Bile acid sequestrants, kwayoyi: jerin

m acid sequestrant kwayoyi suna kira, suna iya rage jini cholesterol. Wannan karin miyagun ƙwayoyi amfani da magani. Akwai tabbataccen rarrabuwa na sia-ragewan kwayoyi, wanda hana cholesterol hada a cikin jini. Sequestering jamiái suna kunshe a cikin wannan rarrabuwa. Shi ne matukar, ya ƙunshi wani iri-iri na kayan aikin, wanda ya yi kama da inji na mataki. Mafi sani bile acid sequestrants - kwayoyi "Colestipol", "Cholestyramine", "colesevelam."

Hadarin na cututtukan zuciya da an rage ta sequestering Properties, ciki har da ischemia. Clinical kwarewa tabbatar da tasiri na SCF a cikin wadannan abubuwa:

• rikitarwa da jijiyoyin zuciya hali ne inda hakan.
• rage mutuwar daga tsokar zuciya infarction.

A sunadarai abun da ke ciki na wadannan kwayoyi damar da su ka hada da fannonin da na ion musayar resins. Wannan high kwayoyin nauyi roba mahadi wanda suke da gaske insoluble polymers ne m shiga tare da mai ruwa-ruwa matsakaici a cikin ion musayar tsari. Wannan abin da sequestering bile acid.

Ginshikai na mataki na kwayoyi

The kalmar "sequestrant" na nufin "insulator", cewa ke faruwa a jikin mutum kadaici da bile acid. Cholesterol ta ɗaure da bile acid, wanda kawo cholesterol daga hanta da kwarara domin sakamako da kira. Bile acid circulating a cikin narkewa kamar tsarin kafin su isa hanji, inda aka ba tunawa. A sakamakon haka, jiki ne mai yawa m abubuwa ga rayuwa.

Tasiri da sakamakon ne lipoproteins da cewa suna da wani low yawa. Wannan ake kira bad cholesterol.

Tun da aikin bile acid sequestrants (shirye-shirye bayyana a cikin mafi daki-daki a kasa).

Sequestrants ba tunawa a cikin jini, don haka illa idan wani, shi ne a mafi ƙarancin matakin, da kuma suka bayyana sosai da wuya.

Ciki da kuma lactating mata da suka za a iya amfani da wadannan dalilai. Har ila yau, yara da kuma matasa da iyalinmu hypercholesterolemia suna shan wadannan kwayoyi zuwa rage gudu da tsari. Yana da wani gaji yanayin jiki, a cikin abin da pronounced high cholesterol da kuma sakamakonsa sakamakon.

Idan portability FFA al'ada, za ka iya amfani da su domin quite lokaci mai tsawo. Noobyazatelno bukatar sarrafa cholesterol, hanta enzymes da tsoka nama.

Statins a hade tare da FFA ne mafi tasiri da tsawo hanya na far. A bad cholesterol an rage da rabi. Idan akwai wani hada hyperlipidemia (a lokacin da wani yawa na fats a cikin jini), sa'an nan sakamakon zai kasance mafi alhẽri daga 70-75%. Kamar yadda jiki yi a kan bile acid sequestrants? A formulations aka kullum da kyau jure.

Mene ne illa?

Side effects faruwa sosai da wuya. Idan sun kasance, sa'an nan kome tsanani ga jiki ba ya juya. Duk da haka, wasu mutane na iya zama wata alama da wadannan cututtuka wuce da sauri:

• maƙarƙashiya.
• bacin (dyspepsia).
• tashin zuciya.
• wuce kima gas samuwar a cikin hanji (flatulence).
• bloating.
• ƙwannafi, kuma shi ne ya fi kowa gefen sakamako na bile acid sequestrants.

Domin kauce wa korau halayen a kan sashi na jiki, kana bukatar ka sha yalwa da ruwaye da kuma ci a farkon magani a kananan allurai.

Lokacin amfani da FFA yara bukatar su zuwa rubũta baƙin ƙarfe da kuma folic acid. Lokaci daya da magani tare da wasu kwayoyi na iya haifar da matalauta sha na aiki aka gyara. Ga shi wajibi ne don tsayar da wadannan mulki: sequestering sha awa bayan amfani da wasu wajen, kuma domin hudu kafin.

Sosai da wuya yiwu tsoka zafi (myalgia), kumburi da pharynx (makogwaro). Musamman wuya faru na tari, zafi a baya, sanyi.

contraindications

Kada contraindications sequestering bile acid? Kwayoyi da aka ba wajabta a cikin wadannan lokuta.

Lokacin da hyperlipidemia irin 3 da 4 (wanda barazana pathologies na zuciya da jijiyoyin jini tsarin) ba su shawarar sequestrants. Iya ta da triglycerides a cikin jini. Lokacin da buga da bile bututu (biliary cirrhosis da cikakken biliary toshewa) ba zai iya sanya data medicaments. Idan wani mutum ne yake shan wahala daga m maƙarƙashiya, da miyagun ƙwayoyi iya kawai tsananta halin da ake ciki. Koda cuta, ciki ulcers, basur, zub da jini cuta - duk contraindications zuwa SLC.

Tare da kula rubũta su ga mutane da gastrointestinal cuta, malabsorption ciwo (sosai hanji sha, da kuma muhimmanci na gina jiki da wuya a zauna a jiki).

Zai yiwu kawai idiosyncrasy.

Wadannan look at mafi mashahuri bile acid sequestrants. Kwayoyi (jerin iya kuma duba tare da likita) za a shirya domin daga mafi mashahuri to kalla rare.

Da miyagun ƙwayoyi "Cholestyramine"

Haka kuma an kira "Cholestyramine". Fili ne insoluble ion musayar resins. Yana take kaiwa zuwa wani raguwa a jini cholesterol matakan da kwata. Shin wani aiki nauyin bile acid, sa'ilin da suka suna ware daga jikin mutum. Idan da miyagun ƙwayoyi ne dole sha na dogon lokaci, to, kana bukatar ka yi amfani da karin ruwa. Statins bunkasa effects, amma su maida hankali ne rage a cikin jini. A cikin shekaru 60 da shekaru wajabta tare da taka tsantsan.

Medicament "Colestipol"

Yana da wani babban insoluble copolymer. Kadarorin daura bile acid ne dan kadan ya fi muni a shi fiye da "Kolestiramin".

Alamomi, illa kuma contraindications ne guda kamar yadda dukan rukuni na kwayoyi. A hade da "Kolestepola" da kuma statins bayar da mafi kyau sakamako.

Drug "colesevelam"

Babu m dandano Properties daga cikin samfurin taimaka wa da cewa shi aka ƙara ana amfani da a kwatanta da sauran magunguna.

Shin da data sequestering bile acid da illa?

Illar kan gastrointestinal fili aka lura. Halayen da wasu magunguna ba. "Colesevelam" za a iya amfani da magani daga ciki da kuma lactating mata.