farko gano ko ta Lab da zama dole kayan aiki da kuma kayayyakin aiki, domin bincike.

Al'ada matakai a kowane rukuni na mutane suna da nasu. Alal misali, taro na AST a cikin jariri ne 25-75 U / L, yayin da dan kadan mazan yara (1-18 shekaru), shi ne 15-60 U / L. Al'ada matakai a mata Range daga 10 zuwa 36-U / l, kuma a cikin maza - daga 14 zuwa 20 U / L.